Clinical trials: Teenagers
Acute Lymphoblastic Leukaemia
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
The ALL SCTped 2012 FORUM is a multinational, multi-centre, controlled, prospective phase III study for the therapy and therapy optimisation for children and adolescents with ALL in complete morphological remission (CR, less than…
- Trial name
- NCT01949129
- Testing
- VP16, TBI, Thiotepa
- Where
- 119 sites in Argentina, Australia and 29 more
- Volunteers
- 1,800 people
- Sponsor
- St. Anna Kinderkrebsforschung
Anemia
Multiple Micronutrient Supplementation With Digital Layering Among Adolescents in Tanzania
This study is a three-arm, individually randomized controlled trial evaluating the impact of digitally delivered nutrition education, layered onto multiple micronutrient supplementation (MMS), on anemia and related health…
- Trial name
- MMSDigitalTZ (NCT07493772)
- Testing
- Behavioral: SMS Intervention (Intervention Arm I), Behavioral: In Person Digital Arm (Intervention Arm II)
- Where
- Tanzania
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Eating Disorders
Comparing the Effectiveness of Two Therapies to Treat Signs of Anorexia Nervosa in Adolescents
This study will compare the effectiveness of two therapies to treat early signs of anorexia nervosa in adolescents.
- Trial name
- NCT00418977
- Testing
- Family-Based Therapy ("Maudsley Method"), Individual Supportive Psychotherapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Suicide, Suicide Attempt
Eco-anxiety and Suicide
Suicide is a major public health problem. About 9,000 suicides per year are retrieved by year in France. Between 15,000 and 20,0000 suicide attempts give rise to contact with the healthcare system.
- Conditions
- Suicide, Suicide Attempt, Suicidal, Anxiety
- Trial name
- EcoAnx (NCT05707975)
- Testing
- Identifying a relationship between the intensity of eco-anxiety and the severity of suicide risk in adolescents
- Where
- France
- Volunteers
- 261 people
- Sponsor
- Hospices Civils de Lyon
Basketball Shooting Performance, Cognitive-Motor Dual-Task Performance
Motor Imagery Training and Shooting Performance in Adolescent Basketball Players
This randomized controlled trial evaluated the effects of an eight-week motor imagery training program on shooting performance in adolescent basketball players under single-task and cognitive-motor dual-task conditions.
- Conditions
- Basketball Shooting Performance, Cognitive-Motor Dual-Task Performance, Motor Imagery
- Trial name
- NCT07798843
- Testing
- PETTLEP-Based Motor Imagery Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uludag University
Solid Tumors, Children
A Prospective, Single-arm Clinical Study of Liposomal Mitoxantrone Combination Regimen in the Treatment of Relapsed and Refractory Solid Tumors in Children, Adolescents and Young Adults
The aim of this clinical study is to determine the efficacy and safety of the liposomal mitoxantrone combination regimen in treating relapsed and refractory solid tumors among children, adolescents, and young adults.
- Conditions
- Solid Tumors, Children, Adolescents
- Trial name
- NCT06761417
- Testing
- Mitoxantrone liposome, Capecitabine, Anlotinib
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Antibiotic Associated Diarrhea, Clostridium Difficile Infection
Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children
The purpose of this study is to determine if the daily intake of the probiotic Lactobacillus reuteri prevents antibiotic-associated diarrhoea and related Clostridium difficile infections in children and adolescents.
- Conditions
- Antibiotic Associated Diarrhea, Clostridium Difficile Infection, Gastroenteritis
- Trial name
- AADreuter (NCT01295918)
- Testing
- L reuteri in children on antibiotics
- Where
- 2 sites in Bulgaria
- Volunteers
- 100 people
- Sponsor
- St Marina University Hospital, Varna, Bulgaria
Lupus
Improving Quality of Life for African American Female Adolescents With Lupus
This study will evaluate a program designed to help African American adolescents with lupus (systemic lupus erythematosus or SLE) cope with the disease.
- Trial name
- NCT00068874
- Testing
- Coping skills and cognitive restructuring techniques, Educational training
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Medical University of South Carolina
Flat Foot; Spastic
To Evaluate the Efficiency and Results of Adding BFR to the Physical Therapy Program fo Managing Adolescents Presented With Spasmotic Flatfoot Deformities Compared to the Standard Physical Therapy Program Without BFR
The goal of this randomized clinical trial is to evaluate the efficiency and results of adding blood flow restriction (BFR) training to the physical therapy program for managing adolescents presented with spasmotic flatfoot…
- Trial name
- BFR SFFD (NCT07343752)
- Testing
- blood flow restriction
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Intervention, Waitlist Control
Web-Based Body Image Intervention for Coaches of Adolescent Girls - Pilot
According to the World Health Organization, only 15% of 11-17-year-old girls meet the recommended daily physical movement guidelines (e.g., 60-minutes per day).
- Trial name
- NCT05316558
- Testing
- Body Confident Coaching
- Where
- United Kingdom
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Functional Abdominal Pain Syndrome
Brain Mechanisms of Attention and Pain in Youth With FAPD
The objectives of this study are to identify neural mechanisms of increased pain in pediatric FAPD and examine mechanisms of disrupted attention in the presence of induced pain.
- Trial name
- NCT05892055
- Testing
- MRI Procedure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michigan State University
Fish Allergy
Allergy Against Different Species of Fish in Children and Adolescents Allergic to Fish
Study hypothesis: Some children and adolescents with fish allergy can tolerate eating some species of fish Purpose of the study: The purpose of this study is to determine to which degree fish allergic children and adolescents can…
- Trial name
- TRO-FAST (NCT02365168)
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- University Hospital of North Norway
Substance Abuse, Post-partum Depression
Cradling Our Future Through Family Strengthening Study
The purpose of this study is to determine whether an in-home, paraprofessional-delivered family strengthening curriculum entitled Family Spirit is effective at increasing parental competence, improving maternal outcomes and…
- Conditions
- Substance Abuse, Post-partum Depression, Depression
- Trial name
- NCT00373750
- Testing
- Family Spirit Intervention
- Where
- 5 sites in United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Scoliosis Idiopathic, Scoliosis; Adolescence
Postoperative Rehabilitation or Mobilization After Scoliosis Surgery
Scoliosis surgery is a major surgery associated with postoperative pain, loss of physical function and pulmonary dysfunction in adolescent idiopathic scoliosis patients (AIS).Despite the advanced, various medical treatment…
- Trial name
- NCT04403152
- Testing
- Post-operative rehabilitation, Post-operative mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Epilepsy
An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray.
This study will assess long-term safety and tolerability of repeat dose diazepam nasal spray in adolescents and adults with cluster seizures, with a focus on potential local effects (changes in nasal mucosa, olfaction, and taste).
- Trial name
- NCT02316847
- Testing
- diazepam nasal spray
- Where
- 33 sites in United States
- Volunteers
- 126 people
- Sponsor
- Acorda Therapeutics
Sarcoma, Soft Tissue
a Multicenter Clinical Trial for the Treatment of Children and Adolescents With Soft Tissue Sarcoma Stage 4
Phase II Study to evaluate the response on two blocks of topotecan and carboplatin
- Trial name
- NCT00130858
- Testing
- Topotecan, Carboplatin
- Where
- 38 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Cooperative Weichteilsarkom Study Group
PTSD, Substance Use Disorder (SUD)
Adolescent Stress and Substance Intervention Subsequent to Trauma
The long-term goal of this study is to address the adoption of the new trauma center requirement to establish best practices of screening for acute stress with an intervention to prevent both adolescent PTSD and substance use.
- Conditions
- PTSD, Substance Use Disorder (SUD), Acute Stress Disorder
- Trial name
- ASSIST (NCT07197476)
- Testing
- ASSIST Video Intervention
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Teen Pregnancy Prevention
Evaluation of Stepping Stones
The goal of this randomized trial is to learn if the Stepping Stones (StSt) intervention has a positive impact on the sexual health and relationship behaviors of sexually active youth between the ages of 12 and 22 years old who…
- Trial name
- StSt (NCT06574217)
- Testing
- Stepping Stones (StSt), Like
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The Policy & Research Group
HIV Infections
Directly Observed Therapy for HIV Infected Adolescents
Adherence to a doctor-prescribed anti-HIV drug regimen is crucial in the management of HIV infection. In previous studies with tuberculosis patients, directly observed therapy (DOT), a strategy in which patients are observed…
- Trial name
- NCT00259389
- Testing
- Directly observed therapy (DOT)
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Randomized, Placebo-Controlled, Multidose, Study Comparing Generic Budesonide/Formoterol Fumarate Dihydrate to Symbicort® in Asthmatic Participants
This study has a randomized multiple-dose, placebo-controlled, parallel group design consisting of a 2-week open placebo Run-in Period followed by a 6-week Treatment Period with placebo, test product (budesonide 80 microgram…
- Trial name
- NCT02495168
- Testing
- Generic Budesonide/Formoterol Fumarate Dihydrate, Symbicort® (Budesonide/Formoterol Fumarate Dihydrate)
- Where
- 17 sites in United States
- Volunteers
- 1,714 people
- Sponsor
- Actavis Inc.
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