Clinical trials: Tailored Condition
Obesity
Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial
The purpose of this study is to develop an evidence-based precision medicine approach for obesity that enhances weight loss and promotes weight loss maintenance.
- Trial name
- NCT06770049
- Testing
- Standard Lifestyle Intervention (SLI) program, Phenotype-tailored Lifestyle Intervention (PLI) program
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Mayo Clinic
Renal Failure
Music Interventions for Patients Undergoing Hemodialysis
Fatigue is found to be one of the most persistent problems among patients in treatment with hemodialysis, and associated with impaired health-related quality of life.
- Trial name
- NCT04959682
- Testing
- Music Intervention
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- University of Southern Denmark
Sleep Disturbances
Individually Tailored Lighting System to Improve Sleep in Older Adults
In conjunction with investigators at the Cecil G. Sheps Center for Health Services Research, University of North Carolina (UNC) at Chapel Hill, we propose to develop and evaluate a low-cost, minimally obtrusive device that…
- Trial name
- NCT01855126
- Testing
- Blue light, Red light
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Rensselaer Polytechnic Institute
Atrial Fibrillation (AF), Atrial Fibrillation Mechanisms
Substrate Remodelling and Targeted Ablation in AF
Atrial fibrillation (AF) is the most common heart rhythm disorder, affecting millions worldwide and causing symptoms such as palpitations, fatigue and breathlessness.
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Mechanisms, Catheter Ablation, Low Voltage Areas
- Trial name
- STRATA-AF (NCT07047235)
- Testing
- Pulmonary vein reisolation, Ganglionic plexi ablation, Substrate ablation
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Barts & The London NHS Trust
Hypertension
Hypertension Intervention Nurse Telemedicine Study (HINTS)
There are 65 million Americans and over 8.5 million veterans who have been diagnosed with hypertension; yet only 31% of all hypertensive patients have their blood pressure (BP) under effective control (less than 140/90 mm/Hg).
- Trial name
- NCT00237692
- Testing
- Nurse Behavioral intervention with Home BP Telemonitoring, Nurse Medication Management with Home BP Telemonitoring, Nurse Combined intervention with Home BP Telemonitoring
- Where
- United States
- Volunteers
- 591 people
- Sponsor
- US Department of Veterans Affairs
Obesity, Metabolic Disease
Conventional Vs Tailored Limb Lengths in Laparoscopic Roux-en Y Gastric Bypass Surgery
The study aims to investigate whether tailoring limb lengths based on the 1/3rd and 2/3rd concept improves clinical outcomes in Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) surgery compared to conventional limb lengths.
- Conditions
- Obesity, Metabolic Disease, Bariatric Surgery Candidate, Metabolic Surgery
- Trial name
- TAILO-R-YGB (NCT06756789)
- Testing
- Laparoscopic Roux-en Y Gastric bypass (RYGB)- Conventional approach, Laparoscopic Roux-en Y Gastric bypass (RYGB)- Tailored approach
- Where
- India
- Volunteers
- 40 people
- Sponsor
- GEM Hospital & Research Center
Osteoarthritis
Using Web-based Tools to Facilitate Tailored Exercise for People With Osteoarthritis
The purpose of this pilot study is to assess the feasibility, acceptability, and potential effectiveness of identifying people with osteoarthritis (OA) who are interested in individualized exercise programs through a web-based…
- Trial name
- exercise/OA (NCT02404974)
- Testing
- exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Insomnia, Insomnia Disorder
Rumination-Tailored Guided Internet-Based CBT-I for University Students
The goal of this clinical trial is to evaluate whether adding rumination-tailored, rule-based personalized feedback to guided internet-based cognitive behavioral therapy for insomnia (iCBT-I) improves treatment outcomes in…
- Trial name
- RUM-CBTI (NCT07623889)
- Testing
- Guided Internet-Based Cognitive Behavioral Therapy for Insomnia (iCBT-I), Rumination-Tailored Rule-Based Personalized Feedback
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Critical Illness
Reducing Post-traumatic Stress Disorder After ICU Discharge With the IPREA3 Program
Reducing discomfort in the intensive care unit (ICU) should be beneficial to longterm outcomes. This study assesses whether a tailored multicomponent program for discomfort reduction may be effective in reducing post-traumatic…
- Trial name
- PTSD-REA (NCT03991611)
- Testing
- Administration of the IPREA3 questionnaire, Immediate feedback through electronic reminder messages, Targeted interventions in each ICU to reduce discomforts
- Where
- 33 sites in France
- Volunteers
- 3,312 people
- Sponsor
- Centre Hospitalier of Chartres
Chronic Pain, Back Pain
CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial
The goal of this clinical trial is to learn whether a combined behavioral and pharmacologic intervention can help reduce opioid use, improve pain recovery, and prevent opioid misuse after surgery in adults undergoing elective…
- Conditions
- Chronic Pain, Back Pain, Neck Pain, Opioid Misuse
- Trial name
- CARES (NCT06027099)
- Testing
- Tizanidine, MI-Opioid Taper, Enhanced Usual Care
- Where
- 4 sites in United States
- Volunteers
- 375 people
- Sponsor
- Stanford University
HIV/AIDS, Smoking Cessation
Learn to Quit-HIV Pilot Study
The study team will conduct a feasibility, acceptability, and preliminary efficacy trial comparing Learn to Quit-HIV (n=30) to an app based on U.S.
- Conditions
- HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
- Trial name
- NCT04609514
- Testing
- Learn to Quit-HIV, QuitGuide, Nicotine patch
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Musculoskeletal Pain
Returning to Work. Efficacy of "Tailored Physical Activity or" "Chronic Pain Self-management Program" in Sicklisted Citizens With Chronic Musculoskeletal Pain
TEst the effect of "Tailored Physical Activity" or "Chronic Pain Self-management Program" on Returning to Work in Sicklisted Citizens With Chronic Pain Related to the Spine or Upper Body
- Trial name
- NCT01356784
- Testing
- Tailored Physical Activity, "Chronic Pain Self-management Programme", Health counselling
- Where
- Denmark
- Volunteers
- 141 people
- Sponsor
- University of Southern Denmark
Type 2 Diabetes Mellitus
Personalizing Self-management in Diabetes - Pilot Study
The goal of this study is to conduct a pilot feasibility study a novel informatics intervention, GlucoType (also called Platano for Latino users) that incorporates computational analysis of self-monitoring data to help…
- Trial name
- NCT04757233
- Testing
- GlucoType
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Heart Failure
Pilot Study Exploring the Feasibility, Acceptability, and Impact of Medically Tailored Meals on Post-Discharge Recovery in Patients With Heart Failure
The goal of this interventional pilot study is to evaluate the feasibility, acceptability, and impact of medically tailored meals (MTM) on post-discharge recovery in patients with heart failure for Penn Medicine patients in…
- Trial name
- HF-MTM (NCT07251894)
- Testing
- Medically Tailored Meals
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Pennsylvania
Breast Cancer
Feasibility of a Modular mHealth for Tailored Rehabilitation of Breast Cancer
This study investigated the feasibility of the novel modular mobile health (mHealth) for personalized rehabilitation and explored the participants' satisfaction and app data during treatment of breast cancer.
- Trial name
- MMHTR (NCT04781712)
- Testing
- Modular mHealth for Tailored Rehabilitation
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Metastatic Breast Cancer
Companion Pharmacogenetic Study to UMCC 9900/9901
The purpose is to examine the original breast tumor material to see how much of a metabolizing enzyme (CYP3A4) is present in tumor material.
- Trial name
- NCT00146029
- Where
- United States
- Sponsor
- University of Michigan Rogel Cancer Center
Diabetes
Healthy Living for You
The goal of the study is to conduct the Healthy Living with Diabetes (HLWD) program among Black individuals in a culturally appropriate manner. This study will involve 24-30 participants in total.
- Trial name
- NCT05917093
- Testing
- Culturally tailored HLWD
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Wisconsin, Madison
Rare Disorders
Channelling Algorithm Proficiency To Understand, Recognise and Elucidate Disease
Rare diseases affect over 3.5 million people in the UK. It can take years of multiple referrals, inconclusive tests or incorrect diagnoses, for patients to get a final diagnosis.
- Trial name
- CAPTURED (NCT07130071)
- Volunteers
- 500 people
- Sponsor
- Research in Real-Life Ltd
Type 2 Diabetes, Diabete Mellitus
E-Health Literacy Intervention for Bangladeshi Migrants With Type 2 Diabetes in Italy
This study is testing a training program for people from the Bangladeshi community of Ancona in the Marche Region (Italy) who have type 2 diabetes.
- Trial name
- JAC_ARS (NCT07783893)
- Testing
- Culturally Adapted eHealth Literacy Training Program
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Marche Region Regional Health Agency
Breast Cancer
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy.
- Trial name
- TAILOR RT (NCT03488693)
- Testing
- Radiation, No Radiation
- Where
- 485 sites in United States, Canada
- Volunteers
- 2,138 people
- Sponsor
- Canadian Cancer Trials Group