Clinical trials: Teeth Sensitivity
Discolored Teeth
Effect of Prophylaxis Pastes With and Without Desensitizing Agents Prior to In-office Bleaching
To evaluate the effect of prophylaxis pastes with and without desensitizing agents prior to in-office bleaching on color change and tooth sensitivity.
- Trial name
- NCT07770373
- Testing
- Treatment
- Volunteers
- 38 people
- Sponsor
- Cairo University
Dentin Sensitivity
Evaluation of the Safety and Tolerability of KH001 in Dentin Hypersensitivity Patients
This is a phase 1/2a study in dentin hypersensitivity patients to assess the safety, tolerability, efficacy and pharmacokinetics of single and multiple doses of KH001.
- Trial name
- NCT04804514
- Testing
- KH001
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- HysensBio Co., Ltd
Dentin Sensitivity, Dentin Hypersensitivity
Efficacy of a Sonic Toothbrush and 8% Arginine Toothpaste in Reducing Dentinal Hypersensitivity
This clinical study evaluates the efficacy of an oral hygiene regimen consisting of an electric sonic toothbrush used in combination with an 8.0% arginine and calcium carbonate toothpaste in reducing dentinal hypersensitivity…
- Trial name
- NCT07871786
- Testing
- 8.0% Arginine Dentifrice, Electric Sonic Toothbrush, Adult Soft Bristle Manual Toothbrush
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Colgate Palmolive
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Placebo and Post-bleaching Sensitivity
Purpose: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT03065673
- Testing
- Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Flavia Pardo Salata Nahsan
Dentin Sensitivity
The Desensitizing Treatment Effects of the Laser and Ozone on Dentin Hypersensitivity: In-vivo Comparison
The goal of this split mouth clinical trial is to compare clinical efficacy of diode laser and gas ozone in the treatment of dentine hypersensitivity (DHS) of non-carious-cervical lesion.
- Trial name
- NCT05853523
- Testing
- Gas ozone, Diode laser and desensitized gel
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- University of L'Aquila
Gingival Recession
Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm®
The purpose of the study is to evaluate whether clinical parameters for Puros Dermis are, at minimum, equivalent when compared to AlloDerm, the current industry standard, for the treatment of single, non-adjacent Miller's Class I…
- Trial name
- NCT00881959
- Testing
- Puros® Dermis versus Alloderm®
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Zimmer Biomet
Inflammation
Anti-inflammatory Steroids in the Prevention of Tooth Sensitivity
Clinical randomized, triple-blind, used to measure the level of tooth sensitivity on volunteers using a modified virtual analog scale (VAS).
- Trial name
- NCT02956070
- Testing
- Dexamethasone acetate, Potassium Nitrate
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dentin Hypersensitivity
The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.
- Trial name
- NCT04887181
- Testing
- Teethmate Desensitizer, Gluma Desensitizer, Hybrid Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Dentin Sensitivity
Effect of Glutaraldehyde on Dentin Hypersensitivity After Non-surgical Periodontal Treatment
This randomized, placebo-controlled, triple-blind trial aims to evaluate the effect of glutaraldehyde associated or not with 37% phosphoric acid conditioning on dentin hypersensitivity reduction after non-surgical periodontal…
- Trial name
- NCT04207450
- Testing
- Phosphoric Acid 37% + Solução aquosa de glutaraldeído a 5%
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dental Pulp Disease, Endodontically Treated Teeth
Post Operative Sensitivity of MTA Obturation
The aim of this study was to investigate the difference in postoperative pain caused by different root canal sealers in patients with irreversible pulpitis symptoms and no apical lesions.
- Conditions
- Dental Pulp Disease, Endodontically Treated Teeth, Endodontic Disease
- Trial name
- NCT06795282
- Testing
- MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hypomineralization Molar Incisor
Laser Therapy and Flouride Therapy in Desensibilization Hypomineralized Teeth
To investigate the efficacy of laser therapy associated with fluorotherapy in the desensibitization of hypomineralized teeth in children 8 to 12 years of age. A randomized blinded clinical trial will be conducted.
- Trial name
- LTAFTIDHT (NCT03823170)
- Testing
- Laser therapy, Fluorotherapy, Laser therapy and Fluorotherapy
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universidade Ceuma
Dentin Sensitivity
To Evaluate the Efficacy of an Experimental Dissolvable Strip in Rapidly Relieving Dentinal Hypersensitivity (DH)
A proof of principle single-centre, randomized-controlled, examiner-blind, two treatment group study to investigate the efficacy of an experimental 15% w/w dissolvable strip in relieving dentine hypersensitivity (DH) after a…
- Trial name
- NCT02937623
- Testing
- Dissolvable polymer strip containing Novamin (calcium sodium phosphosilicate)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Comparison of Post-Operative Sensitivity of 5th Genaration Bonding Agent With 8th Generation Bonding Agent in Class1 Composite Restoration
The goal of this randomized clinical trial is to compare post-operative sensitivity after Class I composite restorations using 5th-generation and 8th-generation bonding agents in adults aged 18 to 50 years.
- Trial name
- NCT07862270
- Testing
- 5th generation bonding agent, 8th generation bonding agent
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Rehman Medical Institute - RMI
Dentin Hypersensitivity
Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study
Here's the revised version with the corrected treatment and follow-up session schedule: --- The aim of this clinical trial is to evaluate the effectiveness of bioactive toothpastes, desensitizing agents, and Er-YAG laser…
- Trial name
- NCT06854068
- Testing
- laser treatment, application of desensitizing agent
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Dentin Sensitivity
A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste
The purpose of this study is to evaluate changes in oral health-related quality of life (OHrQoL) in participants suffering from Dentinal Hypersensitivity (DH) symptoms following the use of anti-sensitivity toothpaste for 24 weeks.
- Trial name
- NCT04964063
- Testing
- Potassium Nitrate + Sodium Fluoride
- Where
- United States
- Volunteers
- 655 people
- Sponsor
- HALEON
Dental Restoration Failure of Marginal Integrity
Influence of Surface Sealants on the Quality of Posterior Restorations With Bulk Fill Composites
Treatment clinical trial, randomized, controled, parallel, double-blinded, with three groups, that aims to evaluate if there is some advantage in applying surface sealants (Biscover, Bisco, USA or Permaseal, Ultradent, USA)…
- Trial name
- SEALBULK (NCT03924830)
- Testing
- Bulk without surface sealant, Bulk with Biscover, Bulk with Permaseal
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Hypersensitivity Dentin, Fluoride Varnishes
Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity
This randomized controlled clinical trial aims to determine whether different fluoride varnish formulations reduce dentin hypersensitivity (DH) in young adults diagnosed with DH.
- Trial name
- NCT07286344
- Testing
- Aqueous fluoride varnish, 9,500 ppm NaF, Resin/rosin-based varnish, 22,600 ppm NaF
- Where
- Chile
- Volunteers
- 92 people
- Sponsor
- University of Concepcion, Chile
Hypersensitivity Dentin
Effectiveness of the Use of Desensitizing Dentifrices Based on Nanocrystals of Hydroxyapatite / 5% Potassium Nitrate / 1450ppm Sodium Monofluorophosphate and Potassium Nitrate 5% / 1426ppm Sodium Floride in the Treatment of Dentine Hypersensitivity. Test Randomized Clinical
Background: Currently, periodontal treatment, both surgical and non-surgical, leaves sequelae in the vast majority of patients, dentine hypersensitivity (HSD) is one of the most important.
- Trial name
- NCT04156152
- Testing
- DEENSIBILIZING TOOTHPASTE BASED ON NANOCRISTALS OF HYDROXIAPATITA / 5% POTASSIC NITRATE / SODIUM MONOFluORPHOSPHATE 1450 PARTS PER MILLION, 5% POTASSIC NITRATE / SODIUM FLUORIDE 1426 PARTS PER MILLION TOOTHPASTE
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Tooth Hypersensitivity
Effect of Different Desensitizing Agents on Post-bleaching Hypersensitivity and Shade Stability
This study compared the effect of four different desensitizing agents on shade stability and dental hypersensitivity following dental bleaching procedure. The follow-up periods ranged from 24 hours to 1 year.
- Trial name
- NCT06358924
- Testing
- Potassium nitrate with fluoride, Casein phosphopeptide-amorphous calcium phosphate with fluoride, Hydroxyapatite with fluoride
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dentin Sensitivity
Effect of 1.5% Potassium Oxalate on the Control of Tooth Sensitivity and Color Change After Home Bleaching
This double-blind randomized clinical trial evaluated the effect of 1.5% potassium oxalate on pain sensitivity control and color change after home tooth whitening.
- Trial name
- NCT05028335
- Testing
- Carbamide Peroxide (PC) 22%) + Potassium Oxalate gel 1.5%
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para