Clinical trials: Taste, Altered
Epilepsy
An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray.
This study will assess long-term safety and tolerability of repeat dose diazepam nasal spray in adolescents and adults with cluster seizures, with a focus on potential local effects (changes in nasal mucosa, olfaction, and taste).
- Trial name
- NCT02316847
- Testing
- diazepam nasal spray
- Where
- 33 sites in United States
- Volunteers
- 126 people
- Sponsor
- Acorda Therapeutics
Diet Habit, Diet Modification
Interaction of Salivary Proteins and Polyphenols
Participants will be chosen through an initial sensory test to find high and low-perceivers of astringency. Selected participants will drink a chocolate milk or milk substitute beverage for one week each with washout weeks in…
- Conditions
- Diet Habit, Diet Modification, Taste, Altered, Saliva Altered
- Trial name
- NCT03501238
- Testing
- Chocolate Milk, Chocolate milk substitute, Chocolate milk substitute with gelatin
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Purdue University
Dysphagia, Stroke
Changes in Sensitivity, Taste and Smell in Stroke Patients
This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients.
- Trial name
- 5S (NCT03240965)
- Testing
- FEES (flexible endoscopic evaluation of swallowing), Sensitivity threshold, Taste-/smell-test
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Multiple Myeloma
LI-TASTE Study: Light for Taste
Rationale: In 2020, 115,000 Dutch patients were diagnosed with cancer. Up to 85% of patients treated with radiotherapy involving the head and neck, chemotherapy or stem-celltransplantation (SCT) suffer from taste disorders…
- Trial name
- LI-TASTE (NCT06258096)
- Testing
- LX2.3 Laser and LED Photobiomodulation System
- Volunteers
- 52 people
- Sponsor
- Academic Centre for Dentistry in Amsterdam
Pancreatic Cancer
Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma
NutriCa65-PDAC is a clinical study for patients aged 65 years or older with pancreatic ductal adenocarcinoma, a type of pancreatic cancer.
- Trial name
- NutriCa65-PDAC (NCT07821554)
- Testing
- Experimental: Personalised nutritional care delivered by a trained dietitian
- Where
- 5 sites in Denmark, Italy and 3 more
- Volunteers
- 250 people
- Sponsor
- Inna Chen, MD
Acute Otitis Media
Taste Changes in Acute Otitis Media
Detection of taste changes in Acute Otitis Media (AOM) patients.
- Trial name
- NCT03315156
- Testing
- Electrogustometery
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Taste Alterations, Smell Disorder
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents
Childhood cancer is a serious and life-changing disease that affects thousands of children every year worldwide. In addition to the disease itself, cancer treatments such as chemotherapy often cause difficult side effects.
- Conditions
- Taste Alterations, Smell Disorder, Eating Behavior Changes
- Trial name
- QUALISENS (NCT07490093)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Leon Berard
Prostate Carcinoma
Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy
This clinical trial studies whether cooling the mouth with popsicles (oral cryotherapy) decreases taste changes in prostate cancer patients receiving taxane chemotherapy.
- Trial name
- NCT07218718
- Testing
- Best Practice, Oral Cryotherapy, Survey Administration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- City of Hope Medical Center
Diet, Healthy, Obesity
Olfactory and Taste Changes During Fasting Mimicking Diet (FMD)
Literature experiences demonstrated the impact of medically-assisted pulsed fasting on olfactory behavior in both the animal and human models and - conversely - the lack of homogeneous results linked - up to now - to…
- Conditions
- Diet, Healthy, Obesity, Olfaction Disorders
- Trial name
- FMD1 (NCT04529161)
- Testing
- Fasting Mimicking Diet (FMD), Routinary diet habits
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Uniter Onlus
PCOS, Semaglutide
The Effects of Semaglutide on Taste, Tongue Tissue Transcriptome, Gastric Emptying and Central Neural Response in Women With PCOS and Obesity
The purpose of the study is to explore the effects of GLP-1 receptor agonist (GLP-1 RA) semaglutide on modulation of taste sensitivity, tongue tissue transcriptome, modulation of neural response in central reward processing…
- Conditions
- PCOS, Semaglutide, Taste, Altered, Tongue Tissue Transcriptome
- Trial name
- NCT04263415
- Testing
- Semaglutide
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Saliva Altered, Taste, Altered
Taste Perception, Salivary Proteins & the Oral Microbiome
Genetic differences in taste are believed to play an important role in food selection, especially for strong-tasting foods and beverages.
- Trial name
- NCT04107688
- Testing
- Control, CPE
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Taste, Altered, Xerostomia
An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer
Taste problems and xerostomia (dry mouth) are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life.
- Conditions
- Taste, Altered, Xerostomia, Neoplasms
- Trial name
- NCT06287294
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Our Lady's Hospice and Care Services
Gingivitis, Periodontitis
The Impact of Non-surgical Periodontal Therapy on Patients' Halitosis, Taste Perception, and Smell Sensation
The goal of this observational study is to evaluate the effect of non-surgical periodontal treatment on patient halitosis, smell, and taste perception in gingivitis and periodontitis patients.
- Trial name
- NCT06063460
- Testing
- Periodontal examination, baseline questionnaire about sociodemographic characteristics, smoking habits, oral hygiene habits, halitosis, smell and taste perception, phase I periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Necmettin Erbakan University