Clinical trials: Tailored Condition
Prostate Cancer
Using a mHealth App to Improve Quality-of-Life Outcomes in Black Prostate Cancer Survivors
The goal of this clinical trial is to ensure that the mobile health application for Black patients with prostate cancer (either actively undergoing treatment or survivors) is usable and acceptable to patients, get feedback about…
- Trial name
- NCT06651359
- Testing
- Surveys for Quality of Life, Surveys and mHealth App access
- Where
- 3 sites in United States
- Volunteers
- 248 people
- Sponsor
- University of Oklahoma
Amyotrophic Lateral Sclerosis (ALS)
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS
Amyotrophic Lateral Sclerosis (ALS) is a severe and incurable neurodegenerative disease of motor neurons with a dramatic socio-economic impact on the national health system.
- Trial name
- PERMEALS (NCT06917924)
- Testing
- lumbar puncture
- Where
- 4 sites in Italy
- Volunteers
- 200 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Breast Cancer
Studying Tailored Exercise Prescriptions in Breast Cancer Patients
Chemotherapy forms a significant part of many breast cancer patient's treatment and is associated with various common, known adverse effects.
- Trial name
- STEPS (NCT02802826)
- Testing
- Tailored Exercise Prescription
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Loughborough University
Ovary Cancer, Endometrial Cancer
Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)
The primary purpose of the study is to determine which of four components (symptom-burden tailored app, exercise partner, oncology provider engagement, coaching) added to a core intervention of a wearable activity tracker and…
- Conditions
- Ovary Cancer, Endometrial Cancer, Uterine Cancer, Cervical Cancer
- Trial name
- NCT05743517
- Testing
- Fit4Treatment
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Northwestern University
Breast Cancer, Sentinel Lymph Node
Omission of Axillary Surgery in Breast Cancer Patients
The treatment and prognosis of breast cancer (BC) are dependent on its molecular subtype and nodal burden. In early BCs with favourable molecular subtype, the incidence of axillary node involvement is low.
- Conditions
- Breast Cancer, Sentinel Lymph Node, Breast Neoplasms
- Trial name
- NCT06259513
- Testing
- omission of SLNB in SentiOMIT or omission of ALND in SentiMACRO
- Where
- Singapore
- Volunteers
- 350 people
- Sponsor
- KK Women's and Children's Hospital
Hepatitis C, HIV Coinfection
Supporting Treatment Outcomes Among PWID
The goal of this study is to improve HCV care continuum outcomes for people who inject drugs (PWID), reduce potential onward transmission to others and improve HIV outcomes among those who are HIV/HCV coinfected.
- Trial name
- STOP-C (NCT04652804)
- Testing
- Low intensity HCV treatment adherence support, Medium intensity HCV treatment adherence support, High intensity HCV treatment adherence support
- Where
- India
- Volunteers
- 3,000 people
- Sponsor
- Johns Hopkins University
Venous Thromboembolism, Venous Thromboses
Leiden Thrombosis Recurrence Risk Prevention
The goal of this clinical trial is to evaluate tailored duration of long-term anticoagulant treatment after a first venous thromboembolism based on individualized risk assessments of recurrent VTE and major bleeding risks.
- Conditions
- Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- L-TRRiP (NCT06087952)
- Testing
- Randomised treatment advice (discontinue vs continue after 3 months), VTE-BLEED score, L-TRRiP score
- Where
- 19 sites in Netherlands
- Volunteers
- 608 people
- Sponsor
- Leiden University Medical Center
Hypertension
Individually Tailored Web-Based Program to Improve Blood Pressure Control
High blood pressure affects 65 million adults in the United States, and more than one third of these individuals do not have adequate control of their blood pressure.
- Trial name
- NCT00377208
- Testing
- Web-Based Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Neuropathic
Pulsed Electromagnetic Field Therapy to a Tailored Exercise Program for Patients Suffering From Chemotherapy-induced Neuropathy Related to Breast Cancer
This research studied the usefulness of a targeted intervention designed to manage chemotherapy-induced symptoms, particularly focusing on pain relief, balance deviations and functional improvements.
- Trial name
- PEMFTEPCHIN (NCT06947577)
- Testing
- pulsed electromagnetic field (PEMF) therapy and a tailored exercise program (TEP), Tailored Exercise Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Atrial Fibrillation
Safety Study on Stopping Anticoagulation Medication in Patients With a History of Atrial Fibrillation
The purpose of this study is to determine whether it is safe to stop anticoagulation medication in patients with a history of atrial fibrillation (AF) based on information from a pacemaker or implantable cardioverter…
- Trial name
- TACTIC AF (NCT01650298)
- Testing
- Drug (Direct thrombin or Factor Xa inhibitor)
- Where
- 10 sites in United States
- Volunteers
- 64 people
- Sponsor
- Abbott Medical Devices
Aortic Aneurysm, Abdominal
Adherence and Acceptability of a Remote, Home-based, Pre-surgery Programme for Patients Undergoing Abdominal Aortic Aneurysm Surgery
Design A multi-centre pilot study investigating the acceptability and adherence of a prehabilitation on patients requiring abdominal aortic aneurysm repair. Setting 3 NHS Hospital Vascular Surgery Clinics in the UK.
- Trial name
- NCT04792411
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Cirrhosis, Ascites
The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.
This study is being completed for patients with cirrhosis, including patients with a prior history of hepatic encephalopathy (HE) to evaluate the feasibility and benefits of medically-tailored meals as an intervention.
- Conditions
- Cirrhosis, Ascites, Liver Diseases, Frailty
- Trial name
- NCT04675775
- Testing
- Medically-tailored meals (MTM), Protein supplements, Nutrition education handout
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Michigan
Type 2 Diabetes
Culturally Appropriate Strategies for Chinese Americans With Diabetes (CASCADe)
The project aimed to evaluate the implementation process and efficacy of a culturally tailored Diabetes Self-Management and Education (DSME) program with mobile health (mHealth) technology integration, entitled Culturally…
- Trial name
- NCT04737499
- Testing
- CASCADe
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Claremont Graduate University
Physical Therapy, Resistance Exercise
Resistance Exercise and Sleep Quality by Chronotype
This study examines whether doing moderate resistance exercises in the morning can improve sleep quality and well-being in young adults.
- Conditions
- Physical Therapy, Resistance Exercise, Sleep Disturbances, Sleep Quality
- Trial name
- TRE-SLEEP (NCT07234812)
- Testing
- Moderate-Intensity Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medipol University
Skin Cancer
Skin Cancer Prevention in a Pediatric Population
Skin cancer risk is largely determined by sun exposure during childhood. This study determines the effectiveness of a mailed intervention designed to increase sun protection for children age 6-9 years old.
- Trial name
- NCT01464957
- Testing
- Semi-tailored newsletter
- Where
- United States
- Volunteers
- 867 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Overweight
Project THRIVE: Evaluating Different Approaches to Dietary Self-Monitoring for Weight Loss
This randomized pilot trial will compare two approaches to dietary self-monitoring for weight loss in the context of a low-intensity, remotely-delivered lifestyle modification program.
- Trial name
- NCT05241353
- Testing
- Reduced Frequency Self-Monitoring, Full-Frequency Self-Monitoring, Standard Behavioral Treatment
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Drexel University
Healthcare Disparities, Minority Health
Tailored Approach to Sleep Health Education: A Community Engaged Approach
This study aims to develop educational tools and platforms to promote the transfer of sleep health information to blacks to foster adoption of healthful sleep practices.
- Conditions
- Healthcare Disparities, Minority Health, Sleep, Sleep Disorders
- Trial name
- TASHE (NCT02507089)
- Testing
- Tailored sleep health education materials., Generic sleep health education materials.
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
ICU Patients, Nutrition Intake
The Effect of a 6-month Dietitian-tailored Nutrition Intervention to Patients With Critical Illness (DETAIL)
This research project aims to study the effect of optimal and individualised nutrition to patients with critical illness during the intensive care unit (ICU) and hospital admission, and until six months after admission.
- Conditions
- ICU Patients, Nutrition Intake, Critical Illness
- Trial name
- DETAIL (NCT07149246)
- Testing
- Nutrition intervention
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- University Hospital of North Norway
Diabetes Mellitus, Type 2
Effectiveness of a Diabetes Education Program Based on Tailored Interventions (Edep-Ti Study)
GOALS: PRIMARY: 1. Analyze the overall impact of the proposed diabetes education program on metabolic control (HbA1c) and modifiable cardiovascular risk factors (lipid profile and blood pressure). SECONDARY: 2.
- Trial name
- Edep-Ti (NCT03453970)
- Testing
- Therapeutic Education Program
- Where
- Spain
- Volunteers
- 410 people
- Sponsor
- University of Malaga
Rheumatoid Arthritis, Spondyloarthritis
The Norwegian Drug Monitoring Study
Infliximab and other TNF-inhibitors have revolutionised the treatment of several immunological inflammatory diseases. Still, more than half of the patients either do not respond sufficiently to infliximab therapy or loose…
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Ankylosing Spondylitis, Crohn Disease
- Trial name
- NOR-DRUM (NCT03074656)
- Testing
- Therapeutic drug monitoring, Standard care
- Where
- 21 sites in Norway
- Volunteers
- 611 people
- Sponsor
- Diakonhjemmet Hospital