Clinical trials: Tear Disorder
Meniscus Disorder, Meniscus; Degeneration
Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment
The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment
- Conditions
- Meniscus Disorder, Meniscus; Degeneration, Meniscus Tear, Meniscus Lesion
- Trial name
- NCT05882591
- Testing
- Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment by the means of published technique (reference nr 1).
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
Knee Arthritis, Shoulder Arthritis
Efficacy of Intra-articular NSAID Versus Corticosteroid in the Treatment of Shoulder and Knee Conditions: A Randomized, Double-Blind, Prospective Study
The proposed study will compare the efficacy of Triamcinolone versus Ketorolac for intra-articular injection of the knee and shoulder
- Conditions
- Knee Arthritis, Shoulder Arthritis, Shoulder Impingement, Meniscus Lesion
- Trial name
- NCT03616340
- Testing
- Shoulder injection, knee injection
- Volunteers
- 50 people
- Sponsor
- OSF Healthcare System
Premature Rupture of Membrane
Fetal and Maternal Outcome in Preterm Premature Rupture of Membranes (PPROM)
The aim of this study is to compare fetal and maternal outcome in cases of PPROM before 34 weeks versus after 34 weeks.
- Trial name
- NCT03491826
- Testing
- rupture of membrane
- Where
- Egypt
- Volunteers
- 1,011 people
- Sponsor
- sarah mohamed hassan
Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy
Intralesional Versus Perilesional 5% Dextrose Injection in Partial Rotator Cuff Tears
This prospective, randomized, double-blind controlled clinical trial aims to compare the clinical and ultrasonographic outcomes of intralesional and perilesional 5% dextrose injection in patients with partial rotator cuff tears.
- Conditions
- Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy, Shoulder Pain Chronic, Supraspinatus Tendon Tear
- Trial name
- NCT07688902
- Testing
- Intralesional 5% Dextrose Injection, Perilesional 5% Dextrose Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Dry Eye Disease (DED)
The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function
The purpose of this research study is to evaluate the effects of trehalose, an ingredient found in commercially available artificial tears, on the corneal barrier function.
- Trial name
- NCT06655441
- Testing
- 3% trehalose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Allergic Conjunctivitis
Sea Water in Allergic Conjunctivitis
Background and purpose: Allergic conjunctivitis has increased alarmingly in recent years. The objectives of the study are: 1) To establish the safety and efficacy of applying eyewashes in spray form as monotherapy on the symptoms…
- Trial name
- NCT04695795
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Biceps Tendon Disorder, Tendinosis
Restoring the Anatomic Tension Relationship of the Long Head of the Biceps During Tenodesis
The goal of this clinical trial is to determine the clinical impact of restoring the anatomic-tension relationship of the long head of the biceps (LHB) when performing a biceps tenotomy and tenodesis.
- Conditions
- Biceps Tendon Disorder, Tendinosis, Rotator Cuff Injuries
- Trial name
- NCT06571695
- Testing
- Anatomic Long Head of Biceps Tensioning Technique, Traditional Long Head of Biceps Tensioning Technique
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Loyola University
Radius Fractures, Colles' Fracture
Repair vs Non-repair of the Pronator Quadratus Muscle in Distal Radius Fractures. RCT.
The purpose of this study is to determine the functional outcome of repairing the pronator quadratus (PQ) muscle in subjects operated for a distal radius fracture (DRF) with volar locked plating.
- Conditions
- Radius Fractures, Colles' Fracture, Rupture of Muscle, Arm Injuries
- Trial name
- NCT02348437
- Testing
- Repair, Non-repair
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Nordsjaellands Hospital
Chronic Hip Joint Pain, Prearthritic Hip Disease
Movement Pattern Training in People With Intra-articular, Prearthritic Hip Disorders
Intra-articular, prearthritic hip disorders (PAHD) result in substantial dysfunction in young adults and are proposed precursors to hip osteoarthritis (OA).
- Trial name
- NCT02913222
- Testing
- Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Washington University School of Medicine
Children Born to Mothers Enrolled in the TOCOPROM Trial
6-year Outcomes in Children After Nifedipine vs Placebo for Preterm Prelabor Rupture of Membranes at 22-33 Weeks
The purpose of this study is to evaluate the neurodevelopment at age 6 of children born to women with preterm prelabor rupture of membranes at 22 to 33 weeks of gestation, after antenatal exposure to nifedipine vs placebo.
- Trial name
- TOCOKIDS (NCT07146451)
- Testing
- Self-administered parental questionnaire, A short psychological assessment performed online
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Cancer
Concentration of S-1 Metabolites in Tear and Plasma of Patients Receiving TS-1
S-1 has been also shown to be an effective drug for palliative chemotherapy in Eastern and Western GC patients. Recently, some case and small-sized studies have been reported on lacrimal drainage obstruction(LDO)caused by…
- Trial name
- NCT01621919
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Bundang Hospital
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, Abdominal Aortic Aneurysm Without Rupture
Shockwave™Peripheral Intravascular Lithotripsy Balloon for Advanced Endovascular Aortic Repair
Shockwave TEVAR is a nonrandomized, prospective, international, multi-center, PMCF, obervational study. The aim of this study is to evaluate the outcomes of the Shockwave™ Peripheral Intravascular Lithotripsy Balloon (Shockwave…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, Abdominal Aortic Aneurysm Without Rupture, Thoracic Aortic Aneurysm Without Rupture
- Trial name
- TEVAR (NCT06332911)
- Testing
- Shockwave™ Peripheral Intravascular Lithotripsy Balloon M5+
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 30 people
- Sponsor
- Rede Optimus Hospitalar SA
Keratoconjunctivitis Sicca
Effect of Controlled Adverse Environment (CAE) on Tear Film Stability
The purpose of this study is to evaluate the effect of the controlled adverse environment (CAE) on Mean Break-Up Area in subjects diagnosed with Dry Eye Syndrome.
- Trial name
- NCT01547936
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- ORA, Inc.
Preterm Premature Rupture of Membrane
Predictive Value of Maternal Serum Pentraxin 3 (PTX 3) and Heparin-binding Protein (HBP) for Chorioamnionitis in Preterm Premature Rupture of Membranes
Objective: The aim of this study was to investigate the predictive value of maternal serum pentraxin 3 (PTX3) and heparin-binding protein (HBP) for chorioamnionitis in preterm premature rupture of membranes (PPROM).
- Trial name
- NCT05207800
- Testing
- The concentrations of PTX3 and HBP were monitored in maternal blood, placental tissue and amniotic fluid.
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Dry Eye
Prostaglandin Analog Eyelash Serum and Ocular Surface Health: A Prospective Study
This prospective interventional study investigates the effects of a prostaglandin analog-based eyelash serum on ocular surface integrity, tear film stability, and eyelash growth over six weeks.
- Trial name
- EYESERUM (NCT06875687)
- Testing
- Prostaglandin Analog-Based Eyelash Serum
- Where
- Spain
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Seville
Dry Eye Disease
Evaluating the Efficacy of Dry Eye (DE) Disease Treatment Using Novel Tear Film Imager (TFI)
Dry Eye disease signs and symptoms are reduced in patients who receive topical steroids and topical hyaluronic acid. AdOM's Tear Film Imager measurements are reproducible and it can diagnose the dry eye disease state in a single…
- Trial name
- NCT04670263
- Testing
- Tear Film Imager
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Adom Advanced Optical Technologies Ltd.
Laceration, Abscess
Nitrous Oxide Use in Minor Procedures
Title: High-concentration continuous flow nitrous oxide use for procedural-induced pain or anxiety during pediatric minor procedures.
- Trial name
- NCT01911351
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Parturition
Perineal Echography in the Delivery Room for the Detection of Anal Lesions
The main objective of this study is to compare the rate of anal incontinence (measured by the Wexner score, qualitative and quantitative (> 4)) at 3 months post partum among primiparas with vaginal tears ≥ 2nd degree who receive…
- Trial name
- OASIS 1 (NCT01320995)
- Testing
- Perineal ultrasound
- Where
- 2 sites in France
- Volunteers
- 111 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Meniscus Tear
The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis
This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears.
- Trial name
- NCT06532851
- Testing
- Progressive Resistance Exercise (PRE), Aerobic Exercise, Control
- Where
- 2 sites in Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Androgen Deficiency, Ocular Surface Disease
The Effects of Androgen Replacement Therapy on Tear Osmolarity and Ocular Surface Parameters in Androgen Deficiency
Objective: To evaluate tear osmolarity and ocular surface findings in men with androgen deficiency (AD) and assess changes after androgen replacement therapy (ART). Design: A prospective interventional study.
- Conditions
- Androgen Deficiency, Ocular Surface Disease, Tear Osmolarity
- Trial name
- EffAndonOS (NCT07168265)
- Testing
- androgen replacement therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Neon Hospital