Clinical trials: Teenagers
Healthy Participants
Prevention of Hazardous Use of Alcohol with Danish High School Students (Our Choice)
The trial 'Our Choice' examines the effect of two prevention interventions targeting school, parent, and student levels at Danish high schools.
- Trial name
- NCT06018389
- Testing
- Structural only, Structural+Group MI
- Where
- Denmark
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Patellofemoral Pain Syndrome, Knee Pain
5 Year Follow-up of Adolescents With Knee Pain
The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown.
- Trial name
- NCT02873143
- Testing
- No intervention
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Underage Drinking
Facilitating Adolescent Self-Change for Alcohol Problems
This present multi-site investigation compares a voluntary brief intervention for adolescent alcohol problems to an educational comparison condition.
- Trial name
- NCT01690026
- Testing
- Motivation interviewing based brief intervention, Standard Intervention
- Where
- 3 sites in United States
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Rhinitis, Allergic, Perennial
A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis
The purpose of this study is to assess long-term ocular safety of fluticasone furoate nasal spray in adult and adolescent subjects diagnosed with perennial allergic rhinitis.
- Trial name
- NCT00682643
- Testing
- fluticasone furoate nasal spray
- Where
- 56 sites in United States
- Volunteers
- 550 people
- Sponsor
- GlaxoSmithKline
Grief, Bereavement
Adolescent Bereavement Initiative in the Free State, South Africa
Coping with Loss is a randomized controlled trial to assess the effectiveness of a bereavement intervention targeting female adolescents who have experienced the death of someone important in their lives.
- Trial name
- NCT02368808
- Testing
- Abangane Support Group
- Volunteers
- 843 people
- Sponsor
- Tulane University School of Social Work
HIV Infections
Safety and Efficacy of Dolutegravir/Lamivudine (DTG/3TC) in Therapy-naive Human Immunodeficiency Virus-1 (HIV-1) Infected Adolescents
First-line antiretroviral regimens are highly efficacious and generally well tolerated. However, as these regimens need to be taken life-long, there is growing concern about long-term toxicities associated with these regimens.
- Trial name
- NCT03682848
- Testing
- DTG + 3TC FDC
- Where
- 8 sites in Kenya, South Africa and 1 more
- Volunteers
- 32 people
- Sponsor
- ViiV Healthcare
Stress, Health Promotion
The Effects of Pythagorean Self-Awareness Intervention on Young Adolescents in Primary School-Α One Arm Clinical Trial
In this one arm clinical trial, students of the 6th grade in a primary school participated in the PSAI for 8 weeks. Self-report questionnaires and hair cortisol concentrations were used for the evaluation of the aforementioned…
- Conditions
- Stress, Health Promotion, Adolescence
- Trial name
- NCT04824326
- Testing
- PSAI-CA
- Where
- Greece
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Atopic Dermatitis
A Study to Evaluate the Efficacy and Safety of SIM0718 in Adult and Adolescent Patients With Moderate to Severe Atopic Dermatitis
This study will evaluate the efficacy and safety of SIM0718 in adolescents (12- < 18 years) and adults (18-75 years) with moderate to severe AD.
- Trial name
- NCT06477835
- Testing
- SIM0718 Injection
- Where
- China
- Volunteers
- 259 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd
Psychosis, Prodromal Schizophrenia
Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability…
- Conditions
- Psychosis, Prodromal Schizophrenia, Prodromal Symptoms
- Trial name
- SCORES (NCT05131035)
- Testing
- SCORES (Specific COgnitive Remediation with Support)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Pertussis (Whooping Cough), Diphtheria
A Phase II Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents)
the immunogenicity and safety of different dosages of adsorbed acellular pertussis (two-component) diphtheria-tetanus combined vaccine
- Conditions
- Pertussis (Whooping Cough), Diphtheria, Tetanus
- Trial name
- NCT07894055
- Testing
- Tdap vaccine
- Where
- China
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Obesity, GERD
Pharmacokinetics of Pantoprazole and CYP2C19 Activity in Children and Adolescents With GERD: A Pilot Study
The World Health Organization has declared childhood obesity to be "one of the most serious public health challenges of the 21st century," (http://www.who.int/dietphysicalactivity/childhood).
- Trial name
- NCT01887743
- Testing
- Pantoprazole
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Substance Use
Health and Resilience Projects: Foundations
The Health and Resilience Project (HARP): Foundations is investigating the efficacy of the Strong African American Families (SAAF) intervention in promoting the health and well being of African American adolescents.
- Trial name
- HARP-F (NCT05253235)
- Testing
- SAAF, Receipt of parenting book
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Pectus Excavatum, Pectus Excavatum Deformity
The Effects of Schroth Based Exercise Therapy in Adolescents with Pectus Excavatum
Research on exercise methods for pectus excavatum (PE) is limited, highlighting the need for further studies. This study investigated the effects of Schroth-based exercise therapy combined with vacuum treatment in 35 adolescents…
- Conditions
- Pectus Excavatum, Pectus Excavatum Deformity, Funnel Chest, Chest Deformities
- Trial name
- NCT06763406
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Hacettepe University
Hand Strength
Measurement of Handgrip Strength and Pinch of Children and Adolescents Using an Electronic Dynamometer
This study has quantified the hand strength in movements of handgrip and pinch with electronic dynamometer.
- Trial name
- NCT03463447
- Testing
- Electronic Dynamometer, Hydraulic dynamometer
- Where
- Brazil
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Mogi das Cruzes
Assessment of Depression, Anxiety and ADHD Among Children and Adolescents With Congenital Heart Disease
Assessment of Depression, Anxiety and ADHD Among Children and Adolescents With Congenital Heart Disease.
Congenital heart disease (CHD) is the most common birth defect, affecting ∼1% of all live births.The spectrum of CHD is wide, ranging from simple (not requiring immediate or possibly any surgical intervention) to severe or…
- Trial name
- Psychiatricy (NCT06836076)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Depression
Depression Prevention Program for Adolescents
This study will compare the effectiveness of two programs designed to prevent depression in adolescents.
- Trial name
- NCT00183417
- Testing
- Cognitive behavior therapy (CBT), Supportive/expressive (S/E) therapy, Bibliotherapy
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Substance Use Disorders, Parenting
PURPOSE: A Social Media Intervention for Parent Support
The purpose of this study is to develop and test a social media-based (Facebook) intervention that provides support and skills to parents with adolescent children in treatment for substance abuse.
- Trial name
- NCT02629068
- Testing
- PURPOSE
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
C3 Glomerulopathy (C3G), Primary Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN), Recurrent Glomerular Disease After Kidney Transplantation
A Study to Assess the Efficacy and Safety of Pegcetacoplan for the Prevention of Recurrent C3G or Primary IC-MPGN in Kidney Transplant Recipients
To assess the efficacy and safety of pegcetacoplan for the prevention of recurrent C3G or primary IC-MPGN in kidney transplant recipients
- Trial name
- PRESERVE (NCT07898774)
- Testing
- Pegcetacoplan
- Where
- 33 sites in Brazil, Canada and 8 more
- Volunteers
- 30 people
- Sponsor
- Swedish Orphan Biovitrum
Diabetes Mellitus, Type 1
Safety And Efficacy Of Exubera Compared With Subcutaneous Human Insulin Therapy In Children And Adolescents
To assess the safety and efficacy of Exubera on pulmonary function and glycemic control in subjects ages 6-17 over a 1 year period.
- Trial name
- NCT00479258
- Testing
- Inhaled insulin (Exubera), Subcutaneous Insulin (subject's prescribed)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Pfizer
Scoliosis
Ghrelin Resistance in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic Scoliosis (AIS) is the most common spine pathology. It is opposed to secondary scoliosis due to chronic diseases. Many hypotheses have been made to elucidate the origin of this illness.
- Trial name
- NCT02829476
- Testing
- Osteoblast sample
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Toulouse
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