Clinical trials: Teenagers
Asthma
A Safety Extension Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Asthmatic Adults and Adolescents on Inhaled Corticosteroid Plus LABA
The purpose of this study is to characterize the safety profile of benralizumab administration in asthma patients who have completed one of the three predecessor studies: D3250C00017, D3250C00018 or D3250C00020.
- Trial name
- BORA (NCT02258542)
- Testing
- Benralizumab
- Where
- 429 sites in United States, Argentina and 22 more
- Volunteers
- 2,133 people
- Sponsor
- AstraZeneca
Hereditary Angioedema (HAE), Angioedema
Expanded Access for the Prevention of Acute Attacks of 1) Hereditary Angioedema (HAE) in Children and 2) Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH) in Teenagers and Adults
The expanded access program allows people to gain access to an unlicensed treatment on compassionate grounds. Lanadelumab, also known as TAK-743, is a medicine to help prevent angioedema attacks.
- Trial name
- NCT04583007
- Testing
- Lanadelumab 150 mg, Lanadelumab 300 mg
- Where
- 20 sites in United States, Canada and 3 more
- Sponsor
- Shire
ADHD
The Efficacy of Cathodal tDCS in ADHD
The purpose of this study is to investigate the effectiveness of five sessions of cathodal tDCS over the left DLPFC on inhibitory control/response inhibition in children and adolescents with ADHD.
- Trial name
- NCT03955692
- Testing
- tDCS
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Mahidol University
Medication Adherence, HIV Drug Resistance
Sustainable Adherence and Prevention of HIV Drug Resistance in Adolescents
The overall goal of this study is to determine if implementation of a package of interventions that includes DBS-based VL monitoring, coupled with an evidence-based intervention to improve ART adherence using cognitive-behavioral…
- Trial name
- SAPHRA (NCT03928834)
- Testing
- Adapted Nzira Itsva
- Where
- Zimbabwe
- Sponsor
- University of Zimbabwe
Childhood Cancer Survivors
Physical Activity Post-Cancer for Adolescents and Young Adults
The Physical Activity Post-Cancer for Adolescents and Young Adults (PAPAYA) trial aims to carry out a pilot randomized controlled trial among 10-17 year-old adolescents and young adults, at least 1 year and up to 5 years…
- Trial name
- PAPAYA (NCT04947709)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Adolescent, Depression - Major Depressive Disorder
Efficacy and Mechanism of Transcranial Temporal Interference Stimulation (tTIS) in the Treatment of Adolescent Depression
This trial is a single-center, single-blind, randomized, sham-stimulation controlled clinical trial. The primary objective of the trial is to detect the targeted effect of tTIS on the nucleus accumbens of adolescent depression…
- Trial name
- NCT06902064
- Testing
- Transcranial temporal interference stimulation
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Mental Health Impairment
Pharmacogenetic Supported Prescribing in Kids
Implementation of pharmacogenetic testing for children and adolescents aged 6-24 who are starting or changing psychiatric medication.
- Trial name
- PGx-SParK (NCT04797364)
- Testing
- Pharmacogenetic Testing
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- University of Calgary
Obesity
Overweight, Quality of Life and Psychological Difficulties in Teenagers
Obesity is a major public heath issue. It may have various impacts on a patient's life by causing psychological problems, altering a patient's quality of life,etc.
- Trial name
- QOL-ADOB (NCT02417909)
- Testing
- questionnaires about quality of life
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Head Injury Trauma
A Meditation Intervention on Subconcussive Head Impacts
The purpose of this research is to explore potential methods of rehabilitating changes observed from repetitive head impacts. Participation in this study will involve functional magnetic resonance (fMRI) imaging, aerobic testing…
- Trial name
- NCT04225663
- Testing
- Guided Meditation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Nonsuicidal Self-Injury, Self-Harm
Internet-delivered Emotion Regulation Individual Therapy or Adolescents (IERITA) With Self-injury Within Child and Adolescent Mental Health Services
The overall purpose of the study is to implement and evaluate IERITA (Internet-delivered Emotion Regulation Individual Therapy for Adolescents) within child and adolescent mental health services for adolescents engaging in…
- Trial name
- NCT07573085
- Testing
- Adaptable IERITA, Standard IERITA, Treatment as usual
- Where
- Sweden
- Volunteers
- 341 people
- Sponsor
- Karolinska Institutet
E-cigarette Use, Vaping
Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping
The dramatic increase in the use of e-cigarettes among U.S. adolescents has been called a national epidemic, with more adolescents now using e-cigarettes than traditional cigarettes.
- Trial name
- V2V (NCT05140915)
- Testing
- Peer Messaging, Peer Coaching via Text, Gamification
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Sickle Cell Disease
Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition Program
Sickle cell disease (SCD) is a debilitating genetic disorder affecting 70,000-100,000 Americans. It is frequently associated with very serious medical complications.
- Trial name
- NCT01569971
- Testing
- Assessment
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Opioid Misuse
A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health Centers
This study's specific aims were to: develop a digital intervention as a prevention intervention through focus groups with 40 youth; pilot-test the developed digital intervention with 30 adolescents, using methods from the…
- Trial name
- NCT04109599
- Testing
- PlaySmart, PlaySmart Storyline, Play Smart Mini-Game
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Yale University
Nasopharyngeal Carcinoma
Late Sequelae of Childhood and Adolescent Nasopharyngeal Carcinoma Survivors After Radiotherapy
Although children and adolescents are more likely to have advanced disease at onset, they generally have a significantly better chance of survival.
- Trial name
- NCT03398980
- Testing
- survivors treated with CRT
- Volunteers
- 94 people
- Sponsor
- Yuan-hong Gao
Gender Dysphoria, Adolescent
Counseling Among Gender Diverse Adolescents Who Use Depot Medroxyprogesterone
Recommendations regarding contraceptive counseling and reproductive health differ amongst transgender and gender diverse (TGD) youth compared to cis-gender youth.
- Trial name
- NCT05726903
- Testing
- Depo-subQ Provera Injectable Product
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mental Stress
The Effectiveness of Mental Wellness Youth Hubs in Hong Kong
This study sets out to evaluate (i) whether the model in phase two can improve symptoms, quality of life, functioning, and psychological outcomes in young people utilising the hub services (n = 600) compared to those in the…
- Trial name
- NCT06868303
- Testing
- LevelMind@JC Mental Wellness Youth Hubs, New Life Psychiatric Rehabilitation Association electronic clinic for psychological service, Integrated Community Centres for Mental Wellness
- Where
- Hong Kong
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Adolescent Behavior, Adolescent - Emotional Problem
Teachers Leading the Front Lines - Adolescent
Purpose: The purpose of this research is to pilot test a novel, alternative, potentially sustainable system of teacher-delivered, task-shifted adolescent mental health care.
- Conditions
- Adolescent Behavior, Adolescent - Emotional Problem, Mental Health Issue, Psychosocial Functioning
- Trial name
- TeaLeaf-A (NCT06248203)
- Testing
- Tealeaf-Mansik Swasta (Tealeaf) as adapted for Adolescents, Enhanced Usual Care (EUC)
- Where
- India
- Volunteers
- 216 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
Modifying (Phase I) and Evaluating (Phase II) Virtual Reality Job Interview Training for Youth in Transition
The unemployment rate is quite high among adults with an autism spectrum disorder (ASD). Inadequate transition planning during high school and gaps between vocational needs and availability of evidence-based services help explain…
- Trial name
- NCT03514134
- Testing
- Virtual Reality Job Interview Training, Services as Usual
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Michigan
Tooth Discoloration
Tooth Bleaching for Young Patients Using a Hydrogen Peroxide-based Gel
The aim of the present study was to evaluate colorimetric changes and tooth sensitivity in young patients submitted to tooth bleaching with 20% and 35% hydrogen peroxide.
- Trial name
- NCT02414464
- Testing
- 35% hydrogen peroxide, 20% hydrogen peroxide
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Type 1 Diabetes
The Effects of Different Exercise Modalities in Adolescents With Type 1 Diabetes Using AID Systems
Objective: The overall objective of this study is to assess the efficacy of the current recommended guidelines for physical activity (PA) in response to acute moderate intensity continous exercise (MICE) and high intensity…
- Trial name
- MODE2022 (NCT05619198)
- Testing
- High Intensity Interval Exercise, Moderate Intensity Continous Exercise
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Steno Diabetes Center Copenhagen
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