Clinical trials: Teeth Extraction, open to volunteers
Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction
THBC/CGF for Alveolar Bone Regeneration: A Real-World Study
This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted
- Trial name
- NCT07779421
- Testing
- Temperature-sensitive hydroxybutyl chitosan-loaded concentrated growth factor, Temperature-sensitive hydroxybutyl chitosan, Autologous Concentrated Growth Factor
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Tooth Extraction Site Healing
Socket Preservation Using Autogenous Dentin
Tooth extraction leads to a substantial reduction in alveolar bone volume, with up to 25% loss within the first year and up to 40-60% within three years.
- Trial name
- SPAD (NCT07608289)
- Testing
- Tooth extraction left to heal spontaneously, Tooth extraction plus collagen sponge, Tooth extraction plus tricalcium phosphate
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- University of Ostrava
Dental Anxiety, Mandibular Third Molar
Virtual Reality to Reduce Anxiety in Adults Having Lower Wisdom Tooth Surgery
This randomized controlled trial will evaluate whether immersive virtual reality can reduce anxiety in adults undergoing surgical removal of mandibular third molars under local anesthesia.
- Trial name
- NCT07853014
- Testing
- Immersive Virtual Reality (Meta Quest 3)
- Where
- Vietnam
- Volunteers
- 120 people
- Sponsor
- Hanoi Medical University
Tooth Extraction Site Healing, Alveolar Ridge Preservation
Biomaterials Exposed to Oral Environment: Which One is the Appropriate Option?
After tooth extraction, bone loss can compromise future dental implant treatment. Dentists often use biomaterials to preserve bone, but in many cases these materials are left exposed to the oral environment, where saliva and…
- Trial name
- NCT07589751
- Testing
- Alveolar Ridge Reconstruction
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Stomatognatic, Tooth Diseases
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Background: The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery.
- Conditions
- Stomatognatic, Tooth Diseases, Diseases, Tooth
- Trial name
- NCT01805869
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Impacted Third Molar Tooth
Local Metformin Gel and Impacted Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT06975839
- Testing
- Metformin, non metformin gel
- Volunteers
- 36 people
- Sponsor
- Fayoum University
Odontectomy (Tooth Extraction), Socket Preservation and Healing Following Simple, Non-surgical Extraction
Evaluating The Use of CGF Plugs in Fresh Odontectomy Socket.
This study evaluates the use of Concentrated Growth Factor (CGF) plugs-a third-generation healing material made from the patient's own blood-to improve recovery after simple tooth extractions.
- Conditions
- Odontectomy (Tooth Extraction), Socket Preservation and Healing Following Simple, Non-surgical Extraction, Alveolar Bone Density and Postoperative Pain Management, Periapical Radiolucency
- Trial name
- CGF (NCT07542795)
- Testing
- Concentrated Growth Factor (CGF) Plug
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
PRF
Topical Application of PRF Before Radiation Therapy
The primary goal of this study is to observe whether PRP promotes the wound healing before a radiation therapy or not, compared to the natural healing of a tooth extraction socket.
- Trial name
- PRF (NCT06406530)
- Testing
- PRF, Natural Healing
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- University of Giessen
Acute Postoperative Pain, Dental Pain
A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction
The primary objective of this trial is to assess the safety and tolerability of single, ascending doses of CYT-1010 in healthy male and female volunteers and in the treatment of acute postoperative pain after third molar…
- Trial name
- NCT07905105
- Testing
- CYT-1010
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cytogel Pharma, LLC
Pulp Exposure, Dental, Deep Dental Caries
Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study
The effect of selective caries cleaning and total caries cleaning on pulp health and post operative pain in teeth with deep caries will be investigated.
- Trial name
- NCT07041905
- Testing
- Total Caries Removal, Selective Caries Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Cukurova University
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Acute Post Operative Pain, Third Molar Extraction Surgery
A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction
The study will test the investigational product gel against placebo (which contains no active ingredient) to determine if it is safe after wisdom tooth extraction. The main questions the study will answer are: 1.
- Trial name
- NCT06864884
- Testing
- ARC-001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Arcato Laboratories, Inc.
Dental Anxiety in Children, Pain Perception
Evaluation of Virtual Reality Based Distraction on Anxiety and Pain Perception in Paediatric Dental Extraction
The goal of this clinical trial is to learn if virtual reality distraction can reduce dental anxiety and pain perception in children aged 6-10 years undergoing simple dental extraction.
- Trial name
- VR-PED (NCT07693764)
- Testing
- Virtual reality headset, Audio-visual distraction with 2D cartoons, Tell-show-do with verbal distraction
- Where
- 2 sites in Oman
- Volunteers
- 168 people
- Sponsor
- Sultan Qaboos University
Alveolar Bone Grafting, Bone Healing
Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation
The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width…
- Conditions
- Alveolar Bone Grafting, Bone Healing, Tooth Extraction Site Healing, Wound Healing
- Trial name
- NCT06624982
- Testing
- observational study
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marquette University