Clinical trials: Tear
Partial-Thickness Rotator Cuff Tear
Injection Therapies for Partial Rotator Cuff Tears
This completed study compared four injection treatments in patients with painful partial tears of the rotator cuff, the tendons that help move and stabilize the shoulder.
- Trial name
- NCT07871695
- Testing
- Autologous Platelet-Rich Plasma (PRP), Dextrose 15%, Betamethasone Sodium Phosphate and Betamethasone Acetate
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Rotator Cuff Tears, Rotator Cuff Injuries
Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study)
Treatment of rotator cuff tears with micro-fragmented adipose tissue is a minimal-invasive procedure with the potential to shorten and ease recovery, accelerate return to daily activity and work of thus with a potential capacity…
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Tear Arthropathy
- Trial name
- NCT06505135
- Testing
- Stem-cell treatment, Standard care
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Anterior Cruciate Ligament (ACL) Tear
Bone-Patellar Tendon-Bone Versus Quadriceps Tendon Autograft for Anterior Cruciate Ligament Reconstruction: A Non-Inferiority Trial Regarding Anterior Knee Pain
This prospective, randomized, single-center, non-inferiority clinical trial will compare anterior knee pain (AKP) after primary anterior cruciate ligament (ACL) reconstruction using either a bone-patellar tendon-bone autograft…
- Trial name
- BTB vs QT (NCT07846709)
- Testing
- Bone-Patellar Tendon-Bone Autograft ACL Reconstruction, Quadriceps Tendon Autograft ACL Reconstruction
- Volunteers
- 150 people
- Sponsor
- Hospital del Mar
Rotator Cuff Tears (RCTs)
SINEFIX-2022 Pilot Phase
Shoulder pain is one of the most commonly reported musculoskeletal complaints, which negatively affects upper limb use, night rest, daily life activities, work, sports performance and autonomy.
- Trial name
- NCT05721560
- Testing
- Rotator cuff repair with the SINEFIX
- Where
- Germany
- Volunteers
- 9 people
- Sponsor
- BAAT Medical Products B.V.
Rotator Cuff Tears
Intravenous Versus Intra-articular Tranexamic Acid for Visual Clarity During Arthroscopic Rotator Cuff Repair
This single-center, prospective, randomized, double-blind controlled trial evaluated whether intravenous (IV) or intra-articular (IA) administration of tranexamic acid (TXA) improves intraoperative visual clarity, compared with a…
- Trial name
- NCT07686705
- Testing
- Tranexamic acid (intra-articular), Tranexamic acid (intravenous)
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Konkuk University Medical Center
Meniscus Tear
Novel Bioactive Sleeve on Pain and PROMs
A novel bioactive sleeve will be compared to a placebo sleeve with a similar look and feel to assess pain outcomes, patient reported outcome measures, and effectiveness of healing based on range of motion.
- Trial name
- NCT06041321
- Testing
- Reparel Sleeve
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Rotator Cuff Tears, Rotator Cuff Injuries
Fibrin Clot Augmentation in Arthroscopic Rotator Cuff Repair
The aim of this study is to evaluate whether applying an autologous fibrin clot to the repair site improves tendon healing and clinical outcomes after arthroscopic rotator cuff repair.
- Trial name
- NCT07853950
- Testing
- Arthroscopic Rotator Cuff Repair, Autologous Fibrin Clot
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ataturk University
Rotator Cuff Tear, Sling
Patient Education and Sling Use After Shoulder Surgery
This study will evaluate whether educational pamphlets can help patients safely manage personal hygiene, household activities, and female-specific self-care while wearing a sling after surgery.
- Conditions
- Rotator Cuff Tear, Sling, Shoulder Pain
- Trial name
- NCT07851233
- Testing
- Control - Standard Postoperative Education, Intervention - Living with a Sling Educational Pamphlets
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Rotator Cuff Tears, Postoperative Pain Management
Pain Education After Rotator Cuff Surgery
Study Title: The Effect of Pain Neuroscience Education Combined with Conventional Rehabilitation on Pain Management and Functional Outcomes in Patients Undergoing Mini-Open Rotator Cuff Repair Purpose: This study aims to…
- Conditions
- Rotator Cuff Tears, Postoperative Pain Management, Shoulder Dysfunction, Kinesiophobia (Fear of Movement)
- Trial name
- PNE-RCS (NCT06886932)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Elif Dilara Durmaz
Rotator Cuff Tears, Shoulder Pain
Effect of Kinesio Taping After Rotator Cuff Surgery
This prospective randomized controlled trial evaluated whether adding Kinesio Taping (KT) to a standardized postoperative rehabilitation program improves early clinical recovery after arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Shoulder Pain, Post Operative Pain
- Trial name
- RCR-KT (NCT07375927)
- Testing
- Kinesio Taping, Standard Postoperative Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Olcay Yavuz
Rotator Cuff Tears, Rotator Cuff Injuries
Repeated Injections of Adipose-derived Stem Cells in Rotator Cuff Tears
The aim of the project is to investigate whether repeated implantations of micro-fragmented adipose tissue (MFAT), into the shoulder muscle can improve the outcome of standard surgical treatment for rotator cuff tears (RCT).
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Stem Cells
- Trial name
- NCT07592936
- Testing
- Adipose derived stem cell injection
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries
Over-the-Top vs. Anteromedial ACLR With Lateral Extraarticular Tenodesis
This study aims to compare the over-the-top (OTT) anterior cruciate ligament (ACL) reconstruction (ACL-R) technique with the anteromedial ACL-R + lateral extraarticular tenodesis (LET).
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Tear
- Trial name
- NCT06664047
- Testing
- OTT ACLR, ACLR LET
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Ankara City Hospital Bilkent
Tear Disorder, Resectable Locally Advanced Non-Squamous NSCLC
A Prospective Trial Evaluating the Efficacy and Tumor Immune Microenvironment Remodeling Induced by SFI Plus PD-1 Inhibitors and PBC in Resectable NSCLC
This prospective, single-center clinical trial will enroll 30 treatment-naïve patients with locally advanced, resectable stage II-IIIA non-small cell lung cancer (NSCLC) to receive neoadjuvant Shenqi Fuzheng Injection (SFI) in…
- Trial name
- SFI-NSCLC (NCT07843251)
- Testing
- Shenqi Fuzheng Injection
- Volunteers
- 30 people
- Sponsor
- Anhui Provincial Cancer Hospital
Knee Osteoarthritis, Knee Injuries
Dronabinol After Arthroscopic Surgery
The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee.
- Conditions
- Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee
- Trial name
- NCT05335252
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Dehiscence Wound, Secondary Perineal Tear
Conservative Treatment or Resuturing Among Women With Perineal Wound Dehiscence After Vaginal Labour
The goal of this observational study is to make us more aware of the short and long-term outcomes for women having an uncomplicated healing process after a rupture or birth cut in the perineum after giving birth in relation to a…
- Conditions
- Dehiscence Wound, Secondary Perineal Tear, Episiotomy; Dehiscence
- Trial name
- HEAL (NCT06026423)
- Testing
- Clinical examination and pictures, Questionnaire
- Where
- Denmark
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Meniscus Tear, Tibial, Meniscus Lesion
JuggerStitch Post Market Clinical Follow-up Study
This study is a post-market follow-up study. The data collected from this study will serve the purpose of confirming the safety and performance of the JuggerStitch Device used for meniscal repair according to the product…
- Trial name
- NCT04228367
- Testing
- JuggerStitch Meniscal Repair Device
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 103 people
- Sponsor
- Zimmer Biomet
Rotator Cuff Injuries, Rotator Cuff Tear
Ultrasound and Shear Wave Elastography for Assessment of the Quality of Rotator Cuff Muscles
Rotator cuff disorders are among the most frequent musculoskeletal causes of shoulder pain, weakness, and limited movement. In many individuals with rotator cuff disease, the damaged muscles gradually shrink (muscle atrophy) and…
- Conditions
- Rotator Cuff Injuries, Rotator Cuff Tear, Muscular Atrophy, Fatty Infiltration
- Trial name
- NCT07837583
- Volunteers
- 70 people
- Sponsor
- Assiut University
Rotator Cuff Tear, Telemedecine
Remote App-based Rehabilitation After Rotator Cuff Repair
The aim of this study was to evaluate the effectiveness of a mobile application for telemedicine in patients recovering from arthroscopic rotator cuff tendon repair.
- Conditions
- Rotator Cuff Tear, Telemedecine, Rotator Cuff Injuries
- Trial name
- NCT07555704
- Testing
- Telerehabilitation, Conventional home exercise program
- Where
- Vietnam
- Volunteers
- 102 people
- Sponsor
- Hanoi Medical University
ACL Tear
Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing
There is no consensus regarding the best surgical management of primary ACL tears. Recent evidence suggests that internal brace augmentation may increase load failure and therefore stabilize the graft in-situ at the time of ACL…
- Trial name
- NCT05532189
- Testing
- ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Anterior Cruciate Ligament Tear
Therapeutic Benefits of a Motor Imaging Protocol Following Anterior Cruciate Ligament Reconstruction Surgery
The purpose of this study is to compare changes in lower limb symmetry during functional and strength tests, before and after the motor imagery program, in patients who received the 3-week motor imagery program starting 3 months…
- Trial name
- IMAGERIEMOTR (NCT07210489)
- Testing
- Reconstructive surgery after anterior cruciate ligament rupture, sessions from a physical therapist
- Where
- France
- Volunteers
- 70 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche