Clinical trials: TMJ, open to volunteers
Confidence, Diagnostic Ability
Testing Educational Modalities for Temporomandibular Disorders Curriculum
This study is done to assess the change in confidence level, knowledge, and diagnostic ability in TMD-related aspects through the exposure to a Virtual Patient-Based Learning (VPBL) platform featuring temporomandibular disorder…
- Trial name
- NCT07203456
- Testing
- Virtual Patient Based Learning (VPBL), Clinical exposure to patients with TMD, Clinical exposure to TMD + VPBL
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Temporomandibular Joint Osteoarthritis
Intra-articular Allocetra in Osteoarthritis of the of the Temporomandibular Joint (TMJ)
This study is a single center trial to assess the safety and initial efficacy of intra-articular administration of Allocetra to patients with Temporomandibular Joint Osteoarthritis (TMJ-OA)
- Trial name
- NCT06748651
- Testing
- Allocetra
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- Dr. Amit Druyan
Posture
Postural Perturbations Tracing to the Stomatognathic System
A connection of the stomatognathic system [an anatomical system comprising the teeth, jaws, and associated soft tissues] to postural control has been suggested in the literature.
- Trial name
- NCT06974591
- Testing
- Dental splints, Dentures
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston University
TMJ Disc Displacement With Reduction, TMD
ARS vs ARS With Arthrocentesis and PRP Injection in DDWR
This study will be conducted to assess the effect of anterior repositioning splint and arthrocentesis with platelet-rich plasma injection compared to anterior repositioning splint only, in TMD patients with anterior disc…
- Conditions
- TMJ Disc Displacement With Reduction, TMD, PRP Injection
- Trial name
- NCT07115797
- Testing
- arthrocentesis - PRP injection -ARS, ARS
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Myogenic Temporomandibular Joint Disorders, Myofacial Pain
Efficacy of PRP Injections in Reducing Pain for Myogenous TMD Patients
This study aims to evaluate whether intramuscular injections of platelet-rich plasma (PRP) are more effective than isotonic saline in reducing pain and improving jaw function in individuals diagnosed with myogenous…
- Conditions
- Myogenic Temporomandibular Joint Disorders, Myofacial Pain, Masseter Muscle
- Trial name
- NCT07606378
- Testing
- Saline (0.9% NaCl), Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Temporomandibular Disorder
Electrical Stimulation of the Mandibular Nerve for Pain and Function Management in Temporomandibular Disorders
Temporomandibular disorders (TMD) encompass dysfunction and pain of the masticatory muscles and temporomandibular joint (TMJ). Pain in the TMJ, restricted jaw movement, and joint sounds are common conditions in this disorder.
- Trial name
- Origenkine (NCT06265636)
- Testing
- Percutaneous nerve stimulation, Manual therapy, exercise
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- OrigenKinesis fisioterapia
Temporomandibular Disorders (TMD)
Effects of a Biopsychosocial Approach Added to Physiotherapy in Temporomandibular Disorders
Temporomandibular disorders are conditions that affect the jaw joint and surrounding muscles and may cause pain, limited jaw movement, stress, sleep problems, and teeth grinding.
- Trial name
- TMD-BPS (NCT07320144)
- Testing
- Physiotherapy Program, Biopsychosocial Intervention
- Volunteers
- 40 people
- Sponsor
- Betül Özata
Temporomandibular Joint Disorders
Long-term Safety and Performance of Materialise's Patient-specific TMJ System.
This is a long-term (10 years), retrospective-prospective, observational, single-arm, monocenter study of patients to be treated with the Materialise TMJ Total Arthroplasty System for TMJ replacement.
- Trial name
- NCT06951178
- Testing
- TMJ Total Arthroplasty System (TMJ System)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Materialise
TMJ - Oral &Maxillofacial Surgery, Oral and Maxillofacial Conditions
Biologic Augmentation of TMJ Arthroscopy Using BMAC
The goal of this clinical trial is to learn about the efficacy of using Bone Marrow Aspirate Concentrate (BMAC) during temporomandibular joint (TMJ) arthroscopy compared to standard arthroscopic procedures with corticosteroid…
- Conditions
- TMJ - Oral &Maxillofacial Surgery, Oral and Maxillofacial Conditions, TMJ Pain, TMJ Arthralgia
- Trial name
- NCT07536399
- Testing
- Bone Marrow Aspirate Concentrate, Corticosteroid (CS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
TMD, TMD/Orofacial Pain
Effects Exercises in Temporomandibular Joint Disorders on Pain, Joint and Tongue Functions
The goal of this clinical trial is to learn if orofacial exercises works to treat temporomandibular disorders in adults. It will also learn about the safety of orofacial exercises on temporomandibular disorders.
- Trial name
- NCT07304557
- Testing
- Exercise, Manual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Tayfun ISIK
TMJ Disc Displacement With Reduction
Therapeutic Effect of Using Injectable Hypertonic Saline 5% Versus Injectable Dextrose 20% on Pain in Painful Cases of Disc Displacement With Reduction
This study is aiming to assess effect of hypertonic saline 5% in comparison to dextrose 20% on pain ,inter-insical opening and movements of jaw in painful cases of disc displacement with reduction
- Trial name
- RCT (NCT06839430)
- Testing
- hypertonic saline 5% sodium chloride, hypertonic dextrose 20%
- Volunteers
- 20 people
- Sponsor
- Cairo University
Temporomandibular Disorders (TMD)
Aerobic Physical Activity and Orofacial Myofascial Pain
Orofacial myofascial pain, most commonly represented by Temporomandibular Disorders (TMD) a significant public health, affecting approximately 12% to 14% of the general population.
- Trial name
- AERODOF (NCT07526688)
- Testing
- Temporal Summation of Pain and Questionnaire
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Temporomandibular Joint Disorders, Myofascial Pain Syndromes
Post-Isometric Relaxation in Temporomandibular Disorders
This planned randomized, single-blind clinical trial will investigate the effects of adding the Post-Isometric Relaxation (PIR) technique to a standard postural exercise program in individuals with moderate to severe…
- Conditions
- Temporomandibular Joint Disorders, Myofascial Pain Syndromes, Mandibular Dysfunction
- Trial name
- PIR-TMD (NCT07130279)
- Testing
- Postural Exercises + Post-Isometric Relaxation (PIR) Technique, Postural Exercises
- Volunteers
- 40 people
- Sponsor
- Sanem ŞENER
Myofacial Pain, Myofacial Pain Syndrome
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome
This study is designed to evaluate a method to improve the treatment of myofascial pain syndrome (MPS), a common condition that causes muscle pain, tenderness, and reduced movement due to the presence of trigger points in…
- Conditions
- Myofacial Pain, Myofacial Pain Syndrome, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
- Trial name
- BIC-LIDO-MPS (NCT07572994)
- Testing
- Lidocaine 2 %, Lidocaine + Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Chronic TMD Pain, Temporomandibular Disorder
R01_Pilot Jaw Muscle Phenotypes
The proposed study will assess the effect of local heat therapy on jaw pain and jaw fatigue secondary to a teeth clenching task in chronic TMD pain cases.
- Trial name
- NCT07153107
- Testing
- Local Heat Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Temporomandibular Joint Disorders
Pain Science Education Administered in Full or Fractioned Dosage Modes for Temporomandibular Disorders
Temporomandibular Disorders (TMD) are a collection of musculoskeletal disorders which affect the masticatory structures and have a multifactorial etiology.
- Trial name
- NCT06259344
- Testing
- Fractioned Pain Science Education (FPSE), Full Dosage Mode Pain Science Education (FDPSE), Manual Therapy
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Federal de Sao Carlos
Temporomandibular Disorders
Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A
The goal of this clinical trial is to investigate the effect of botulinum toxin on neurons' plasticity in the masseter muscle in humans with and without painful myogenous temporomandibular disorders (TMDM).
- Trial name
- NCT05720065
- Testing
- Botulinum toxin type A, Isotonic saline 0,9%
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Temporomandibular Disorder, Temporomandibular Joint Disorders
Cognitive Exercise Therapy Approach Biopsychosocial Questionnaire (BETY-BQ) in Patient with Temporomandibular Disorders
The aim of this study is to investigate the validity, reliability, and responsiveness of the Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (BETY-BQ) in individuals with temporomandibular disorder.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
- Trial name
- NCT06186830
- Testing
- Validity and reliability analyses
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hacettepe University
Bruxism, Pelvic Floor Disorder
Bruxism and Pelvic Floor Dysfunction in Young Women
Bruxism and Pelvic Floor Dysfunction in Young Women
- Conditions
- Bruxism, Pelvic Floor Disorder, Young Adult Females, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07437924
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University