Clinical trials: Teeth Sensitivity
Periodontal Diseases, Hypersensitivity Dentin
Clinical Efficacy of Vector Paro With Hydroxyapatite in the Supportive Therapy of Periodontitis
Enamel is the most calcified tissue in the body and is composed of 92-96% by organic substances in particular hydroxyapatite. Hydroxyapatite nanoparticles are similar to the morphology and structure of tooth enamel apatite…
- Conditions
- Periodontal Diseases, Hypersensitivity Dentin, Hydroxyapatite
- Trial name
- PAROXY (NCT07482280)
- Testing
- hydroxyapatite debridment, ultrasonic debridment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Dentine Hypersensitivity
Instant and Lasting Relief Effects of Strontium Chloride/Potassium Nitrate Dentifrice on Dentin Hypersensitivity
The objective of the present study was to compare the effects of a commercially available dentifrice containing 2% strontium chloride and 5% potassium nitrate in a silica base, versus a control dentifrice, containing exactly the…
- Trial name
- NCT01426360
- Testing
- control dentifrice, strontium chloride/potassium nitrate dentifrice
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Sun Yat-sen University
Dentin Hypersensitivity
Clinical Study of the Whitening Dentifrices on Tooth Color and Sensitivity
Objective:The aim of this clinical study was to evaluate tooth color alteration (ΔE) and tooth sensitivity (TS) in patients that used two commercial brand-whitening dentifrices for four weeks.
- Trial name
- NCT02483013
- Testing
- whitening dentifrices
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentine Hypersensitivity
Managing Dentine Hypersensitivity With Silver Diamine Fluoride on Older Adults
Background: Dentine hypersensitivity is a common oral complaint from older adults. It induces pain, affects oral hygiene practice, limits food choices and negatively affects the quality of life.
- Trial name
- NCT05392868
- Testing
- SDF, KNO3
- Where
- China
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Tooth Sensitivity
Effect of CPP-ACP Associated With NaF or SnF₂ on Post-Bleaching Tooth Sensitivity
This randomized, triple-blind, placebo-controlled clinical trial aims to evaluate the efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) associated with sodium fluoride (NaF) or stannous fluoride (SnF₂) in…
- Trial name
- NCT07506850
- Testing
- CPP-ACPF, CPP-ACP+SnF2
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Sensitivity
A Clinical Study to Evaluate a Stannous Fluoride Toothpaste for the Relief of Dentinal Hypersensitivity
The purpose of this study is to provide evidence of clinical efficacy of an experimental dentifrice containing stannous fluoride (SnF2) compared to regular fluoride dentifrice in the reduction of dentinal hypersensitivity (DH).
- Trial name
- NCT03310268
- Testing
- 0.454% Stannous fluoride (SnF2) and 0.072% sodium fluoride (NaF): 1450 ppm fluoride in total, 1400 ppm fluoride as sodium monofluorophosphate (SMFP), Stannous Chloride (SnCl2) and 0.15% NaF: 1450 ppm fluoride in total
- Where
- China
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity, Dentin Sensitivity
Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity
Dentin hypersensitivity (DH) can be defined as acute, short-duration pain from open dentin tubules in exposed dentin. The symptom of DH is subjective and varies from patient to patient and may present as mild discomfort or as a…
- Trial name
- NCT04591444
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentin Desensitizing Agents, Dentin Hypersensitivity, Non-carious Cervical Lesions
Clinical Efficacy of Using Bioactive Desensitizer Gel
To evaluate and compare the clinical effectiveness of a Bioactive Desensitizer Gel (which releases calcium and phosphate to form hydroxyapatite) versus a standard 5% Sodium Fluoride (NaF) Varnish in reducing cervical dentin…
- Conditions
- Dentin Desensitizing Agents, Dentin Hypersensitivity, Non-carious Cervical Lesions, Dentin Hypersensitivity
- Trial name
- NCT07323693
- Testing
- Treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Hypersensitivity
The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical Trial
The goal of this clinical trial is to compare the effect of desensitizer containing S-PRG have similar effect as sodium fluoride with functionalized tri-calcium phosphate containing desensitizer in relieving dentinal…
- Trial name
- S-PRG (NCT06276777)
- Testing
- Tooth varnish (PRG Barrier Coat from Shofu), Tooth varnish (Clinpro white varnish 3M)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eman Omar Elfarouk
Dentin Sensitivity
Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients
The main objective of this study is to evaluate the effectiveness and longevity of color and Tooth sensitivity of patients undergoing home whitening peroxide 10% carbamide ( Whiteness Perfect , FGM , Joinville , Santa Catarina …
- Trial name
- BLESMOK (NCT02017873)
- Testing
- Peroxide Carbamide 10% - Dental bleaching treatment
- Where
- 2 sites in Brazil, Chile
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Chile
Hypomineralization Molar Incisor
Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH
Introduction: Photobiomodulation (PBM) shows promising results for the complementary treatment of dentin hypersensitivity; however, few studies have evaluated this treatment specifically for teeth affected by molar incisor…
- Trial name
- NCT05370417
- Testing
- Use of fluoride toothpaste, Photobiomodulation, Simulated Laser Therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Sensitivity
Clinical Benefit of a Mouthrinse for the Treatment of Dentine Hypersensitivity
This study is to evaluate the benefit and tolerability of a Mouthrinse (IQP-OLP-101) in the treatment of dentine hypersensitivity.
- Trial name
- NCT03232255
- Testing
- Mouthrinse (IQP-OLP-101)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Molar Incisor Hypomineralization, Hypersensitivity
The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation
The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy.
- Trial name
- NCT06348849
- Testing
- Low-level laser therapy, Nanosilver fluoride
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Teeth Sensitivity, Treated Dentin Surfaces
Effect of Seashell Nanoparticles and Gluma Desensitizer on Sensitivity of Teeth
Tooth hypersensitivity is characterized by a transient short and sharp pain originating from exposed dentin in response to thermal, dehydrating, tactile, osmotic, and chemical stimuli.
- Trial name
- NCT06622018
- Testing
- Seashell Nanoparticles and Gluma Desensitizer
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Faculty of Dental Medicine for Girls
Dentine Sensitivity
Evaluation of the Effect of the Gel on Sensitive Teeth
The goal of this study is to learn if a tooth gel works to alleviate teeth hypersensitivity in adults. It will also learn about the safety of the product.
- Trial name
- NCT07596797
- Testing
- Desensitizing tooth gel
- Where
- Spain
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Lacer S.A.
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity(DH)
This single centre, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a…
- Trial name
- NCT02751450
- Testing
- Stannous Fluoride dentifice, Sodium Monofluorophosphate dentifrice
- Where
- United Kingdom
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity
Dentin hypersensitivity (DH) is a common clinical problem frequently seen in dental patients. According to Splieth et al., the prevalence of dentin hypersensitivity is 3-98% in adult population.DH is described as a short, sharp…
- Trial name
- NCT05927831
- Testing
- Grape Seed Extract, Low-level laser therapy
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Manipal University College Malaysia
Dentin Hypersensitivity
The Efficacy of a Toothpaste to Reduce Sensitivity
Hypersensitivity
- Trial name
- NCT00763269
- Testing
- Triclosan, Silicon dioxide, fluoride, Triclosan, fluoride
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentine Hypersensitivity
Efficacy of Lasers, Propolis-Based Agent, and Sham for Dentine Hypersensitivity
Dentine hypersensitivity is a common clinical problem. Although Nd:YAG lasers, diode lasers, and topical desensitizing agents are widely utilized, long-term comparative evidence regarding their clinical efficacy remains limited.
- Trial name
- NCT07647861
- Testing
- Nd:YAG Laser Application, Diode Laser Application, Herbal Propolis-Based Dentin Barrier Agent
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ondokuz Mayıs University
Allergic Rhinitis, Asthma in Children
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
The aim of the study was to evaluate if there were differences in oral findings between patients diagnosed with allergic rhinitis and/or asthma and a control group of health people.
- Conditions
- Allergic Rhinitis, Asthma in Children, Dental Caries, Periodontal Diseases
- Trial name
- NCT05576142
- Testing
- Oral examination
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pavia