Clinical trials: Teenagers
Osteogenesis Imperfecta (OI)
A Dose REgimen-Finding Study of AGA2115 in Chinese Patients With Osteogenesis ImpeRfecta (EIR)
This study is to evaluate the safety and efficacy of AGA2115 at three different dose regimens in Chinese adults and adolescents with Type I, III, or IV Osteogenesis imperfecta (OI).
- Trial name
- EIR (NCT07557446)
- Testing
- AGA2115
- Where
- 5 sites in China
- Volunteers
- 48 people
- Sponsor
- Angitia Biopharmaceuticals Guangzhou Limited
Menstrual Cycle Abnormal
The Impact of Whole-Body Vibration and Relaxation Techniques on Adolescent Athlete Girls With Triad Syndrome"
This study aims to explore the effects of Whole-Body Vibration (WBV) exercises and relaxation techniques on adolescent female athletes who are experiencing Female Athlete Triad Syndrome - a condition that may include low bone…
- Trial name
- WBV for triad (NCT07587346)
- Testing
- whole body vibration device, relaxation training
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MTI University
Caffeine, Insufficient Sleep
Consequences of Caffeine Intake in Sleep Restricted Teenagers
The goal of this clinical trial is to systematically investigate two prominent factors in teenagers' daily life: Caffeine and sleep restriction (SR) and their combined influence on sleep, cognition, and behavior in healthy…
- Trial name
- NCT05790161
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Psychiatric Hospital of the University of Basel
Mental Disorder, Depressive Symptoms
Module-Based Psychological (MBP) for Community Youths
This waitlist, randomised controlled trial (RCT) aims to examine the effectiveness of the Module-Based Psychological (MBP) intervention in reducing mental distress for youths aged 12-30 years in Hong Kong.
- Conditions
- Mental Disorder, Depressive Symptoms, Anxiety Symptoms
- Trial name
- MBP_RCT (NCT06005961)
- Testing
- Module-Based Psychological (MBP) Intervention
- Where
- Hong Kong
- Volunteers
- 400 people
- Sponsor
- The University of Hong Kong
Alcohol Abuse, Tobacco Use Disorder
Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking
The goal of this project is to evaluate the feasibility, acceptability, and effect size of a new computerized Motivational Enhancement Therapy (cMET) intervention for alcohol-involved adolescents in primary care.
- Conditions
- Alcohol Abuse, Tobacco Use Disorder, Substance Use
- Trial name
- NCT01881841
- Testing
- cMET
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Boston Children's Hospital
Stress, Psychological
Gratitude Interventions for Academic Stress Among Pakistani Adolescents
The experimental nature of this study will provide the empirical data in analyzing the effectiveness of gratitude exercises which later can be adapted in stress reduction programs at school level.
- Trial name
- NCT05640505
- Testing
- School based Gratitude Interventions
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- University of Malaya
Type 2 Diabetes
TODAY2 Phase 2 Follow-up
The primary objective of T2P2 is to track the progression of T2D and related comorbidities and complications in the TODAY cohort as they transition to young adulthood.
- Trial name
- T2P2 (NCT02310724)
- Testing
- TODAY cohort
- Where
- 15 sites in United States
- Volunteers
- 517 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Mental Health Literacy
Web-based Mental Health Literacy Program
Mental health literacy is a concept that aims to improve the skills of individuals to overcome difficulties in providing the appropriate help they need in this area.
- Trial name
- NCT04597996
- Testing
- web based education for students
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
HIV-infection/Aids
Healthy Teen Girls: HIV Risk Reduction
This project assesses the efficacy of an HIV prevention program with adolescent females incarcerated in the Mississippi training school for girls.
- Trial name
- NCT00787696
- Testing
- Cognitive-behavioral HIV/STD risk reduction
- Where
- United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Mississippi State University
Obesity, Adolescent, PreDiabetes
Unsweetened Sparkling Water and Changes in Sweetness Perception in Adolescents
The study design is a prospective observational study in adolescents who are at risk for developing Type 2 Diabetes (T2D), to evaluate the effectiveness of sparkling water to reduce dietary intake of added sugars and thereby…
- Trial name
- NCT05966870
- Testing
- Unsweetened flavored sparkling water
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Indiana University
Tobacco Use Behavior
Smoking Prevention Through Social Connections Among Adolescents - ASPIRE
The central hypothesis of this study is that the addition of social influence strategies to a web-based program called ASPIRE will boost its success in lowering intention to use tobacco among adolescents and experiencing stronger…
- Trial name
- NCT02703597
- Testing
- Surveys, ASPIRE, GSA-ASPIRE-Network
- Where
- United States
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Florida
Mental Health Issue
Provision of Service of a YQL Programme For Youth Smokers
This project is funded by Department of Health. We will run a quitline which provides telephone smoking cessation counseling to youth smokers aged 25 or below.
- Trial name
- NCT05148520
- Testing
- 5A's model
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Mental Disorders
Transdiagnostic Treatment for Early Stage Mental Health Problems in Youth
The aim of this pilot study is to examine a brief manualized treatment, Emotional Regulation Group Skills Training (ERG ST), which has shown promise with high-risk youth presenting with a range of mental health concerns.
- Trial name
- NCT02540746
- Testing
- ERG Skills Training, Motivational Enhancement, Family Skills Training
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- St. Joseph's Healthcare Hamilton
mHealth Intervention
Technology-Based Resources to Increase Uptake of Sexual Health Services for Teens
Alone time with healthcare providers is vital for adolescents, as recommended by several professional organizations, as it enhances health service utilization, empowers adolescents to manage their health, and facilitates…
- Trial name
- TRUST (NCT07064070)
- Testing
- TRUST
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Adolescent Idiopathic Scoliosis, Respiratory Depression
Anesthetic Optimization in Scoliosis Surgery
The standard anesthetic care plan for people having adolescent idiopathic scoliosis surgery will be accompanied by a pharmacokinetic simulation of the administered drugs to suggest opportunities to adjust drug doses to achieve…
- Conditions
- Adolescent Idiopathic Scoliosis, Respiratory Depression, Postoperative Pain
- Trial name
- AIS (NCT02481570)
- Testing
- pharmacokinetic simulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Hypospadia, Phimosis
Intelligence Changes Following Minor Surgery
Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted.
- Conditions
- Hypospadia, Phimosis, Inguinal Hernia
- Trial name
- NCT01483313
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- RenJi Hospital
Adolescent, Foot Posture Index Score
Relationship Between Foot Posture, Toe Flexor Strength, and Balance in Adolescents
The foot plays a critical role in movement and postural control, with toe flexor strength linked to gait, performance, and stability. While these relationships are well studied in adults, evidence in adolescents is limited.
- Conditions
- Adolescent, Foot Posture Index Score, Toe Flexor Strength, Flat Foot Acquired Bilateral (Pes Planus)
- Trial name
- NCT07132424
- Testing
- Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Kültür University
Type 1 Diabetes Mellitus
Check It! Positive Psychology Intervention to Improve Adherence in Adolescents With T1D
Problems with diabetes management in adolescents with type 1 diabetes are common - occurring at rates as high as 93% - and have serious health consequences, including poor blood sugar control and risk for later complications.
- Trial name
- NCT02746627
- Testing
- Positive Affect, Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Acne
Efficacy of Cosmetic Product RV3278B-OS0386 on Skin Surface Ecosystem, in Teenagers with Mild to Moderate Facial Acne
The aim of this exploratory study is to better understand the mechanisms of action of the RV3278B-OS0386 cosmetic product on the cutaneous ecosystem, in acne context.
- Trial name
- NCT06659861
- Testing
- RV3278B-OS0386, RV4632A-RY1845
- Where
- Romania
- Volunteers
- 52 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Diphtheria, Tetanus
Study of BK1301 (DTaP Vaccine) as a Booster in Adolescents
This study is designed to assess the immunogenicity and safety of DTaP vaccine (BK1301) as a booster dose in adolescents. The purposes of this study are as follows: To confirm the non-inferiority of BK1301 to Adsorbed…
- Conditions
- Diphtheria, Tetanus, Pertussis
- Trial name
- NCT02118961
- Testing
- Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed (DTaP vaccine, BK1301), Adsorbed Diphtheria-Tetanus Combined Toxoid (DT toxoid)
- Where
- 7 sites in Japan
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma Corporation
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