Clinical trials: Tailored Condition
Acute Coronary Syndrome
Tailored Antiplatelet Therapy Versus Recommended Dose of Prasugrel
The purpose of this study is to demonstrate the superiority of a strategy of platelet monitoring (Monitoring Arm) with down-adjustment of the dose of prasugrel in high responders and up-adjustment of the dose of prasugrel in low…
- Trial name
- ANTARCTIC (NCT01538446)
- Testing
- Modification of Prasugrel based on a biological assay, prasugrel / clopidogrel, Verify Now
- Where
- 2 sites in France
- Volunteers
- 880 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Disease, Chronic Obstructive
Home Balance Pilot for Fall Reduction in COPD
There is a growing body of evidence demonstrating that older adults with COPD have important problems with their balance and a high incidence of falls compared to those of a similar age.
- Trial name
- NCT02695342
- Testing
- Home balance exercise program
- Where
- 2 sites in Canada
- Volunteers
- 36 people
- Sponsor
- McMaster University
Breast Cancer Prevention, Breast Cancer Risk
A Randomized Controlled Trial to Increase Breast Cancer Screening Uptake
Breast cancer (BC) is the fifth leading cause of cancer deaths in women worldwide. In Hong Kong (HK), BC is the most common cancer, ranking third in cancer deaths among females.
- Trial name
- BCS (NCT06722469)
- Testing
- WCI
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Heart Failure, Left Bundle-Branch Block
Tailor-CRT: Better Application of Cardiac Resynchronization Therapy
Approximately one third of patients treated with cardiac resynchronization therapy (CRT) do not derive any clinical benefit. CRT response can be improved by tailoring LV lead placement and programming of atrio-ventricular (AV)…
- Trial name
- NCT02326493
- Testing
- Cardiac Resynchronization Therapy
- Where
- Netherlands
- Volunteers
- 28 people
- Sponsor
- Maastricht University Medical Center
Heart Failure
CardioInsight 2 - Non-responder
Background Cardiac Resynchronization Therapy (CRT) is proven to improve survival and heart function of patient with certain electrical conduction abnormality and heart failure.
- Trial name
- CardioInsight2 (NCT05555992)
- Testing
- Electrical Activation Mapping Guided Cardiac resynchronization therapy
- Where
- Hong Kong
- Volunteers
- 18 people
- Sponsor
- Chinese University of Hong Kong
Heart Failure
Randomized Controlled Trial to Test the Efficacy of Motivational Interviewing on Self-care
Introduction: Heart failure (HF) is characterized by an increasing prevalence and burden, representing a public health problem and a major cause of morbidity and mortality.
- Trial name
- NCT05595655
- Testing
- Motivational Interviewing
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Insomnia Chronic, Shift Work Sleep Disorder
Tailored Treatment of Insomnia in Social and Health Care Sector Shift Workers in Occupational Health Care
The goal of this clinical trial is to evaluate the usefulness of cognitive behavioural therapy for insomnia (CBT-I) tailored to shift workers in the social and health care sector.
- Trial name
- Sote-VURHOT (NCT06827626)
- Testing
- Cognitive behavioral therapy for insomnia, Sleep hygiene counselling
- Where
- 4 sites in Finland
- Volunteers
- 84 people
- Sponsor
- Finnish Institute of Occupational Health
Obesity & Overweight, Weight Management
Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care
The proposed project aims to implement and evaluate a novel, family-based lifestyle medicine intervention integrating group Shared Medical Appointments (SMAs) for parents and adolescents with a twelve-month medically tailored…
- Trial name
- NCT07717658
- Testing
- Culinary medicine classes, Medically Tailored Groceries, Shared Medical Appointments
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Tufts University
Osteoarthritis, Knee
Effect of Hydrotherapy After Unilateral UKA
Osteoarthritis (OA) is a progressive disease of the synovial joints that causes joint pain and limitation of function resulting in considerable morbidity and impairment of quality of life.
- Trial name
- NCT06459960
- Testing
- Hydrotherapy, Convention
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- Chinese University of Hong Kong
Melanoma
Tailored Intervention for Melanoma Patient's Families
The purpose of the investigators' study is to find the best way to provide information about sun protection and skin cancer detection.
- Trial name
- NCT00816374
- Testing
- Reading materials and discussions, Questionnaires
- Where
- 3 sites in United States
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Acute Coronary Syndrome
Half Dose of Prasugrel and Ticagrelor in Acute Coronary Syndrome (HOPE-TAILOR)
East Asian patients will be required optimal dose of newer P2Y12 inhibitors (prasugrel or ticagrelor) to determine the safer treatment and better outcome.
- Trial name
- NCT02944123
- Testing
- Clopidogrel 75 mg, Prasugrel 5 mg, Ticagrelor 45 mg
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Dong-A University
Diet, Healthy, HbA1c
MTM2MTG Pilot Ancillary Study
The investigators will conduct an ancillary study of participants in a completed RCT of medically tailored meals to determine whether transitioning these participants to a medically tailored groceries (MTG) program is a feasible…
- Conditions
- Diet, Healthy, HbA1c, Blood Pressure
- Trial name
- MTM2MTG (NCT07620808)
- Testing
- Medically Tailored Groceries
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Columbia University
Persistent Atrial Fibrillation
Patient-TAILORed Ablation of Persistent AF Guided by Instantaneous Amplitude and Frequency Modulation Maps (TAILOR-AF)
Pulmonary vein isolation (PVI) is still considered the cornerstone of catheter ablation for patients with persistent atrial fibrillation (AF).
- Trial name
- TAILOR-AF (NCT05169320)
- Testing
- Subcutaneous implantable loop recorder (ILR) implantation, Mapping and catheter ablation, Minimally invasive surgical ablation via thoracoscopy
- Where
- 2 sites in Spain
- Volunteers
- 25 people
- Sponsor
- Hospital San Carlos, Madrid
Temporomandibular Joint Dysfunction Syndrome
Tailored Self-Management of Temporomandibular Disorders (TMD) Using Health Information Technology
The purpose of this pilot project is to determine the feasibility and acceptability of proposed methods for a subsequent clinical trial of a tailored self-management program (PACT) designed to decrease pain in participants with…
- Trial name
- TMDPACT (NCT03036215)
- Testing
- PACT Experimental Arm
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Overweight and Obesity, Pregnancy Related
Healthy Lifestyle Before and During Pregnancy to Prevent Childhood Obesity - the PRE-STORK-trial
Introduction: The prevalence of childhood overweight and obesity has risen from just 4% in 1975 to more than 18% in 2016. Little is known about adiposity of the infant, but it positively associates to the mother's BMI.
- Trial name
- NCT05578690
- Testing
- Diet, Exercise, Mentorship
- Where
- Denmark
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Sleep Disturbances
Individually Tailored Lighting System to Improve Sleep in Older Adults
In conjunction with investigators at the Cecil G. Sheps Center for Health Services Research, University of North Carolina (UNC) at Chapel Hill, we propose to develop and evaluate a low-cost, minimally obtrusive device that…
- Trial name
- NCT01855126
- Testing
- Blue light, Red light
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Rensselaer Polytechnic Institute
Heart Failure, Chronic Kidney Diseases
Kaiser Permanente Evaluation of Medically Tailored Meals in Adults With Medical Conditions at High Readmission Risk
This study is a virtual, remote, decentralized pragmatic clinical trial comparing the efficacy of medically tailored meals alone or medically tailored meals with remote nutritional counseling compared with usual standard of care…
- Conditions
- Heart Failure, Chronic Kidney Diseases, Diabetes Mellitus, Type 2
- Trial name
- KP NOURISH (NCT05166525)
- Testing
- Medically tailored meals
- Where
- 5 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Kaiser Permanente
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
MBC Physical Activity Study
This clinical trial evaluates the impact of a tailored physical activity program on physical activity in patients with breast cancer that has spread from where it first started to other places in the body (metastatic).
- Trial name
- NCT06500858
- Testing
- Exercise Intervention, Health Promotion and Education, Internet-Based Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Thomas Jefferson University
Polycystic Ovary Syndrome
Metformin Administration in Infertile Anovulatory PCOS Patients
In a recent prospective study evaluating the efficacy of 1700 mg/day metformin as first-line approach for infertile anovulatory patients with PCOS, we identified predictors for metformin efficacy.
- Trial name
- NCT00501787
- Testing
- Metformin
- Where
- Italy
- Sponsor
- University Magna Graecia
End Stage Disease
Motivational Interviewing Tailored Programme for Promoting Advance Care Planning Behaviours
This proposed study is designed to test the effects of motivational interviewing (MI) in increasing the uptake of ACP behaviours among patients with palliative care needs.
- Trial name
- NCT04162912
- Testing
- Motivational Interviewing tailored Advance Care Planning
- Where
- 2 sites in Hong Kong
- Volunteers
- 204 people
- Sponsor
- Food and Health Bureau, Hong Kong