Clinical trials: Temperature Change, Body
Fever After Vaccination, Fever
Fever After Simultaneous Versus Sequential Vaccination in Young Children
A prospective, randomized open-label clinical trial that will be conducted during the 2017-2018 influenza season. During the 2017-2018 season, approximately 280 children will be enrolled at Duke University Medical Center and…
- Conditions
- Fever After Vaccination, Fever, Febrile Seizure
- Trial name
- NCT03165981
- Testing
- PCV13, DTaP, IIV
- Where
- 3 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Duke University
Epithelial Ovarian Cancer, Fallopian Tube Carcinoma
Hyperthermic Intraoperative Intraperitoneal Chemotherapy of Recurrent Ovarian Cancer - A Feasibility Study
Most studies performing hyperthermic intraoperative intraperitoneal chemotherapy dose the cytotoxic drugs according to the body surface (like 50 mg/m² cisplatin) in analogy to systemic, intravenous chemotherapy (usually using the…
- Trial name
- NCT00968799
- Testing
- Hyperthermic intraoperative intraperitoneal chemotherapy, Cytoreduction, Cisplatin
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- Cantonal Hospital of St. Gallen
Kangaroo Mother Care, Preterm Infant
Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa
We will conduct an individually randomised, controlled, superiority trial with two parallel groups; an intervention arm allocated to receive KMC and a control arm receiving 'standard' care.
- Conditions
- Kangaroo Mother Care, Preterm Infant, Death; Neonatal, Hypothermia, Newborn
- Trial name
- OMWaNA (NCT02811432)
- Testing
- Kangaroo mother care, Standard care
- Where
- 4 sites in Uganda
- Volunteers
- 2,221 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Hypothermia; Anesthesia, Hypothermia, Newborn
Perioperative Warming Measures in Cesarean Delivery
The purpose of this study is to evaluate the best method for keeping patients warm during cesarean deliveries and the effect of temperature change on the patient and baby
- Conditions
- Hypothermia; Anesthesia, Hypothermia, Newborn, Hypothermia, Sequela
- Trial name
- NCT05015582
- Testing
- Pre op upper body forced air warming (32˚C), Pre op lower body forced air warming (32˚C), Pre op fluids (45˚C)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center, Houston
Temperature Change, Body
The Effect of Convective Pre-warming on Intra-operative Thermoregulatory Capabilities
This prospective randomized clinical trial will assess the effect of pre-operative convective warming on intra-operative thermoregulation in patients undergoing gastrointestinal or genitourinary surgical procedures with the Tiger…
- Trial name
- NCT03876808
- Testing
- Bair Hugger™ Temperature Management Unit Model 750, 3M™ Bair Paws™ Flex Gown
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Cough, Sore Throat
A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza
A Phase 3, multicenter, randomized, double-blind, controlled study to evaluate the efficacy and safety of peramivir administered intravenously in addition to standard of care compared to standard of care alone in adults and…
- Conditions
- Cough, Sore Throat, Nasal Congestion, Headache
- Trial name
- NCT00958776
- Testing
- Peramivir+SOC
- Where
- 196 sites in United States, Argentina and 21 more
- Volunteers
- 405 people
- Sponsor
- BioCryst Pharmaceuticals
Preterm Infant, Hypothermia, Newborn
Early Kangaroo Mother Care in Gambian Hospitalised Unstable Neonates
The mortality effect of kangaroo mother care in stable newborns <2000g is well established but mortality effect in unstable newborns is not conclusively known.
- Conditions
- Preterm Infant, Hypothermia, Newborn, Death, Kangaroo Mother Care
- Trial name
- eKMC (NCT03555981)
- Testing
- Early Kangaroo Mother Care, Standard care
- Where
- The Gambia
- Volunteers
- 279 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Surgery, Temperature Change, Body
Warming Blanket Comparison Study
The purpose of the study is to compare the effectiveness of resistive blanket warming to forced air warming in maintaining body temperature in participants undergoing renal transplantation.
- Trial name
- NCT04776954
- Testing
- Forced Air Warming System, Resistive Blanket Warming System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Pain, Fever
Medication Education for Dosing Safety
Acetaminophen and ibuprofen are two of the most commonly used medication products among children <12 years old, and these medications are frequently prescribed for patients leaving the emergency department (ED), but previous…
- Trial name
- MEDS (NCT03223246)
- Testing
- Additional teaching
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder, Depression
HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2
This randomized two-arm intervention trial administers 8 weekly cognitive behavioral therapy (CBT) sessions and 4 bi-weekly active whole-body hyperthermia (active WBH) sessions or 4 bi-weekly sham WBH sessions to adults aged 18…
- Trial name
- HEATBED2 (NCT05708976)
- Testing
- Cognitive Behavioral Therapy (CBT), Active Whole-Body Hyperthermia (Active WBH)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Hypothermia
Intraoperative Warming Comparison of Devices
Hypothermia is a common and serious complication during anesthesia and surgery. Anesthetic-induced hypothermia results from the inhibition of thermoregulatory control and exposure to cold operating room environment.
- Trial name
- NCT00650260
- Testing
- Dynatherm Medical vitalHEAT Temperature Management System vH2, Bair Hugger™ (Arizant Healthcare, Eden Prairie, MN)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Fever After Vaccination, Fever
Safety of Simultaneous mRNA COVID-19 Vaccine With Other Childhood Vaccines in Young Children
This is a prospective, randomized, open-label clinical trial to evaluate the safety of COVID-19 vaccination and other routine childhood vaccines given simultaneously at Visit 1, as compared to sequential vaccination of COVID-19…
- Conditions
- Fever After Vaccination, Fever, Seizures Fever
- Trial name
- NCT06038617
- Testing
- mRNA COVID-19 Vaccine, Routine Childhood Vaccinations
- Where
- 5 sites in United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Duke University
Osteoarthritis, Knee, Menopause
Efficacy Study of Shortwave Diathermy for the Treatment of Patients With Knee Osteoarthritis
The purpose of this study is to determine whether shortwave diathermy is effective in reducing knee pain and increasing function of the patients with knee osteoarthritis.
- Trial name
- NCT00199914
- Testing
- Shortwave diathermy
- Where
- Thailand
- Volunteers
- 113 people
- Sponsor
- Mahidol University
Fever
Hospital Admissions in Children Aged 3 Months to 5 Years Presenting With Fever to the Emergency Department
This study primarily aims to describe factors associated with hospitalisation of children aged 3 months to 5 years presenting with fever to an urban paediatric A\&E departments by describing and analysing characteristics both of…
- Trial name
- NCT01196793
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Asphyxia Neonatorum, Hypoxia
TOBY (TOtal Body hYpothermia): a Study of Treatment for Perinatal Asphyxia
Hypothesis: Prolonged whole body cooling in term infants with perinatal asphyxial encephalopathy reduces death and severe neurodevelopmental disability.
- Conditions
- Asphyxia Neonatorum, Hypoxia, Encephalopathy, Seizures
- Trial name
- NCT00147030
- Testing
- Whole body mild induced hypothermia
- Where
- United Kingdom
- Volunteers
- 325 people
- Sponsor
- Imperial College London
Fever
Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
The primary objective of the study is to determine the superiority of a single dose of intravenous ibuprofen compared to acetaminophen for the treatment of fever during the first two hours of treatment.
- Trial name
- NCT01002573
- Testing
- ibuprofen, acetaminophen
- Where
- 17 sites in United States
- Volunteers
- 118 people
- Sponsor
- Cumberland Pharmaceuticals
Native and Valve in Valve Aortic Valve Failure
Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation
Background: TAVR is a common therapy for people with heart problems. It stands for transcatheter aortic valve replacement, TAVR can be a better option than surgery. But it isn t safe for everyone.
- Trial name
- BASILICA (NCT03381989)
- Testing
- ASHI_INTECC Astato XS 20 0.014 guidewire
- Where
- 4 sites in United States
- Volunteers
- 31 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pain, Fever
Safety and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
The primary objective of this study is to evaluate the pharmacokinetic profile of a single dose of intravenous ibuprofen administered over approximately ten (10) minutes.
- Trial name
- NCT02583399
- Testing
- Ibuprofen
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Cumberland Pharmaceuticals
Body Temperature Changes
Cooling Vest May Reduce Heat Stress During Surgery
The investigators will propose a randomized cross-over trial using a uniform and strongly balanced 4-period design in which will include four operations for each surgeon.
- Trial name
- NCT04511208
- Testing
- Cooling Vest, Without cooling vest
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Spinal Cord Injuries
A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia
Persons with higher levels of spinal cord injury (above the 6th thoracic vertebrae: Hi-SCI) are unable to maintain their core body temperature (Tcore) within the normal range (97.5-99.7 °F) when exposed to warm environments.
- Trial name
- NCT05441449
- Testing
- Cooling Vest
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development