Clinical trials: Temperature, active
Still's Disease, Adult-Onset, Systemic Inflammation
Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions
Background: Inflammatory conditions can cause symptoms like fevers, arthritis, and rash. Systemic juvenile idiopathic arthritis (sJIA) is one of these conditions. So is adult-onset Still s disease (AOSD).
- Conditions
- Still's Disease, Adult-Onset, Systemic Inflammation, Arthritis, Autoinflammatory Syndrome
- Trial name
- NCT03510442
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Compassion
Electrocoagulation vs. Cold Knife Cutting in Joint Arthroplasty (Electrocoagulation vs Scalpel)
Comparison of clinical outcomes of electrocoagulation and non-electrocoagulation techniques in total hip and knee arthroplasty surgery
- Trial name
- evs (NCT06251869)
- Testing
- total hip arthroplasty with electrocoagulation, total hip arthroplasty without electrocoagulation, total knee arthroplasty with electrocoagulation
- Where
- Romania
- Volunteers
- 700 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Fever, Cancer
Remote Temperature Monitoring of Patients At Risk for Developing Fever
The purpose of this program is to evaluate remote temperature monitoring in cancer patients at risk of fever and infection due to chemotherapy treatment.
- Conditions
- Fever, Cancer, Remote Patient Monitoring
- Trial name
- NCT06752512
- Testing
- Remote Patient Monitoring
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- AION Biosystems
Tourette's Disorder, Insomnia
Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder
The primary aim of the present research project is to investigate the preliminary effects of four weeks of forehead temperature-regulating therapy on insomnia in adults with Tourette's disorder and co-occurring insomnia disorder.
- Trial name
- NCT05499741
- Testing
- Forehead Temperature-Regulating Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Los Angeles
Hamstring Injuries, Hamstring Muscle Repair
Thermal Therapies in the Treatment of Muscle Injuries
Muscle strain injuries represent one of the most prevalent injuries in athletes. Despite this high injury prevalence, there is no evidence to support some of the currently used therapeutic strategies.
- Conditions
- Hamstring Injuries, Hamstring Muscle Repair, Hamstring Muscles, Hamstring Rupture
- Trial name
- NCT07045129
- Testing
- Cold water immersion, Hot water immersion, Physiotherapy only
- Where
- Qatar
- Volunteers
- 135 people
- Sponsor
- Aspetar
Septic Shock
Fever Control Using External Cooling in Mechanically Ventilated Patients With Septic Shock
The best strategy for managing fever in patients with septic shock remains unknown. In a pilot study, the investigators showed that fever control at normothermia allowed a better control of shock and evolution of organ failures.
- Trial name
- NCT04494074
- Testing
- External Cooling
- Where
- 33 sites in France
- Volunteers
- 820 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Cardiac Arrest (CA), Proteomics
Proteomic Analysis of Serum Samples After Cardiac Arrest: a TTM-trial Substudy
Cardiac arrest remains a large contributor to morbidity and mortality. Animal studies suggest an improvement in mortality and neurological function with hypothermia after cardiac arrest, a finding that could not be verified in…
- Trial name
- NCT07017374
- Testing
- Proteomic analysis, targeted temperature management
- Where
- Sweden
- Volunteers
- 682 people
- Sponsor
- Region Skane
Epidural Related Maternal Fever, Analgesia, Epidural
The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever
This study investigates how the temperature of local anesthetics affects maternal fever related to epidural analgesia during childbirth.
- Conditions
- Epidural Related Maternal Fever, Analgesia, Epidural, Fever, Intrapartum Fever
- Trial name
- NCT06682416
- Testing
- In the context of epidural analgesia, the temperature of the local anesthetic solution is elevated to 37°C utilizing a blood transfusion and infusion warmer.
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- The First Affiliated Hospital of Soochow University
HER2-negative Breast Cancer
Neoadjuvant Concomitant Modulated Electro-hyperthermia in HER2-negative Breast Cancer
The aim of this study is to investigate whether the application of concomitant modulated electro-hyperthermia in a neoadjuvant chemotherapeutic setting is beneficial for patients with HER2-negative, stage II-III breast cancer.
- Trial name
- NeoHTerMa (NCT05889390)
- Testing
- Oncotherm EHY-2030, Paclitaxel, Carboplatin
- Where
- Hungary
- Volunteers
- 71 people
- Sponsor
- Semmelweis University
Refractive Errors
Effect of Colour Temperature of Reading Lamp on Refractive Error Development
This is a 12-month longitudinal randomized controlled trial aiming to evaluate the effect of colour temperature of reading lamp on refractive error development.
- Trial name
- NCT05733182
- Testing
- 3000K Reading lamp, 4500K Reading lamp, 6500K Reading lamp
- Where
- Hong Kong
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Systemic Juvenile Idiopathic Arthritis
A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)
The reason for this study is to see if the study drug baricitinib is safe and effective in participants from 1 year to less than 18 years old with systemic juvenile idiopathic arthritis (sJIA).
- Trial name
- NCT04088396
- Testing
- Baricitinib, Tocilizumab
- Where
- 55 sites in Argentina, Belgium and 12 more
- Volunteers
- 58 people
- Sponsor
- Eli Lilly and Company
Tonsil Disease, Tonsillitis
Intracapsular Tonsillectomy in Adults
Comparing the classical extracapsular tonsillectomy (TE) performed with electrosurgery to intracapsular approaches (SIPT) by coblation or microdebrider. The patient group is adults with recurrent or chronic tonsillitis
- Conditions
- Tonsil Disease, Tonsillitis, Tonsillitis Acute, Tonsillitis Chronic
- Trial name
- NCT03654742
- Testing
- tonsillectomy
- Where
- Finland
- Volunteers
- 167 people
- Sponsor
- Turku University Hospital
Acute Respiratory Infections, Febrile Illnesses
The Fever Clinic Acute Respiratory Cohort
This prospective cohort study aims to characterize the natural progression and outcomes of acute respiratory infections among patients presenting to fever clinics.
- Conditions
- Acute Respiratory Infections, Febrile Illnesses, Community-acquired Pneumonia, Viral Respiratory Tract Infections
- Trial name
- FACTS (NCT07278700)
- Testing
- No intervention involved
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Fudan University
Acute Ischemic Stroke
An Application Provides Temperature-related Health Risk Warnings and Protective Recommendations on Stroke
This study applied an application to provide early warnings and advice for stroke patients and explored the impact of this intervention on reducing the risk of stroke recurrence
- Trial name
- NCT07097428
- Testing
- Temperature health risk early warning
- Volunteers
- 5,092 people
- Sponsor
- Xuanwu Hospital, Beijing
Cutaneous Metastatic Melanoma
Intratumoral Targeted Hyperthermia Therapy (THT) for Cutaneous Metastatic Melanoma
This device phase I/II, first in human, early feasibility study (EFS), open-label, single-arm trial aims to evaluate the safety, tolerability, and preliminary efficacy of Gold Nanorod (GNR)-enabled sub-ablative targeted…
- Trial name
- NCT06870994
- Testing
- Targeted Hyperthermia Therapy
- Volunteers
- 10 people
- Sponsor
- Sona Nanotech Inc
Preterm Infant, Body Temperature
Air vs. Cutaneous Control Mode for Preterm Infants ≤ 32 WG in Incubators: Impact on Body Growth and Morbidity
Previous studies have shown that mortality and morbidity in preterm neonates are correlated with the fall in body temperature on admission. Hypothermia can be decreased by reducing body heat losses to the environment.
- Trial name
- ThermoKPreterm (NCT03919188)
- Testing
- air temperature control (ATC), skin servocontrol (SSC)
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Stroke, Acute Ischemic
Role of Hypothermia in Endovascular Stroke Thrombectomy
Reducing or suspending the increase of the infarcted core, i.e., "freezing" the ischemic penumbra, may help improve the efficacy of mechanical thrombectomy.
- Trial name
- COOLING (NCT06109376)
- Testing
- hypothermia, thrombectomy
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Xinqiao Hospital of Chongqing
Gynaecologic Cancer
More Representative Vaginal Temperature Measurements With a Hyperthermia Pelotte During Hyperthermia Treatments for Gynaecological Cancer.
The goal of this comparative, cross over single centre study is to to determine whether the average measured vaginal temperature during hyperthermia treatment is (clinically) significant different with the use of a pelotte than…
- Trial name
- ORIENTATE (NCT07235540)
- Testing
- Pelotte
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Dr. G.H. (Henrike) Westerveld
Hypothermia, Accidental, Hypothermia; Anesthesia
Constructing a Risk Prediction Model for Intraoperative Hypothermia in Children Under General Anesthesia
Intraoperative hypothermia refers to a core body temperature below 36.0°C during surgery, which is common in surgical patients. Due to the fact that children's body temperature regulation function is not yet fully developed, they…
- Trial name
- NCT06892795
- Where
- China
- Volunteers
- 562 people
- Sponsor
- Harbin Medical University
Achalasia, Achalasia Cardia
Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophageal Myotomy
Peroral endoscopic esophagel myotomy (POEM) is a third space endoscopy technique that depends on creating a submucosal tunnel to expose the esophageal muscle and eventually perform an esophageal myotomy.
- Trial name
- NCT06189859
- Testing
- endoscopic submucosal dissection using SPRAY COAG mode, endoscopic submucosal dissection using Precisect mode
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University