Clinical trials: Teeth Sensitivity
Toothache, Tooth Bleaching
Naproxen on Tooth Sensitivity Caused by In-office Bleaching
This study aims to evaluate the effects of prior use of non-steroidal anti-inflammatory Naproxen on risk and level of tooth sensitivity caused by in-office bleaching procedures.
- Trial name
- NCT02463552
- Testing
- Naproxen
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dentin Hypersensitivity
Desensitizers in Reducing Post Tooth Preparation Sensitivity for a Fixed Dental Prosthesis
The main purpose of the present study was to evaluate and compare the effectiveness of three kinds of commercially available desensitizing agents: Gluma, Sheildforce plus, and Telio CS desensitizers in reducing the pre- and…
- Trial name
- NCT04512625
- Testing
- Desensitizers
- Where
- Saudi Arabia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Sensitivity, Tooth
Postoperative Sensitivity Following Placement with Different Restorative Materials in Vital Posterior Teeth
There is a lack of long-term clinical studies comparing different restorative materials; most of the available studies have only looked at class I cavities or examined post-operative sensitivity in non-caries cervical lesions.
- Trial name
- GCP (NCT05882760)
- Testing
- Tetric N Bond Universal®, Self Etch Tetric N Bond Universal®, GC Fuji IX, GC, Japan®
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Sensitivity, Tooth
To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpaste in the Reduction of Dentinal Hypersensitivity.
The objective of this clinical investigation is to assess the efficacy of a toothpaste containing 8% arginine (Colgate-Palmolive Company, New York, NY, USA) as compared to a commercially available non-desensitizing toothpaste…
- Trial name
- NCT07149376
- Testing
- TOMs of Maine Sensitive SLS Free Xtra Fresh, Colgate Cavity protection toothpaste
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Hypersensitivity
Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticles in the management of…
- Trial name
- NCT06557980
- Testing
- toothpaste
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical dentin hypersensitivity (DH) efficacy of a 5 percent (%) calcium sodium phosphosilicate (CSPS) toothpaste.
- Trial name
- NCT06378008
- Testing
- CSPS toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- Canada
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- HALEON
Molar-Incisor Hypomineralization (MIH)
Nano Silver Fluoride and Photobiomodulation Therapy for Hypersensitivity and Pain in MIH-Affected Molars
Molar-incisor hypomineralization (MIH) is a developmental condition affecting primarily the first permanent molars and may be associated with post-eruptive enamel breakdown, hypersensitivity, and difficulties in achieving…
- Trial name
- NCT07826130
- Testing
- Nano Silver Fluoride, Photobiomodulation Therapy, Pre-appointment analgesics
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Composite Resins, Teeth Sensitivity
Clinical Evaluation of Short Fiber-Reinforced Composite Restorations With and Without Preheating Approach
To clinically evaluate the performance of preheated versus non-preheated short fiber-reinforced composite (SFRC) restorations in Class I posterior cavities over a 12-month period
- Conditions
- Composite Resins, Teeth Sensitivity, Restoration Design, Composite Restoration
- Trial name
- NCT07496047
- Testing
- Preheated everX Posterior composite, Non-preheated everX Posterior composite
- Where
- 2 sites in Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dental Restoration Failure of Marginal Integrity
Clinical Evaluation of Bulk Fill Composite Restorations Associated to Universal Adhesive System
Treatment clinical trial, randomized, controled, parallel, double-blinded, with four groups, that aims to evaluate the best application strategy when using a Universal Adhesive system, Single Bond Universal (3M ESPE, USA), in…
- Trial name
- FBFSBU (NCT03343184)
- Testing
- SEE Strategy and Incremental Restoration, SEE Strategy and Bulk Fill Restoration, SET Strategy and Incremental Restoration
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dentine Hypersensitivity
Efficacy of Novel Titania Nanoparticles Enriched Mouth Wash in Treating Dentine Hypersensitivity
Randomized Clinical trial to compare the reduction in dentin hypersensitivity after incorporating biogenically fabricated titania nanoparticles enriched Mouth Wash and Conventional Mouth Wash.Participants ranging between 20-50…
- Trial name
- NCT06790953
- Testing
- Group- A Conventional Sensed Mouth Wash, Group-B Novel Titania nanoparticles enriched Mouth Wash
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Hypersensitivity, Hypersensitivity, Immediate
Assessment of Er:YAG Laser for the Control of Hypersensitivity During Tooth Whitening With Hydrogen Peroxide
Introduction: Tooth whitening is an aesthetic procedure with rapid results that improves the self-esteem and self-image of patients. However, one of the side effects is dentinal hypersensitivity.
- Conditions
- Hypersensitivity, Hypersensitivity, Immediate, Hypersensitivity Response
- Trial name
- NCT06538129
- Testing
- Hypersensitivity prevention protocol with Er:YAG laser, Hypersensitivity prevention protocol with neutral sodium fluoride gel
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Sensitivity, Molar Incisor Hypomineralization
MIH and Hypersensitivity in Children
The aim of this study was to evaluate the efficacy of the association of casein phosphopeptide plus amorphous calcium phosphate (CPP-ACPF) mousse and photo-bio-modulation therapy (PMBT) (diode laser, RAFFAELLO 980 BIO - Dental…
- Trial name
- NCT05705037
- Testing
- CPP-ACPF, PBMT, CPP-ACPF+PBMT
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Tooth Sensitivity, Tooth Bleaching
Photobiomodulation Before or After Tooth Whitening
The objective is to evaluate the effect of photobiomodulation (PBM) applied before or after in-office tooth whitening in reducing tooth sensitivity (TS) and color change.
- Conditions
- Tooth Sensitivity, Tooth Bleaching, Laser Therapy
- Trial name
- NCT06518629
- Testing
- Photobiomodulation with low power laser
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Color; Change Teeth, Posteruptive
Clinical Comparison of LED- and Diode Laser-activated Bleaching
To clinically compare the effects of LED- or Diode laser-activated bleaching on colour change, tooth-sensitivity, gingival-irritation and temperature variation over 9-months.
- Trial name
- NCT04537754
- Testing
- bleaching device
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dentin Hypersensitivity
A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity
The objective of this study is to evaluate the efficacy (changes in dentinal hypersensitivity) and safety (oral soft tissue evaluation) after use of one of four dentifrices in subjects with pre-existing hypersensitivity over an…
- Trial name
- NCT03965039
- Testing
- Dipotassium oxalate toothpaste, Stannous fluoride toothpaste, Potassium nitrate toothpaste
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dental Caries, Dentin Sensitivity
Comparative Evaluation of the Post Operative Sensitivity of Cention-N(Commercially Available Restorative Material) Using Conventional and Polymer Bur- In-vivo Study
Cention-N(commercially available restorative material) is a cost effective restoration for posterior restorations. Post-operative sensitivity is of great concern as far as any type of restorative material is concerned.
- Trial name
- NCT05185206
- Testing
- Class 1 cavity preparation using conventional steel bur and restoration with Cention-n(commercially available restorative material)., Class 1 cavity preparation using polymer bur and restoration with Cention-n(commercially available restorative material).
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Pain, Dentin Sensitivity
Effect of an Experimental Gel Containing Copaiba Oil-resin in the Control of Dentin Hypersensitivity
This randomized, single-blind, placebo-controlled clinical trial aims to clinically evaluate the effect of an experimental gel containing copaiba oleo-resin in the control of dentin hypersensitivity (DH) in non-carious cervical…
- Conditions
- Pain, Dentin Sensitivity, Dentin Desensitizing Agents
- Trial name
- NCT06872749
- Testing
- KF2 (Potassium nitrate gel), experimental Copaiba gel
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentine Hypersensitivity
Dentine Hypersensitivity Using Dentine Adhesive With Strontium-doped Bioactive Glass-Ceramic
The goal of this clinical trial is to determine whether strontium-doped bioactive glass-ceramic (SBGC)-filled dentine adhesive is effective in relieving dentine hypersensitivity.
- Trial name
- NCT07628712
- Testing
- Strontium-doped bioactive glass-ceramic-filled dentine adhesive, Universal dentine adhesive
- Where
- 2 sites in Hong Kong
- Volunteers
- 142 people
- Sponsor
- The University of Hong Kong
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
This single centre, dual site, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use
- Trial name
- NCT02612064
- Testing
- Stannous Fluoride dentifice, Sodium Monofluorophosphate dentifrice
- Where
- 2 sites in United Kingdom
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Molar Incisor Hypomineralization
HYPERSENSITIVITY IN MOLAR INCISOR HYPOMINERALISATION USING LOW LEVEL LASER IN CHILDREN
Molar Incisor Hypomineralisation (MIH) is a qualitative defect of enamel that shows asymmetrically involvement of one to four on first permanent molars (FPM) with or without incisor teeth involvement.
- Trial name
- NCT06154733
- Testing
- Photobiomodulation usinf low level laser therapy, Resin-based sealant, Glass ionomer sealant
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Alexandria University