Clinical trials: Target Controlled İnfusion
Children, Hernia, Inguinal
Comparing Inhalation and Total Intravenous Anesthesia Methods
This study compares the effects of anesthesia using target-controlled infusion (TCI) and inhalation methods on pediatric patients undergoing inguinal hernia repair.
- Trial name
- TIVA-IHA (NCT06467279)
- Testing
- Target Controlled İnfusion, Inhalation anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Shoulder Dislocation
Propofol Target-Controlled Infusion in Emergency Department Sedation
There exists continued controversy over the use of propofol in Emergency Department procedural sedation, this is despite its widespread existence in clinical practice for at least a decade.
- Trial name
- ProTEDS (NCT03442803)
- Testing
- Target-Controlled Infusion
- Where
- 4 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Blood Pressure, Hypotension
Hypotensive Effect of Anaesthesia With TCI
Hypotension will often complicate induction of anaesthesia. The investigators want to test the hypothesis that Target Controlled Infusion, as opposed to Velocity Controlled Infusion, leads to less degree of hypotension.
- Trial name
- HEAT (NCT02733406)
- Testing
- Target Controlled Infusion, Velocity Controlled Infusion
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Umeå University
Pancreatic Cancer
Evaluation of Safety of Rexin-G Gene Transfer for Advanced Pancreatic Cancer
This is a dose-seeking study that will test the safety of increasing doses of Rexin-G, given intravenously, in patients with advanced or metastatic pancreatic cancer who have failed standard chemotherapy.
- Trial name
- NCT00121745
- Testing
- Rexin-G Dose 1, Rexin-G Dose 2, Rexin-G Dose 3
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Epeius Biotechnologies
Hypotension on Induction, Hypnotic Intoxication
Mean Arterial Pressure Reduction Anesthesia Induction Using Propofol Bolus or Tritiated Target-infusion
To compare haemodynamics and bispectral index values between conventional bolus propofol induction and target-controlled propofol infusion.
- Trial name
- NCT04291794
- Testing
- Propofol, Propofol Injection [Diprivan]
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brasilia University Hospital
Target Controlled Infusion, General Anesthesia
The Application of Target Controlled Infusion of Etomidate Combined With Propofol in the Maintenance of Anesthesia During Brain Surgeries
To explore the application of target controlled infusion of etomidate combined with propofol in the maintenance of anesthesia during brain surgeries.
- Trial name
- NCT02174120
- Testing
- propofol, etomidate
- Volunteers
- 120 people
- Sponsor
- Henan Provincial People's Hospital
Hysteroscopy / Methods, Lidocaine Infusion
Targeted Lidocaine Infusion for Pain Reduction in Office Hysteroscopy
The goal of this study is to find out whether a small amount of lidocaine (a common local anesthetic) can reduce pain during office hysteroscopy - a procedure used to look inside the uterus.
- Conditions
- Hysteroscopy / Methods, Lidocaine Infusion, Placebo - Control
- Trial name
- OPTILID (NCT07318285)
- Testing
- Lidocaine %2 ampoule, Saline (0.9% NaCl)
- Volunteers
- 208 people
- Sponsor
- YAARA TABIB
Kyphoplasty, Prone Position
TCI Versus Manual TIVA for Sedation During Prone Kyphoplasty: Effects on Respiration, Recovery, and EEG
This single-center, prospective, observational study compares target-controlled infusion (TCI) versus manually administered total intravenous anesthesia (TIVA) for sedation in patients undergoing kyphoplasty in the prone…
- Conditions
- Kyphoplasty, Prone Position, Target Controlled Infusion of Propofol, End Tidal Carbon Dioxide
- Trial name
- NCT07745348
- Testing
- Target controlled infusion of propofol, non invasive ETCO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
General Anesthesia, Propofol Target-controlled Infusion
Effects of Epidural Local Anesthetics on Propofol Induction
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.
- Conditions
- General Anesthesia, Propofol Target-controlled Infusion, Thoracic Epidural Anesthesia
- Trial name
- NCT02000973
- Testing
- Lidocaine, Bupivacaine, Ropivacaine
- Volunteers
- 80 people
- Sponsor
- First Hospital of China Medical University
Emergence Delirium, Post-Operative Cognitive Dysfunction
Post Operative Cognitive Dysfunction After Oncologic Surgery
Aim of this trial is to define if Post-Operative Cognitive Dysfunction, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, and Postoperative Delirium, relate to concentration of effector's…
- Trial name
- NCT03774420
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Padova
Intravenous Drug Usage
Impact of Priming the Infusion System on the Performance of Target-controlled Infusion of Remifentanil
The investigators attempted to determine an adequate priming volume for our infusion system, and investigated the extent of a possible delay of the drug effect, that would result from mechanical defects of the infusion system…
- Trial name
- NCT01477905
- Testing
- Remi50 with prime, Remi20 with prime
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Ajou University School of Medicine
Postoperative Mechanical Ventilation Time
Study on the Effect of Target-controlled Infusion for General Anesthesia in Cardiac Surgery
The purpose of the study was to evaluate whether individualized general anesthesia with target-controlled infusion could help patients wake up early for extubation and reduce the incidence of postoperative complications, and to…
- Trial name
- NCT06012955
- Testing
- Target-controlled infusion (TCI) systems
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sedation
Sedation of Advanced Endoscopic Procedure
To evaluate the impacts of target-control infusion (TCI) and bispectral index (BIS) monitoring during advanced endoscopic procedure.
- Trial name
- NCT03172078
- Testing
- advanced endoscopic procedure
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Bispectral Index, Transcutaneous Carbon Dioxide
Compare the Side Effects and Difference Awake Level of Three TCI Propofol Formula in TVOR Patients
This study is to find the fewer side effects formula of anesthesia for TVOR patients, to compare the BIS level during emergence and to find the correlation between BIS and transcutaneous carbon dioxide concentration.
- Conditions
- Bispectral Index, Transcutaneous Carbon Dioxide, PONV, Blood Pressure
- Trial name
- NCT00760253
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Appropriate Affect, Complication of Device Insertion
Requirements of Propofol With Target Controlled Infusions for Supraglottic Airway Devices
to evaluate and compare the effect-site concentration of propofol with the TCI system for second-generation SGA device insertion between the I-gel™, Supreme™, ProSeal™ and Laryngeal Tube Suction II™.
- Trial name
- NCT04664595
- Testing
- Propofol Fresenius
- Where
- 2 sites in Thailand
- Volunteers
- 40 people
- Sponsor
- Prince of Songkla University
Anesthesia
The PROTECT Trial: PROpofol Titration to Enhance haemodynamiC sTability
The aim of this multicentre, single-blinded, expertise-based randomised controlled trial is evaluate whether slowly increasing the dose of the anaesthetic drug propofol based on a patient's needs leads to more stable blood…
- Trial name
- NCT06980688
- Testing
- Propofol titration, Conventional propofol induction
- Where
- 4 sites in Switzerland
- Volunteers
- 320 people
- Sponsor
- University Hospital, Basel, Switzerland
Propofol, Anesthesia Brain Monitoring
Effect of Midazolam Bolus on Eleveld and Schnider TCI (Target Controlled Infusion) Models
No trials have evaluated the effect of a Midazolam bolus (routinely used for premedication before general anesthesia) on the Concnetration at the effector site of Propofol (CeP) of Eleveld and Schnider TCI models, routinely used…
- Trial name
- TCI (NCT05800288)
- Testing
- Propofol
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova
Pediatric Patients, Cardiology
A Comparison Of The Effect Of Target-Controlled Infusion Anesthesia And Inhalation Anesthesia
A total of 70 patients who underwent angiographic examination, ASD closure, VSD closure, PDA closure and aortic balloon dilatation were included in this study.
- Trial name
- NCT06265610
- Testing
- TIVA/TCI
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cardiac Surgery
Low Remifentanil Target Controlled Infusions for Cardiac Surgery
The development of target effect-site controlled concentrations (TCI) of remifentanil have gained increasing acceptance during cardiac surgery as regarding the resulting of hemodynamic stability and early extubation.
- Trial name
- NCT02033629
- Testing
- Ce 1 ng/ml, Ce 2 ng/ml, Ce 3 ng/ml
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Sedation, Endoscopy
Propofol Administered by Gastroenterologists by Target Controlled Infusion Pump During Endoscopy
Many studies address safety of non-anesthesiologist propofol sedation (NAPS) for gastrointestinal endoscopy. Target Controlled Infusion (TCI) is a sophisticated tool for providing optimal sedation regimen and avoiding under or…
- Trial name
- Propofol TCI (NCT02062177)
- Testing
- Propofol, Midazolam
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Università Vita-Salute San Raffaele