Clinical trials: Teeth Sensitivity
Dentin Sensitivity
A Clinical Study Assessing the Effects of a Marketed Dentifrice on Tooth Sensitivity While Undergoing Tooth Bleaching
The aim of this study is to investigate the efficacy of a marketed dentifrice containing 5 percent (%) NovaMin (Calcium Sodium Phosphosilicate) to reduce tooth sensitivity during and post tooth bleaching compared to a marketed…
- Trial name
- NCT06608368
- Testing
- Test Dentifrice (Sensodyne Repair and Protect Original Mint), Positive Control Dentifrice (Sensodyne Fresh Mint), Reference Dentifrice (Crest Cavity Protection Regular)
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HALEON
Tooth Discoloration
Clinical Efficacy of In-office Bleaching With Different Concentrations of Hydrogen Peroxide
Objective: The study evaluated the longevity, effectiveness, sensitivity and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide.
- Trial name
- NCT06700434
- Testing
- Bleaching treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dental Sensitivity, Gingival Condition
Effects of DIammine SIlver Fluoride on Tooth Sensitivity
The purpose of the study is to confirm the clinical effectiveness and safety of topical diammine silver fluoride (DASF) as a tooth desensitizer in adulst by comparing it to the application of sterile water.
- Trial name
- NCT01063530
- Testing
- DIammine SIlver fluoride, DIstilled water
- Where
- 2 sites in Peru
- Volunteers
- 144 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Dentin Hypersensitivity
Effect of Gluma and Bioactive Glass Desensitizers in Treatment of Dentin Hypersensitivity in Cervical Non-Carious Lesions
Type of study: (A Randomized Controlled Clinical Trial) Aim :The aim of this randomized controlled clinical trial is to evaluate the effect of Gluma, Bioactive Glass and combination of both, compared to Flouride Varnish on the…
- Trial name
- NCT07063433
- Testing
- Gluma Desensitizer, Bioactive glass, Fluoride varnish
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- British University In Egypt
Tooth Sensitivity
IN-OFFICE TOOTH BLEACHING WITH 37% CARBAMIDE PEROXIDE
Objectives: This study will determine the clinical efficacy of bleaching agent 37% carbamide peroxide compared to 35% hydrogen peroxide on the change of color scores in anterior superior teeth, in-office bleaching technique after…
- Trial name
- NCT02935114
- Testing
- 37% Carbamide Peroxide, 35% hydrogen Peroxide
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Hypersensitivity Dentin, Dentin Sensitivity
Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity
The aim of this study is through a double blind randomized clinical trial, evaluate the effectiveness of different clinical protocols in the reduction of dentin hypersensitivity.
- Conditions
- Hypersensitivity Dentin, Dentin Sensitivity, Dentin Hypersensitivity, Dentine Hypersensitivity
- Trial name
- NCT03076944
- Testing
- UltraEZ, Enamelast
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of Uberlandia
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Dentin Sensitivity
A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity
The primary purpose of this study is to demonstrate the clinical efficacy of Test Toothpaste in reducing dentin hypersensitivity (DH) to an evaporative (air) stimulus, compared to a sodium fluoride reference toothpaste, after 8…
- Trial name
- NCT07802886
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- United Kingdom
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
A Comparison of Long-Term Effectiveness of Two Desensitizing Products
This randomized, controlled, clinical trial aimed to compare the 6- month clinical performance of a desensitizer that contains calcium phosphate TM with a two-step self-etch adhesive SE and placebo (distilled water).
- Trial name
- NCT03851900
- Testing
- Teethmate Desensitizer (TM), Clearfil SE Bond 2, Distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Dentin Sensitivity
A Clinical Method Development Study to Characterise The Efficacy of a Dentifrice For The Relief Of Dentin Hypersensitivity
The aim of this study is to develop the clinical methodology to characterize the efficacy profiles of an experimental 5% potassium nitrate (KNO3) and 0.454% stannous fluoride (SnF2) combination dentifrice and a marketed…
- Trial name
- NCT03361774
- Testing
- Dentifrice containing 5% w/w KNO3 and 0.454% w/w SnF2 (1100 ppm fluoride)., Dentifrice containing 0.454% w/w SnF2 (1100 ppm fluoride).
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity, Dentin Sensitivity
Cyanoacrylate and Laser and Dentin Sensitivity
This study aimed to evaluate the effectiveness of two treatments for dental hypersensitivity: cyanoacrylate (Super Bonder®) compared with use of low intensity laser treatment (LILT).
- Trial name
- Cyano-laser (NCT01111474)
- Testing
- Cyanoacrylate, Laser
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Oral Hygiene, Toothbrushing
Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash
The purpose of this open-label, randomized controlled clinical trial, is to provide preliminary clinical data (efficacy on plaque and gingival sensitivity, and safety and tolerability of two types of toothpaste, a mouthwash, and…
- Conditions
- Oral Hygiene, Toothbrushing, Dental Plaque
- Trial name
- NCT05999175
- Testing
- the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days., the mint toothpaste and mouthwash are used with the scalar toothbrush 33 medium with antibacterial " Spazzolino tau-marin®" 3 times a day after the main meals for 28 days., subjects of this group will use their routine oral hygiene products.
- Where
- 2 sites in Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Biokosmes Srl
Tooth Sensitivity
Effect of Tri Calcium Phosphate on Efficacy and Sensitivity With Vital Tooth Whitening Using 20% Carbamide Peroxide
Teeth sensitivity is the most popular symptom when using At-Home tooth whitening. Tri calcium phosphate containing pastes may affect the efficacy and postoperative sensitivity associated with At-Home vital tooth whitening using…
- Trial name
- NCT03026725
- Testing
- Tri-calcium Phosphate
- Where
- Syria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dentin Hypersensitivity
Silver and Fluoride Salivary Levels After the Application of Silver Fluoride
The aim of the study is to measure salivary fluoride and silver levels up to 7 days post-treatment. The participants will be 6 healthy adults.
- Trial name
- NCT01860391
- Testing
- Diammine Silver Fluoride
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Dentin Hypersensitivity
Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice
The aim of this clinical study is to demonstrate the superior antihypersensitivity efficacy of a novel stannous fluoride (SnF2) and potassium nitrate (KNO3) dentifrice (Investigational Product), compared to SnF2 only, KNO3 only…
- Trial name
- NCT07215767
- Testing
- Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice
- Where
- 3 sites in United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- HALEON
Tooth Bleaching, Pain
Effects of an Experimental Propolis Gel on Tooth Sensitivity Control and Post-bleaching Color Change: a Randomized Clinical Trial
This randomized, parallel, double-blind, placebo-controlled clinical study aims to investigate the effects of an experimental 0.5% propolis gel on controlling tooth sensitivity and discoloration after in-office dental bleaching.
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT07569276
- Testing
- Propolis gel, KF2- Potassium nitrate
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal do Para
Molar Incisor Hypomineralization
Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients
The goal of this clinical trial is to examine the clinical success of different pre-treatments in resin infiltration therapy applied to the incisors of pediatric patients with Molar Incisor Hypomineralization (MIH) and to…
- Trial name
- NCT07469124
- Testing
- Resin Infiltration, Microabrasion Followed by Resin Infiltration, Air Abrasion Followed by Resin Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Inonu University
Enamel Erosion
Meta-analysis of Stannous Fluoride and the Effects on Enamel Erosion
The aim of this 5 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices to assess enamel erosion protection in-situ using surface profilometry.
- Trial name
- NCT04006470
- Testing
- Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Patient Satisfaction, Bleaching Efficacy
Patient Satisfaction With At-home Dental Bleaching Using Orthodontic Retainers With Different Margin Designs
This randomized single-blind, split-mouth clinical trial evaluated patient satisfaction with at-home dental bleaching using orthodontic retainers with different margin designs, as well as bleaching efficacy, tooth sensitivity…
- Conditions
- Patient Satisfaction, Bleaching Efficacy, Tooth Sensitivity, Gingival Irritation
- Trial name
- NCT07208708
- Testing
- Scalloped margin retainer, Straight orthodontic retainer
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Rey Juan Carlos
Tooth Sensitivity
The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.
The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent…
- Trial name
- NCT07173296
- Testing
- Opalescence XTra Boost 40% HP, Pola Office Plus 37.5% HP
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital