Clinical trials: Tendinopathy
Tendinopathy
Study of Efficacy, Safety and Tolerability of AIN457 in Patients With Active Overuse Tendinopathy
This was a randomized, double-blind, placebo-controlled, multi-center, Phase II study of s.c. secukinumab 300 mg in 98 randomized patients with overuse rotator-cuff tendinopathy without systemic inflammatory disease.
- Trial name
- NCT03344640
- Testing
- secukinumab
- Where
- 12 sites in United States, Czechia and 3 more
- Volunteers
- 96 people
- Sponsor
- Novartis Pharmaceuticals
Epicondylitis
Treatment of Epicondylitis by Ultrasound-guided Local Injections of PRP (Platelet Rich Plasma)
The purpose of this study is to assess efficacy of two intra-tendinous injections of platelet-rich plasma (PRP) on epicondylitis of recent evolution (≤ 3 months) compared compared to two intra-tendinous injections of saline…
- Trial name
- NCT02378285
- Testing
- ACP, Saline solution
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Arthrex SAS
Ankle Sprain, Back Pain
Counterpain PXM Versus Diclofenac Versus Piroxicam
The goal of this clinical trial is to learn if a gel containing Piroxicam plus Counterirritant (warming/cooling ingredients) is as effective and safe as two other common anti-inflammatory gels for treating acute muscle, bone, and…
- Conditions
- Ankle Sprain, Back Pain, Osteoarthritis (OA) of the Knee, Tennis Elbow
- Trial name
- NCT07475663
- Testing
- Piroxicam plus Counterirritant (brand name Counterpain® PXM)., Diclofenac Sodium 10 mg (Brand Name Hotin® DCL), Piroxicam 0.5% (Brand name Pirofel® gel)
- Where
- Indonesia
- Volunteers
- 180 people
- Sponsor
- Taisho Pharmaceutical Indonesia
Bursitis, Tendinitis
Efficacy and Safety of Etoricoxib/Betamethasone Combination in Acute Bursitis, Tendinitis and Synovitis
Phase III, multicenter, prospective, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of a fixed-dose combination of etoricoxib/betamethasone compared with etoricoxib alone in patients with an…
- Conditions
- Bursitis, Tendinitis, Synovitis
- Trial name
- NCT07328022
- Testing
- Fixed Dose Etoricoxib + Betamethasone, Monotherapy Etoricoxib
- Where
- Mexico
- Volunteers
- 89 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Achilles Tendinopathy
The Efficacy of Tendoactive, Eccentric Training, and the Combination of Both as a Treatment of Achilles Tendinopathy
The purpose of this study is to determine whether Tendoactive, eccentric training, or the combination or both could be effective in the treatment of Achilles tendinopathy.
- Trial name
- Tendoactive (NCT01691716)
- Testing
- Tendoactive, Eccentric training
- Where
- 6 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Bioiberica
Hepatotoxicity, Tenosynovial Giant Cell Tumor
A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment
A study to evaluate the long-term risk of hepatic failure with TURALIO™ (pexidartinib) and the mechanism of liver injury based upon optional liver biopsy information among patients who received or are receiving TURALIO™…
- Trial name
- NCT04635111
- Testing
- TURALIO™
- Where
- 8 sites in United States
- Volunteers
- 30 people
- Sponsor
- Daiichi Sankyo
Greater Trochanteric Pain Syndrome, GTPS - Greater Trochanteric Pain Syndrome
Evaluation of the Efficacy of the Use MD Tissue Collagen Medical Device in the Infiltrative Treatment of Greater Trochanter Pain Syndrome (GTPS)
Greater Trochanteric Pain Syndrome, also known as GTPS (Greater Trochanteric Pain Syndrome) is a complex clinical condition characterized by chronic and recurrent pain in the lateral region of the hip, near the greater trochanter…
- Conditions
- Greater Trochanteric Pain Syndrome, GTPS - Greater Trochanteric Pain Syndrome, Tendon Disorder, Pertrochanteric Fracture
- Trial name
- MEDANTRO (NCT05486078)
- Testing
- MD Tissue Collagen Medical Device
- Where
- Italy
- Volunteers
- 47 people
- Sponsor
- Guna S.p.a
Rotator Cuff Tendinitis, Syndrome Rotator Cuff
Performance and Safety Evaluation of MD-Shoulder Collagen Medical Device in the Treatment of Rotator Cuff Syndrome
Rotator Cuff Syndrome is a commonly encountered musculoskeletal disorder in clinical practice, with an incidence ranging from 0.3% to 5.5%, and an annual prevalence of 0.5% to 7.4%.
- Conditions
- Rotator Cuff Tendinitis, Syndrome Rotator Cuff, Tendinopathy, Tendinoses, Rotator Cuff
- Trial name
- ROPIRAMED (NCT05489484)
- Testing
- MD-Shoulder Collagen Medical Device
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Guna S.p.a
Tendinopathy
Achilles Tendon Repair With Bioinductive Implant
To evaluate bioinduction of new tissue and tendon healing after implantation of the Rotation Medical Bioinductive Implant used as adjunct to surgical repair in the treatment of insertional Achilles tendonitis.
- Trial name
- NCT02811003
- Testing
- Rotation Medical Bioinductive Implant
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Smith & Nephew, Inc.
Pigmented Villonodular Synovitis, PVNS
MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS)
This study, designed as a proof of concept study of MCS110 in pigmented villonodular synovitis, assessed the clinical response to MCS110 treatment in Pigmented Villonodular Synovitis (PVNS) patients, after a single or multiple…
- Conditions
- Pigmented Villonodular Synovitis, PVNS, Giant Cell Tumor of the Tendon Sheath, GCCTS
- Trial name
- NCT01643850
- Testing
- MCS110
- Where
- 8 sites in United States, Switzerland
- Volunteers
- 36 people
- Sponsor
- Novartis Pharmaceuticals
Achilles Tendinopathy
The Value of Platelet-Rich Plasma in Chronic Midportion Achilles Tendinopathy: a Double-blind Randomized Clinical Trial
The study will be a double-blind randomized single-center clinical trial comparing 3 treatment groups with chronic midportion Achilles tendinopathy.
- Trial name
- PRICT (NCT00761423)
- Testing
- PRP Injection with eccentric exercises
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Zimmer Biomet
Tendinosis, Tendinopathy
Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis
The primary purpose of this study is to assess the safety profile of RCT-01 injections as compared to placebo injections. This study will also measure the impact these injections will have on tendon structure and function and the…
- Trial name
- ReaCT (NCT02330146)
- Testing
- RCT-01
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- RepliCel Life Sciences, Inc.
Non Ruptured Tendon Injuries, Tendinopathy
Tissue Repair Device (VergenixTM STR) in Patients With Epicondylitis (Tennis Elbow)
The VergenixTM STR device is intended for the repair of non ruptured tendon injuries (Tendinopathy).
- Trial name
- CP-STR-01 (NCT02309307)
- Testing
- Tissue Repair Device (VergenixTM STR)
- Where
- 3 sites in Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Collplant
Bankart Lesions, SLAP Lesion
PMCF Study on the Safety, Performance and Clinical Benefits Data of the ToggleLoc™ 2.9mm and JuggerLoc™ in the Shoulder
The study is a multicenter, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to collect data confirming safety, performance and clinical benefits of the…
- Conditions
- Bankart Lesions, SLAP Lesion, Acromioclavicular; Dislocation, Capsular Shift/Capsulolabral Reconstruction
- Trial name
- NCT05584553
- Testing
- ToggleLoc 2.9 mm soft tissue device, JuggerLoc soft tissue device
- Where
- 3 sites in United States, Spain
- Volunteers
- 214 people
- Sponsor
- Zimmer Biomet
Lateral Epicondylitis
Recover L-PRP in Lateral Epicondylitis (REGP-11-00)
The objective of the study is to further characterize the performance of L-PRP prepared using the Biomet Recover Kit in the treatment of chronic LE.
- Trial name
- NCT02588040
- Testing
- Leukocyte- and Platelet-Rich Plasma (L-PRP)
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Zimmer Biomet
Tenosynovial Giant Cell Tumor
MOVE: Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib
The goal of this observational study is to better understand real-world use of vimseltinib, treatment patterns, and health-related quality of life in participants treated with vimseltinib for TGCT.
- Trial name
- MOVE (NCT07075471)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Deciphera Pharmaceuticals, LLC
Tendon Injuries, Musculoskeletal Pain
Long Duration Therapeutic Ultrasound on Tendon Injuries
Human clinical trial to measure the effect of long duration therapeutic ultrasound on tendon injuries. The hypothesis is that use of long duration ultrasound will relieve pain, increase tendon strength, and improve quality of…
- Trial name
- NCT02340273
- Testing
- Therapeutic ultrasound
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- ZetrOZ, Inc.
Trigger Finger, Hyaluronic Acid
Evaluate the Effectiveness of Crosslinked HA on the Adhesion Preventing After Trigger Finger Release Surgery
To Evaluate the Effectiveness of the use of a Novel Crosslinking Hyaluronan Hydrogel on the Prevention of the Adhesion Occurrence After Trigger Finger Release Surgery
- Trial name
- NCT05082480
- Testing
- Hyaluronic acid (HA), Saline
- Where
- 2 sites in Taiwan
- Volunteers
- 5 people
- Sponsor
- SciVision Biotech Inc.
Tendinosis, Tendinopathy
Long-Term Follow-up of the Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis
The primary purpose of this study is to assess the long-term safety profile of RCT-01 injections as compared to placebo injections.
- Trial name
- ReaCT-X (NCT02655042)
- Where
- Canada
- Sponsor
- RepliCel Life Sciences, Inc.
Rotator Cuff Tendinopathy
Clinical Benefits and Safety of Tropho Tend in the Management of Painful Rotator Cuff Tendinopathy
This is a prospective, open label, controlled, exploratory clinical investigation aimed to evaluate the clinical benefit and safety of Tropho Tend in the conservative management of painful Rotator Cuff Tendinopathy (RCT).
- Trial name
- NCT06809543
- Testing
- Polynucleotides (Tropho Tend), Rehabilitation physiotherapy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Mastelli S.r.l