Clinical trials: Temporomandibular Disorder (TMD), open to volunteers
Chronic TMD Pain, Temporomandibular Disorder
R01_Pilot Jaw Muscle Phenotypes
The proposed study will assess the effect of local heat therapy on jaw pain and jaw fatigue secondary to a teeth clenching task in chronic TMD pain cases.
- Trial name
- NCT07153107
- Testing
- Local Heat Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMD), TMJ Disorder
Machine Learning for Evaluating and Diagnosing Temporomandibular Disorders
This study aims to improve clinical efficiency and effectiveness in treating Temporomandibular Disorders (TMD). The researchers will integrate machine learning technology with clinical examination data, CBCT, and MRI to identify…
- Conditions
- Temporomandibular Disorders (TMD), TMJ Disorder, TMJ Pain
- Trial name
- NCT07771296
- Testing
- Low-Level Laser Acupuncture, Proprioceptive Training, Stabilization Splint Treatment
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- En Chu Kong Hospital
Temporomandibular Disorders (TMD)
INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR
Temporomandibular disorders (TMD) encompass all temporomandibular muscular and osteoarticular conditions. TMD affects 31% of the adult population, with chronic, debilitating pain in 10% of cases.
- Trial name
- DiagDTM (NCT07499869)
- Testing
- digital jaw impressions and Modjaw® records
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Disc Degenerative Disease, Spine Degeneration
Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints
Study Summary: Effectiveness of Physiotherapy and Osteopathy in Treating Spinal and Temporomandibular Joint Pain About the Study and Its Objective This study is conducted by Artur Hołodniuk, MSc, a physiotherapist and academic…
- Conditions
- Disc Degenerative Disease, Spine Degeneration, Back Ache, Temporomandibular Disorder (TMD)
- Trial name
- NCT07830836
- Testing
- General Osteopathic Treatment, Visceral Therapy, Magnetic field therapy
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
TMD, Temporomandibular Disorders (TMDs)
Effects of Vagus Nerve Stimulation on Temporomandibular Disorders.
The study aims to examine the effects of transcutaneous non-invasive vagus nerve stimulation (nVNS) on symptoms and brain mechanisms in premenopausal women with temporomandibular disorders (TMD).
- Trial name
- NCT07288411
- Testing
- nVNS Treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Arpana Church
Temporomandibular Disorder (TMD)
Marine Lipids Ease Painful TMD
The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic…
- Trial name
- ADAPT (NCT07437313)
- Testing
- SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Temporomandibular Disorders (TMD), Pregnancy
Evaluation of Temporomandibular Disorders During Pregnancy
This study aims to evaluate how temporomandibular disorders (TMD) - a condition affecting the jaw joint and chewing muscles - change during pregnancy.
- Trial name
- NCT07791173
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Zeynep Serra Kalkan
Temporomandibular Disorders (TMD)
Feasibility and Acceptability of OLP-EXP in Chronic Pain
The primary objective is to determine the feasibility of delivering OLP-EXP, EXP only, and OLP only over 6 weeks to adults with chronic TMD.
- Trial name
- NCT07735520
- Testing
- OLP-EXP, OLP, EXP
- Volunteers
- 57 people
- Sponsor
- University of Maryland, Baltimore
Temporomandibular Disorders (TMD), Internal Derangement of the Tempromandibular Joint
Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Temporomandibular Disc Displacement
This study aims to rigorously assess the effectiveness of LPCGF in the management of internal disc displacement in patients with TMD through a randomized clinical trial.
- Conditions
- Temporomandibular Disorders (TMD), Internal Derangement of the Tempromandibular Joint, Anterior Disc Displacement
- Trial name
- LPCGF in TMDs (NCT07075276)
- Testing
- Liquid Phase Concentrated Growth Factor, Conventional arthrocentesis
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Horus University
Chronic Temporomandibular Disorders (TMD)
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases.
- Trial name
- TMD-CPM (NCT06617494)
- Testing
- Pain modulation testing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction
Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.
The goal of this clinical trial is to evaluate the long-term outcome of surgical intervention (arthroscopy or discectomy) due to the diagnoses temporomandibular joint disc displacement with or without displacement.
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Joint Disc Displacement, Without Reduction
- Trial name
- NCT06782165
- Testing
- Arthroscopy & saline irrigation alone, Discectomy
- Where
- Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Temporomandibular Joint Disc Displacement, Temporomandibular Joint Disc Displacement, Without Reduction
TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction
The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention arthrocentesis in treating disabling and painful temporomandibular joint disc displacement without reduction.
- Conditions
- Temporomandibular Joint Disc Displacement, Temporomandibular Joint Disc Displacement, Without Reduction, Temporomandibular Disorders (TMD)
- Trial name
- ACALL (NCT06782178)
- Testing
- Arthroscopic lysis and lavage, Arthrocentesis/Saline
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Disorders (TMD)
TMJ Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction.
The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention operative arthroscopy in treating disabling and painful temporomandibular joint disc displacement with reduction.
- Trial name
- ALLOAA (NCT06782191)
- Testing
- Arthroscopic lysis and lavage, Operative arthroscopy
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Karolinska Institutet
Temporomandibular Disorders (TMD), Manual Therapy
Effectiveness of the Fascial Distortion Model in Temporomandibular Disorders: A Randomized Sham-controlled Trial
The aim of the study was to investigate the effectiveness of Manual Therapy Based on the Fascial Distortion Model in individuals with temporomandibular disorders compared to sham control.
- Conditions
- Temporomandibular Disorders (TMD), Manual Therapy, Fascial Distortion
- Trial name
- NCT06627855
- Testing
- Fascial Distortion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Temporomandibular Disorder (TMD)
JIT: Effect of Pain on DT in TMD
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in…
- Trial name
- TMD (NCT06659991)
- Testing
- alcohol condition, control condition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMD)
Aerobic Physical Activity and Orofacial Myofascial Pain
Orofacial myofascial pain, most commonly represented by Temporomandibular Disorders (TMD) a significant public health, affecting approximately 12% to 14% of the general population.
- Trial name
- AERODOF (NCT07526688)
- Testing
- Temporal Summation of Pain and Questionnaire
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Temporomandibular Disorders (TMD)
Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain
The goal of this clinical trial is to learn whether a 2-week gratitude journaling activity is feasible and acceptable for individuals with Temporomandibular Disorder (TMD) and chronic overlapping pain.
- Trial name
- NCT06977100
- Testing
- Gratitude, General Wellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
TMJ Disc Disorder, Temporomandibular Joint Disc Displacement, Without Reduction
Arthroscopic Lysis and Lavage With and Without Intra-articular Injection of Hyaluronic Acid in Patients With DDwoR in TMJ
The study aims to assess the outcomes of arthroscopic lysis and lavage procedure with and without single intra-articular injection of hyaluronic acid in managing patients with anterior disc displacement without reduction.
- Conditions
- TMJ Disc Disorder, Temporomandibular Joint Disc Displacement, Without Reduction, TMD/Orofacial Pain, Temporomandibular Disorder
- Trial name
- NCT07614932
- Testing
- Arthroscopic lysis and lavage, arthroscopic lysis and lavage with intra-articular injection of hyaluronic acid
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Temporomandibular Disorders (TMD)
Ultrasound Versus Virtual Reality on Temporomandibular Disorder
The Purpose of the study is to compare between the therapeutic efficacy of ultrasound and VR in decreasing pain and improving ROM for Patients with temporomandibular joint disorder after tooth extraction surgery.
- Trial name
- NCT07575633
- Testing
- ultrasound, virtual reality
- Volunteers
- 50 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid