Clinical trials: Telomere Disease
Telomere Shortening, Bone Marrow Failure
Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure
This is a Phase I/II, open label, single center study to assess the safety and tolerability of EXG34217 in bone marrow failure patients with telomere biology disorders.
- Trial name
- NCT04211714
- Testing
- EXG34217
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Elixirgen Therapeutics, Inc.
Aging, Stress
Fitness, Cellular Aging, and Caregiver Stress Study
The purpose of this study is to determine whether an aerobic training intervention will alter markers of immune cell aging, improve exercise capacity and blood pressure and decrease psychological distress over 24 weeks in 32…
- Conditions
- Aging, Stress, Disease Risk
- Trial name
- FAST (NCT01993082)
- Testing
- Aerobic Training Intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stress, Breast Cancer
Stress Management and Biological Age in Breast Cancer Patients.RCT
Intense stress has harmful effects on the body, contributing to various disorders. Breast cancer patients experience a build-up of stress due to their diagnosis and treatments.
- Conditions
- Stress, Breast Cancer, Telomere Length, Mean Leukocyte
- Trial name
- NCT05984914
- Testing
- PSAI, One day seminar
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Maria Charalampopoulou
Male Infertility
Relationship Between Sperm Head Vacuoles and Sperm DNA Alterations in Infertile Men
In men presenting sperm alterations, the selection of genetically undamaged spermatozoa need to be improved in order to increase the success of assisted reproduction treatments.
- Trial name
- VATES (NCT02006446)
- Testing
- Sperm Samples
- Where
- 2 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen