Clinical trials: Teenagers
Infections, Papillomavirus
Immunogenicity and Safety of GSK Biologicals' HPV Vaccine 580299 in Healthy Japanese Females 10-15 Years of Age
Human papillomavirus (HPV) infection has been established as a necessary cause of cervical cancer. GSK Biologicals has developed an HPV vaccine (580299) which targets the 2 most common oncogenic HPV types (HPV-16 and HPV-18)…
- Trial name
- NCT00492544
- Testing
- Cervarix™ (HPV-16/18 L1 VLP AS04)
- Where
- 5 sites in Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Maxillary Transverse Deficiency (Posterior Crossbite) in Early Adolescent Patients
Posterior Resin Bite Turbos Effect on Maxillary Expansion Using a HYRAX Expander in Early Adolescents
This randomized controlled clinical trial aims to evaluate the effect of posterior disarticulatory resin bite turbos on the rate of maxillary expansion using a HYRAX expander in early adolescent patients.
- Trial name
- HYRAX_ RME_SME (NCT07739498)
- Testing
- Intervention 1: HYRAX expander with posterior disarticulatory resin bite turbos, Intervention 2 (Control): HYRAX expander alone
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Mansoura University
Teenage Pregnancy
LeadHer, a Gender-specific Teen Pregnancy Prevention Curriculum for Girls 15-19
Alternatives For Girls (AFG) is offering LeadHer as a gender-specific teen pregnancy prevention curriculum to girls between the ages of 14-19 years old who live in Wayne County, MI.
- Trial name
- NCT03265314
- Testing
- LeadHer, Sassy Science
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Alternatives For Girls
Youth Engagement
Strengthening Healthy Relationships Among Apsaalooke Youth
This pilot project uses community based participatory research principles to build upon cultural strengths to develop a feasibility of intervention to promote relationality and connectedness among Apsáalooke youth.
- Trial name
- NCT05734014
- Testing
- Connectedness Activities
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montana State University
Anxiety, Depression
Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents
This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.
- Conditions
- Anxiety, Depression, Emotional Disorder, Autism
- Trial name
- NCT05738967
- Testing
- Transdiagnostic cognitive behavioral therapy (CBT), Treatment as usual
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Baylor College of Medicine
Type 1 Diabetes, Obesity
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for complications.
- Trial name
- NCT05414409
- Testing
- Metformin
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Heba M. Ismail
Functional Gastrointestinal Disorders
Defining Adolescent Nausea Through Brain Imaging and Neurostimulation Response
This study evaluates the efficacy of auricular neurostimulation via an non-invasive percutaneous electrical nerve field stimulator (PENFS) in adolescents with functional nausea.
- Trial name
- NCT03675321
- Testing
- Active Auricular Neurostimulation
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Depression
Evaluation of the H1-Coil TMS- Double Blind Placebo Controlled Study in Adolescent Patients Suffering From Major Depression
This study is a randomized double blind placebo controlled EEG monitored study of deep rTMS treatment to treat adolescent depression.
- Trial name
- NCT03541707
- Testing
- Deep TMS Brainsway's H coil
- Where
- Israel
- Volunteers
- 52 people
- Sponsor
- Shalvata Mental Health Center
HIV/AIDS, HSV-2 Infection
The Impact of VCT and Condom Distribution as HIV Prevention Strategies Among Youth in Kenya
The vast majority of new HIV infections occur in sub-Saharan Africa, where nearly 2 million people become infected with HIV/AIDS every year.
- Trial name
- NCT03868644
- Testing
- Voluntary Counseling and Testing for HIV (VCT), Condoms
- Volunteers
- 10,646 people
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Peanut Allergy
Safety of MOON101 for the Treatment of Peanut Allergy
The goal of this open-label, single escalating dose study in 3 sequential groups: adults, adolescents, and children with peanut allergy is to assess the safety of MOON101. The main question it aims to answer is: 1.
- Trial name
- SURVEYOR (NCT07580898)
- Testing
- Dose A, Dose B, Dose C
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Moonlight Therapeutics, Inc.
Depression Disorders, HIV (Human Immunodeficiency Virus)
Improving the Treatment of Depression Among Youth With HIV
Depression is a common psychiatric condition among Youth with HIV (YWH), with prevalence as high as 25% in the United States. The treatment of depression is essential for improving both psychiatric and medical outcomes for YWH…
- Trial name
- NCT07211087
- Testing
- COMBEX, COMB
- Volunteers
- 130 people
- Sponsor
- Rhode Island Hospital
Childhood Obesity, Adolescent Obesity
Local Proof of Concept of Evira in Abu Dhabi Study
Evira is a digital treatment tool developed for treatment of childhood obesity. Through daily weighings at home using a special scale together with a message function in the Evira application, parents and the clinicians can…
- Conditions
- Childhood Obesity, Adolescent Obesity, Treatment Adherence
- Trial name
- NCT06665893
- Testing
- Digi-physical treatment tool
- Where
- United Arab Emirates
- Volunteers
- 70 people
- Sponsor
- Sheikh Shakhbout Medical City
Pharyngitis, Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults
To determine if a single 2.0-g dose of azithromycin SR is at least as effective as a 3-day course of azithromycin (500 mg once daily for 3 days) when used to treat adolescents and adults with strep throat, and to assess efficacy…
- Trial name
- NCT00644293
- Testing
- azithromycin (Zithromax), azithromycin SR
- Where
- 59 sites in United States, Belgium and 8 more
- Volunteers
- 598 people
- Sponsor
- Pfizer
Childhood Obesity, Overweight and Obesity
Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
The main purpose of the present study is to perform a 10 weeks dietary intervention study with a follow-up for 52 weeks in children from 7-14 years of age with overweight or obesity.
- Conditions
- Childhood Obesity, Overweight and Obesity, Adolescent Obesity, Adolescent Overweight
- Trial name
- COPE (NCT04522921)
- Testing
- Diet with a higher amount of protein (25E% per day), Increased follow-up contact after the 10-week intervention, Diet with a lower amount of protein (15E% per day)
- Where
- 2 sites in Denmark
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Gingival Inflammation
Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents
To evaluate the effect of probiotics supplied in two different forms (dairy products containing probiotics as yogurt and freeze-dried synthetic probiotics sachets) on improving gingival condition and caries potentiality of dental…
- Trial name
- NCT03640065
- Testing
- freeze-dried probiotic sachets, fermented dairy product ( yogurt)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mental Health, Addictions
Better Access to and Integration of Mental Health and Addiction Services Through Navigation: A Mixed-Methods Adaptive Pragmatic Clinical Trial
The Family Navigation Project (FNP), a youth and family mental health and addictions (MHA) navigation service that currently operates in the Greater Toronto Area (GTA), is expanding to northern Ontario by setting up a new site in…
- Conditions
- Mental Health, Addictions, Patient Navigation, Health Services
- Trial name
- BEAM (NCT07707492)
- Testing
- Family Navigation Project
- Where
- 2 sites in Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Obese Adolescents, Mental Health
Co-creating School Community Intervention Program on Physical Activity to Increase Health Equity in Children and Adolescents
The goal of this observational and interventional study is to understand whether environmental and behavioral interventions can improve physical activity and health outcomes in children aged 12-16 years attending VDU Atžalynas…
- Trial name
- Connection (NCT07120516)
- Where
- Lithuania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sandra Andrusaityte
Cyberbullying, Grooming
Wise Interventions in the Digital Society
This study evaluates the effectiveness of a Wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) in Spanish adolescents and young people.
- Conditions
- Cyberbullying, Grooming, Risk Behavior
- Trial name
- NCT04497506
- Testing
- Wise Intervention (Self-affirmation and Incremental theory of personality), Standard preventive intervention
- Where
- Spain
- Volunteers
- 1,212 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Dementia Alzheimers
Assessing an Intergenerational Music Program Delivered by Adolescents to Older Adults With Declining Cognition
Intergenerational music programming has been shown to benefit both young people and older adults in terms of quality of life, social connection, and promotion of positive cross-age attitudes.
- Trial name
- NCT04645017
- Testing
- Intergenerational Music Program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
Behavior, Adolescent, Childhood Obesity
In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes
The aim of this study is to look at changes in diabetes-related risk factors in Black adolescent girls who are at risk for type 2 diabetes and their primary female caregiver after both participating in a 12-week in-person…
- Conditions
- Behavior, Adolescent, Childhood Obesity, Diabetes Mellitus, Type 2, Pediatric Obesity
- Trial name
- BGW In-Person (NCT06557317)
- Testing
- Black Girls for Wellness In-Person
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cornell University
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