Clinical trials: TMD/Orofacial Pain, open to volunteers
Chronic Orofacial Pain, Temporomandibular Disorder (TMD)
Orofacial Pain Self-management: Personality Moderation Effect
The objective of this clinical trial is to study the effect of self-management on pain perception in patients with chronic orofacial pain and temporomandibular disorders (TMD) comparing it with the conventional treatment proposed…
- Conditions
- Chronic Orofacial Pain, Temporomandibular Disorder (TMD), Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD)
- Trial name
- NCT06932406
- Testing
- Self-management intervention, Clinical Practice Guideline Intervention
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Temporomandibular Disorders (TMD), Orofacial Pain
Comparing the Effectiveness of Online vs. Face-to-face Physiotherapy for Treating Temporomandibular Disorders
Dentists and physiotherapists have two options for treating these conditions: splint therapy and physiotherapy. Right now, the gold standard is individual physiotherapy, which contains manual therapy and active exercises too.
- Conditions
- Temporomandibular Disorders (TMD), Orofacial Pain, Temporo-mandibular Dysfunction, Temporomandibular Joint and Muscle Disorder
- Trial name
- NCT07474662
- Testing
- Individual physiotherapy, Group physiotherapy, Online physiotherapy
- Where
- 2 sites in Hungary
- Volunteers
- 90 people
- Sponsor
- Semmelweis University
Myogenic Temporomandibular Joint Disorders, Myofacial Pain
Efficacy of PRP Injections in Reducing Pain for Myogenous TMD Patients
This study aims to evaluate whether intramuscular injections of platelet-rich plasma (PRP) are more effective than isotonic saline in reducing pain and improving jaw function in individuals diagnosed with myogenous…
- Conditions
- Myogenic Temporomandibular Joint Disorders, Myofacial Pain, Masseter Muscle
- Trial name
- NCT07606378
- Testing
- Saline (0.9% NaCl), Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
TMD, TMD/Orofacial Pain
Effects Exercises in Temporomandibular Joint Disorders on Pain, Joint and Tongue Functions
The goal of this clinical trial is to learn if orofacial exercises works to treat temporomandibular disorders in adults. It will also learn about the safety of orofacial exercises on temporomandibular disorders.
- Trial name
- NCT07304557
- Testing
- Exercise, Manual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Tayfun ISIK
Temporomandibular Disorders (TMD)
Aerobic Physical Activity and Orofacial Myofascial Pain
Orofacial myofascial pain, most commonly represented by Temporomandibular Disorders (TMD) a significant public health, affecting approximately 12% to 14% of the general population.
- Trial name
- AERODOF (NCT07526688)
- Testing
- Temporal Summation of Pain and Questionnaire
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Bruxism, Pelvic Floor Disorder
Bruxism and Pelvic Floor Dysfunction in Young Women
Bruxism and Pelvic Floor Dysfunction in Young Women
- Conditions
- Bruxism, Pelvic Floor Disorder, Young Adult Females, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07437924
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
TMJ Disc Disorder, Temporomandibular Joint Disc Displacement, Without Reduction
Arthroscopic Lysis and Lavage With and Without Intra-articular Injection of Hyaluronic Acid in Patients With DDwoR in TMJ
The study aims to assess the outcomes of arthroscopic lysis and lavage procedure with and without single intra-articular injection of hyaluronic acid in managing patients with anterior disc displacement without reduction.
- Conditions
- TMJ Disc Disorder, Temporomandibular Joint Disc Displacement, Without Reduction, TMD/Orofacial Pain, Temporomandibular Disorder
- Trial name
- NCT07614932
- Testing
- Arthroscopic lysis and lavage, arthroscopic lysis and lavage with intra-articular injection of hyaluronic acid
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Temporomandibular Disorders (TMDs), Temporo-mandibular Dysfunction
Effects of Orofascial Myofunctional Therapy and Cervical Stabilization Exercises on Temporomandibular Dysfunction
Temporomandibular disorders (TMDs) are among the most common musculoskeletal conditions affecting the craniofacial region and are characterized by pain, joint sounds, restricted movement, and functional limitations.
- Conditions
- Temporomandibular Disorders (TMDs), Temporo-mandibular Dysfunction, Disc Displacement
- Trial name
- OMT (NCT07828587)
- Testing
- orofacial myofunctional therapy, cervical stabilization exercises
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Lahore University of Biological and Applied Sciences
TMD/Orofacial Pain, Myalgia of Mastication Muscle
Botulinum Toxin in the Management of Temporo-mandibular Related Myalgia: a Prospective Study
The aim of this study was to evaluate the clinical course in terms of pain, function and quality of life of patients with TMD-related myalgia during six months after receiving BTX-A injections.
- Conditions
- TMD/Orofacial Pain, Myalgia of Mastication Muscle, Botulinum Toxin, Type a
- Trial name
- BOMAMY (NCT06677216)
- Testing
- Botulinum Toxin, Type A
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Diakonessenhuis, Utrecht
Temporomandibular Joint Dysfunction; Myofascial Pain Syndrome; Orofacial Pain; Musculoskeletal Disorders
Reflex Therapy of Temporomandibular Dysfunctions
This study aims to evaluate the effectiveness of dry needling in patients with functional temporomandibular pain syndrome by comparing standard rehabilitation therapy alone with therapy combined with dry needling to reduce pain…
- Trial name
- NCT07321483
- Testing
- Dry needling, Standard rehabilitation
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Palacky University
Chronic Masticatory Myofascial Pain
Masticatory Muscle Activity Using a 24-Hour Wearable Device
Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to…
- Trial name
- NCT07861906
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Temporomandibular Disorders (TMD)
Prevalence of Temporomandibular Joint Disorders in Wind Musicians
This study aims to analyze the prevalence of temporomandibular joint disorders (TMD) in wind musicians, differentiating the impact by instrument type (woodwind vs.
- Trial name
- TMD-WIND (NCT06823531)
- Testing
- Not applicable (Observational Study)
- Volunteers
- 50 people
- Sponsor
- University of Oviedo
Temporomandibular Disorder
K23- Physical Self Regulation vs Placebo
This study will use a between-person design. Participants will be treatment-seeking patients with chronic masticatory muscle pain.
- Trial name
- NCT06357702
- Testing
- Physical Self Regulation Telehealth, Psycho-education Telehealth
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Ian Boggero, PhD
Temporomandibular Disorder (TMD)
Marine Lipids Ease Painful TMD
The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic…
- Trial name
- ADAPT (NCT07437313)
- Testing
- SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
TMD/Orofacial Pain, Malocclusions
Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device
Condylar position and mandibular motion assessment with digital facebows Arcus Digma III before and after orthognathic surgery.
- Trial name
- NCT07828041
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle
Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST)
Chronic temporomandibular disorders (TMDs) affect the masticatory muscles, the temporomandibular joints (TMJs), and associated structures. Except in cases of trauma, their etiology remains uncertain, debated, and multifactorial.
- Conditions
- Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle, Arthralgia Syndrome
- Trial name
- OEST (NCT07445516)
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Urbano Santana Penin
Temporomandibular Joint Disorder, Temporomandibular Disorders (TMDs)
ePROPP - eHealth for Preventing and Reducing Orofacial Pain in the Population
Pain in the orofacial region has a 10% prevalence in the general population and health care providers are therefore expected to encounter these patients on a daily basis.
- Trial name
- ePROPP (NCT07095101)
- Testing
- Mobistudy Application, Occlusal splint
- Volunteers
- 120 people
- Sponsor
- Malmö University
Mastication Disorder, Fatigue
Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).
Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain…
- Conditions
- Mastication Disorder, Fatigue, Temporomandibular Disorder, Orofacial Pain
- Trial name
- F-6MMT (NCT06298786)
- Testing
- Functional 6-minute mastication test
- Where
- 3 sites in Spain
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Temporomandibular Disorders (TMDs), Kinesiophobia
The Italian Version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD)
This observational, cross-sectional study aims to translate, culturally adapt, and psychometrically validate the Italian version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD-ITA).
- Trial name
- TSK-TMD-ITA (NCT07750509)
- Volunteers
- 250 people
- Sponsor
- Alessandro Aquino
Temporomandibular Disorder, Orofacial Pain
An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular Disorders
Temporomandibular disorders (TMD) encompass a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures.
- Trial name
- NCT07639944
- Testing
- Nerivio treatment
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Theranica