Clinical trials: Temporomandibular Joint
Stroke, Mastication Disorder
Expiratory Muscle Training in Stroke
Stroke affects the vital activities of daily living such as breathing and swallowing. After stroke excursion of the diaphragm reduces about 50%, and also the maximum expiratory pressure of the individual 50% or higher.
- Conditions
- Stroke, Mastication Disorder, Temporomandibular Disorders, Dysphagia
- Trial name
- NCT04569968
- Testing
- Expiratory muscle training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Abant Izzet Baysal University
Temporomandibular Joint Dysfunction Syndrome, Chronic Pain
Restoring Masticatory Function to Treat Chronic Pain
The primary endpoint will be the average change in pain score from baseline to the three- and six-month assessments. Efficacy will be demonstrated by superior pain relief with the active treatment compared with the placebo.
- Trial name
- MAP (NCT02144233)
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 77 people
- Sponsor
- Urbano Santana Penin, MD, DDS, PhD
Temporomandibular Joint Disorders, Orofacial Pain
Occlusal Adjustment as Treatment for Chronic Orofacial Pain
The purpose of this study is to determine whether occlusal adjustment by selective grinding and/or occlusal addition is an effective treatment of chronic temporomandibular joint disorders.
- Trial name
- NCT00899717
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 21 people
- Sponsor
- University of Santiago de Compostela
Temporomandibular Disorders
Treatment Outcomes for Temporomandibular Disorders (TMD) Via the Clayton Intra-aural Device (CID) Clinical Trial
The purpose of this study is to characterize the safety profile and assess the effectiveness of the CID in treating subjects with temporomandibular disorders (TMDs).
- Trial name
- NCT00815776
- Testing
- Clayton Intra-aural Device (CID), Mouth Splint, Exercise Group
- Where
- Mexico
- Volunteers
- 152 people
- Sponsor
- Ascentia Health, Inc.
Temporomandibular Joint Dysfunction Syndrome
Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial
Introduction. Temporomandibular disorders (TMD) are a group of conditions that are multifactorial in nature, and it primarily presents with symptoms of pain and decreased functional capacity.
- Trial name
- NCT02295644
- Testing
- Ultrasound Sonicator 740
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- State University of New York at Buffalo
Temporomandibular Joint Disorders
Motor Cortex as a Research & Therapeutic Target in TMD
The investigators are doing a study to learn about the effects of a type of low-energy non-surgical electrical brain stimulation (HD-tDCS) on chronic pain in people's jaw joints.
- Trial name
- NCT02247063
- Testing
- High-Definition Transcranial Direct Current Stimulation (HD-tDCS)
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Temporomandibular Disorders
Conservative Treatment of Patients With Temporomandibular Disorders
At any given time, 10 million Americans suffer from temporomandibular disorders (TMD), with a lifetime prevalence of 45% and costs for direct care exceeding $2 billion/year.
- Trial name
- D1P2-TMD (NCT01021306)
- Testing
- Chiropractic w/Activator & Self Care, Dental Care & Self Care, Self-Care Only Group
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Palmer College of Chiropractic
Temporomandibular Joint Dysfunction Syndrome, Burning Mouth Syndrome
Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain
Patients with chronic masticatory muscle pain (i.e., pain greater than three months) or patients with burning mouth syndrome participate in this study.
- Trial name
- NCT00716807
- Testing
- nalbuphine plus naloxone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of California, San Francisco
Temporomandibular Disorders
Study of Orofacial Pain and PropRANOlol
Purpose: Primary: To evaluate the efficacy of extended-release (ER) propranolol compared to placebo in the reduction of a pain index in patients with temporomandibular disorder (TMD).
- Trial name
- SOPPRANO (NCT02437383)
- Testing
- Propranolol ER
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of North Carolina, Chapel Hill
Pain
Efficacy of Steroid Supplementation After TMJ Rinsing for Pain Management
The hypothesis to be tested is temporomandibular joint (TMJ) rinsing followed by steroid injection is more efficacious than a placebo injection based on standard pain and physical measures that are recorded before and after…
- Trial name
- NCT01770912
- Testing
- Lactated Ringers, Triamcinolone hexacetonide
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Florida
Impacted Third Molar Tooth, Temporomandibular Disorder
Assessing a New Jaw Support Device During Third Molar Extractions
During mandibular 3rd molar (wisdom tooth) extractions, when a downward force is placed on the patient's jaw, the patient must tense his/her jaw muscles to oppose it.
- Trial name
- NCT03975920
- Testing
- The Restful Jaw Device
- Where
- 4 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Joint Disorders
Intra-articular Injection in Arthroscopic Management of Temporomandibular Diseases
The aim of this study is to evaluate the efficacy of intra-articular injection of platelet rich plasma versus hyaluronic acid following diagnostic arthroscopy in the management of patients suffering from degenerative…
- Trial name
- NCT04936945
- Testing
- Temporomandibular joint arthroscopy plus intra-articular injection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Temporomandibular Disorder
Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain
Temporomandibular disorders (TMDs) are one of the most common muco-skeletal disorders, seen in the dental clinics. Many factors work together to initiate or aggravate the condition, so it is a multifactorial disorder.
- Trial name
- NCT04066426
- Testing
- naproxen sodium+codeine phosphate, naproxen sodium+dexamethasone, naproxen sodium, paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Yuzuncu Yil University
Vestibulodynia, Temporomandibular Disorder
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT03844412
- Testing
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Temporomandibular Disorders
Biofeedback-Based Cognitive Behavioral Treatment for Temporomandibular Disorders
The purpose of this study is to develop and evaluate a biofeedback-based cognitive behavioral treatment for patients with chronic temporomandibular disorders using a randomized controlled design.
- Trial name
- NCT00769561
- Testing
- Biofeedback-Based Cognitive Behavioral Treatment, Dental treatment with occlusal splint (OS)
- Where
- 2 sites in Germany
- Volunteers
- 58 people
- Sponsor
- Philipps University Marburg
Temporomandibular Disorders (TMD)
Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for Acute Treatment of Temporomandibular Disorders
The purpose of this study is to compare the efficacy and safety of rimegepant versus placebo in the acute treatment of Temporomandibular Disorders (TMD), which are medical conditions involving the temporomandibular joint (the…
- Trial name
- NCT05262517
- Testing
- Rimegepant
- Where
- 32 sites in United States
- Volunteers
- 126 people
- Sponsor
- Pfizer
Temporomandibular Joint Disorders
Acute Effects of Alcohol Use on Chronic Orofacial Pain
Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions…
- Trial name
- NCT04019093
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Florida
Temporomandibular Joint Disorders
Duloxetine for Treatment of Painful Temporomandibular Joint Disorder
Temporomandibular joint disorders (TMJD) are a family of musculoskeletal disorders that represent the most common chronic orofacial pain condition.
- Trial name
- NCT00981149
- Testing
- duloxetine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Bruxism, Sleep Bruxism, Adult
Comparison of Dry Needling and Two Botulinum Toxins for Bruxism
1. Aim: The aim of this study is to prospectively compare the clinical efficacy of Dry Needling (DN), Nabota (PrabotulinumtoxinA), and Dysport (AbobotulinumtoxinA) treatments on the thickness of masseter and anterior temporal…
- Conditions
- Bruxism, Sleep Bruxism, Adult, Awake Bruxism, Masseter Muscle Hypertrophy
- Trial name
- NCT07452510
- Testing
- Dry Needling (DN), PrabotulinumtoxinA, Abobotulinumtoxina
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Tayyip Erdogan University
Temporomandibular Joint Dysfunction, Pain
A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction
The purpose of this study is to determine whether the administration of hyaluronic acid or corticosteroid during arthrocentesis of the temporomandibular joint provides additional pain relief and improved function.
- Conditions
- Temporomandibular Joint Dysfunction, Pain, Arthrocentesis
- Trial name
- NCT01524913
- Testing
- Hyaluronic acid, Corticosteroid, Lactated Ringers
- Where
- 5 sites in United States
- Volunteers
- 102 people
- Sponsor
- Emory University