Clinical trials: Teeth With Root Canal Treatment
Dental Pulp Necroses, Apical Periodontitis
Effects of Intracanal Cryotherapy on Endodontic Postoperative Pain
The goal of this clinical trial is to evaluate the effect of cold saline (2.5 degrees Celsius) irrigation on postoperative pain in patients who require root canal treatment in molar teeth because of dead dental pulp and infection…
- Conditions
- Dental Pulp Necroses, Apical Periodontitis, Post Operative Pain
- Trial name
- NCT05611736
- Testing
- cold saline, saline
- Where
- Saudi Arabia
- Volunteers
- 302 people
- Sponsor
- Qassim University
Asymptomatic Apical Periodontitis, Root Canal Infection
Effect of EDDY Sonic Irrigation on Root Canal Microbiota and Pain in Asymptomatic Apical Periodontitis
This randomized controlled clinical trial aimed to evaluate the effect of sonic activation using the EDDY device on root canal microbiota and postoperative pain in teeth with asymptomatic apical periodontitis.
- Conditions
- Asymptomatic Apical Periodontitis, Root Canal Infection, Periapical Diseases, Dental Pain
- Trial name
- NCT07120126
- Testing
- EDDY Sonic Activation, Conventional Syringe Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Abdulkadir Tiftik,DDS
Asymptomatic Molar Teeth With Periapical Lesions
Postoperative Pain After Root Canal Preparation Using Different Engine-driven Systems
A hundred twenty patients who had an asymptomatic mandibular molar teeth with periapical lesion were included. For each patient, teeth were prepared with Reciproc Blue or Protaper Universal instruments.
- Trial name
- NCT04454814
- Testing
- Protaper Universal instruments, Reciproc Blue instruments
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ege University
Postoperative Pain
Can the Different Instruments Used ın Root Canal Treatment Have an Effect on Postoperative Pain?
Root canal treatment is a treatment method in which the pulp is irreversibly infected due to caries or trauma or when the pulp loses its vitality.
- Trial name
- NCT05927025
- Testing
- Hand K-files
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Immature Permanent Teeth With Open Apex, Pulp Necrosis
Regenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty Acids
This clinical study will be conducted to evaluate the effect of using intracanal Omega-3 Fatty acids during revascularization of necrotic immature teeth compared to the traditional induced bleeding technique.
- Trial name
- Regeneration (NCT07371416)
- Testing
- Omega -3 fatty acids, Calcium Hydroxide (Ca(OH)2)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endodontic Disease
Treatment Outcome of Ortho MTA (BioMTA®) Cement vs AH Plus® Bioceramic Sealer (Dentsply).
The use of bioceramics materials as root canal fillings in endodontics is gaining traction due to their excellent biocompatibility, antibacterial and sealing abilities.
- Trial name
- NCT05984940
- Testing
- Ortho MTA cement, GP and AH Plus sealer
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- National University Hospital, Singapore
Apical Periodontitis
Outcome of Regenerative Endodontic Procedure and Root Canal Treatment for the Management of Apical Periodontitis
Background Root canal therapy is the primary treatment of choice for necrotic mature teeth with periapical lesions (PRLs), which does not restore the tooth's vitality.
- Trial name
- NCT06179433
- Testing
- Root canal treatment, Regenerative endodontic procedure
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Teeth With Root Canal Treatment
Post-endodontic Access Cavity Cleaning Techniques
Aim This study aims to evaluate the effectiveness of different post-endodontic access cavity cleaning techniques (PACCTs) in removing residual epoxy resin-based root canal sealer from the pulp chamber floor following root canal…
- Trial name
- NCT06937424
- Testing
- Dry cotton pellet group, Ethanol-saturated cotton pellet 7 seconds group, Ethanol-saturated cotton pellet visibly clean group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Dental Pulp Necrosis
Root Canal Treatment in Primary Molars With Necrotic Pulp Using Two Different Pulp Therapies
This is a controlled, randomized, double-blind clinical study (researcher and research participant does not know which group they belong to), with the objective of evaluating clinical and radiographic performances of primary…
- Trial name
- NCT03650036
- Testing
- Pulp Therapy CTZ Paste, Pulp Therapy ZOE Paste
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- Federal University of Piaui
Irreversible Pulpitis, Symptomatic Irreversible Pulpitis
To COMPARE the EFFECT of TWO INSTRUMENTATION TECHNIQUES on the INCIDENCE of POST-ENDODONTIC PAIN in PATIENTS UNDERGOING ROOT CANAL TREATMENT in TEETH with IRREVERSIBLE PULPITIS
The aim of this study is to compare the post endodontic pain in patients presenting with irreversible pulpitis and undergoing root canal treatment with two techniques.
- Conditions
- Irreversible Pulpitis, Symptomatic Irreversible Pulpitis, Asymptomatic Irreversible Pulpitis
- Trial name
- NCT06842251
- Testing
- Rotary Crown Down Technique, Manual Step Back Technique
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Urooj Fatima
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator
Patients with painful molars will be randomly assigned to 2 different groups: GentleWave and EndoActivator. The root canals will be completed using identical protocols except in the mode of delivery and activation of irrigation…
- Trial name
- NCT04552132
- Testing
- Multisonic vs Sonic activation of irrigants
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Irreversible Pulpitis (Toothache), Dental Caries (Diagnosis)
Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis
The goal of This current study compare the clinical \& radiographic success rate between two different modalities conventional RCT and VPT using Bio-C-Repair as a pulp capping material to treat young patients with mature first…
- Trial name
- NCT07046533
- Testing
- (pulpotomy), root canal treatment
- Volunteers
- 60 people
- Sponsor
- Lamiaa Saeed Ahmed Elshiekh
Necrotic Pulp, Apical Periodontitis
Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical Periodontitis
The aim of this prospective, randomized, controlled double-blind study is to evaluate the effectiveness of biodentine compared with MTA used as pulp space barrier on discoloration of teeth after regenerative based non-obturation…
- Trial name
- NCT04018456
- Testing
- Biodentine, White MTA
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Post-treatment Pain Following Root Canal Therapy
Evaluation of the Effect of Saffron (Crocus Sativus) on Pain Control After Root Canal Therapy in Teeth With Vital Pulps
The purpose of this study is to determine whether saffron is effective in the pain control after root canal therapy in vital teeth.
- Trial name
- NCT01590485
- Testing
- starch, saffron
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Apical Periodontitis, Periapical Lesion
Evaluation of Different Root Canal Obturation Techniques
The aim of this clinical study is to evaluate the effect of root canal filling, which is the last stage of root canal treatment (RCT), on the post-operative pain level on single rooted permanent teeth with wide lesions with…
- Trial name
- NCT07106307
- Testing
- Bioceramic Sealer, Warm Vertical Compaction, Epoxy Resin-Based Sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Medipol University
Postoperative Pain After Endodontic Treatment, Direct Pulp Capping
Diagnostic Validity of a Quantitative Pulp Pain Scoring System and Its Association With Postoperative Clinical Outcomes
Pulpal diseases are among the most common reasons for endodontic treatment in dental practice. The dental pulp plays a critical role in maintaining tooth vitality, and its pathological changes directly affect pain perception and…
- Conditions
- Postoperative Pain After Endodontic Treatment, Direct Pulp Capping, Vital Pulp Therapy
- Trial name
- NCT07349511
- Testing
- Root canal treatment procedure based on the total score obtained from the Youden symptom scoring system, Vital pulp therapy procedure based on the total score obtained from the Youden symptom scoring system
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people
- Sponsor
- Recep Tayyip Erdogan University
Periapical Diseases
Evaluation of Post Operative Pain After Using Intracranial Cryotherapy During Single Visit RCT
A total of 60 patients presenting with single-rooted teeth exhibiting symptomatic apical periodontitis were subjected to a randomized allocation into two groups of 30 each.
- Trial name
- NCT07598188
- Testing
- Saline 0.9% (1.5-2.5°C)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Apical Periodontitis
N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis
A randomized controlled trial comparing the postoperative pain intensity, periapical biomarkers level, and periapical healing in patients with necrotic mature teeth and apical periodontitis treated with N-acetylcysteine (NAC), as…
- Trial name
- NAC (NCT07262554)
- Testing
- Calcium hydroxide (Ca(OH)₂), N-Acetylcysteine (NAC)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University