Clinical trials: Tendinopathy
Posterior Tibial Tendon Dysfunction
Bracing and Strengthening for Posterior Tibial Tendon Dysfunction
Posterior tibial tendon dysfunction (PTTD) is a problem with the tendon connecting one of the lower leg muscles to the foot bone. PTTD can cause pain, swelling, and a flattened foot and may require surgery if left untreated.
- Trial name
- NCT00756457
- Testing
- Bracing, Strengthening exercises, Stretching exercises
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ithaca College
Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis
Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)
The goal of this clinical trial is to assess the efficacy and safety of Pimicotinib (ABSK021) in patients with Tenosynovial Giant Cell Tumor (TGCT).
- Conditions
- Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath
- Trial name
- NCT05804045
- Testing
- Pimicotinib(ABSK021)
- Where
- 40 sites in United States, Canada and 5 more
- Volunteers
- 94 people
- Sponsor
- Abbisko Therapeutics Co, Ltd
Musculoskeletal Pain, Osteoarthritis
Clinical Outcomes of Autologous Bone Marrow Aspirate Concentrate Injections for Musculoskeletal Conditions
The use of Bone Marrow Autologous Collection (BMAC) in musculoskeletal conditions including osteoarthritis and tendon injuries has been growing. Outcome evidence continues to be sparse.
- Conditions
- Musculoskeletal Pain, Osteoarthritis, Tendinopathy, Sprains Strain
- Trial name
- NCT02981394
- Testing
- Bone Marrow Aspirate Concentrate Injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Lateral Epicondylitis
Blood Flow Restriction & Tennis Elbow Rehab
Lateral epicondylitis (LE), often referred to as "tennis elbow" is a common and debilitating overuse injury affecting 1-3% of adults annually.
- Trial name
- NCT05237869
- Testing
- Blood Flow Restriction Device, Standard Physical Therapy
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Julie Nuelle
Trigger Finger
Early Postoperative Function After Open Versus Ultrasound-Guided Trigger Finger Release
Clinical outcomes after open trigger finger release are excellent. Minimally invasive techiques with ultrasound guidance theoretically offer advantages for faster recovery but this technique has not been compared prospectively…
- Trial name
- NCT07364695
- Testing
- UltraGuideTFR (Sonex Health, MN, USA)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Tendinopathy
Exercise With Individual Dosage Against the Best Current Practice in Lower Limb Tendinopathy (MaLaGa Trial)
This study compares the effect of a therapeutic physical exercise programme based on an individualized control of the exercise dose by monitoring the force-speed curves against the current best practice in the treatment of…
- Trial name
- MaLaGa (NCT03853122)
- Testing
- Best current practice exercise programme, Experimental exercise programme
- Volunteers
- 104 people
- Sponsor
- University of Malaga
Lateral Epicondylitis, Tennis Elbow
Comparison of Three Physiotherapy Approaches in Lateral Epicondylitis Treatment
This study aimed to compare the efficacy of physiotherapy alone (PTA), Kinesiotaping (KT) combined with physiotherapy (KTPT), and wrist rest splint combined with physiotherapy (PTWJRS) treatments for the treatment of LE
- Trial name
- NCT07789886
- Testing
- Physiotherapy Program, Kinesiotaping (KT), Wrist Joint Rest Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Medipol University
Lateral Epicondylitis (Tennis Elbow)
Dry Needling vs ESWT in Lateral Epicondylitis
This randomized single-blind controlled trial aims to compare the effectiveness of ultrasound-guided dry needling and extracorporeal shock wave therapy in patients with lateral epicondylitis.
- Trial name
- NCT07550322
- Testing
- Ultrasound-guided dry needling, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Lateral Epicondylitis
Scapular PNF Versus Shoulder Strengthening Exercises in Patients With Lateral Epicondylitis.
The purpose of this study is to compare between the effect of scapular proprioceptive neuromuscular facilitation versus shoulder and scapular strengthening exercise on pain, functional outcome and grip strength in patients with…
- Trial name
- PNF (NCT05947968)
- Testing
- Scapular PNF, Shoulder strengthening exercises
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mahmoud Essam Abu Elfetouh Ghallab
De Quervain Syndrome
Mobilization With Movement Versus Soft Tissue Mobilization in Patients With De Quervain Tenosynovitis
this study will investigate the effects of mobilization with movement in addition to soft tissue mobilization on pain and range of motion in patients suffering from De Quervain Tenosynovitis.
- Trial name
- NCT05356624
- Testing
- Mulligan Mobilization, Soft Tissue Mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Lateral Epicondylitis
Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia
The purpose of this research is to compare two different approaches for treating patients with lateral epicondylalgia: electric dry needling, thrust manipulation and stretching versus impairment-based manual therapy, exercise and…
- Trial name
- NCT03167710
- Testing
- Dry Needling, manipulation, stretching, manual therapy, exercise, ultrasound
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Trigger Finger Disorder
Effect Of Dry Needling On Quality Of Life In Patients With Trigger Fingers
This study will be conducted to investigate the effect of dry needling on quality of life in patients with trigger finger
- Trial name
- NCT05671523
- Testing
- Dry needling, conventional treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
Platelet Rich Plasma for Musculoskeletal Conditions
The primary purpose of this study is to follow patients with various musculoskeletal (MSK) conditions over a one-year follow-up period after receiving a platelet rich plasma (PRP) injection, assessing changes in their pain…
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder
- Trial name
- PRP for MSK (NCT07231471)
- Testing
- Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Tennis Elbow
Efficacy of Injection Therapy for Lateral Epicondylosis
While evidence does not identify any conventional therapy as definitive for chronic lateral epicondylosis (CLE, tennis elbow), basic science and limited pilot level trials support rigorous assessment of prolotherapy (PrT) and…
- Trial name
- NCT01476605
- Testing
- Dextrose prolotherapy, PrT-DMS, Platelet Rich Plasma injection
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Tenosynovial Giant Cell Tumor
Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Tenosynovial Giant Cell Tumor Surgery
This study evaluates the diagnostic accuracy of Indocyanine Green (ICG) fluorescence imaging in visualizing Tenosynovial Giant Cell Tumor (TGCT) lesions during surgery.
- Trial name
- ICG-TGCT (NCT07315841)
- Testing
- Indocyanine Green
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Rotator Cuff Tendinopathy, TECAR Therapy
The Effect of TECAR Therapy on Pain and Shoulder Function in Patients With Rotator Cuff Tendinopathy
Shoulder pain is one of the most common symptoms of musculoskeletal injuries; one-quarter of the general population and two-thirds of adults experience this problem at some point in their lives.Rotator cuff tendinopathy also…
- Conditions
- Rotator Cuff Tendinopathy, TECAR Therapy, Physical Therapy
- Trial name
- NCT07823933
- Testing
- tecar therapy, physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Ayşe Ukbe Baykut
Lateral Epicondylitis
Effectiveness of Chiropractic Cervical Manipulation in Lateral Epicondylitis
İt is aimed to examine the effect of chiropractic cervical manipulation on pain, functionality and grip strength in patients with lateral epicondylitis and whether it is preferable to placebo.
- Trial name
- NCT06300749
- Testing
- Chiropractic Cervical Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Mesut Arslan
Achilles Tendinopathy (AT)
Effect of Foot Position During Rehabilitation of Achilles Tendinopathy on Tendon Mechanics and Symptoms.
This study will investigate whether a 12-week load-based exercise program performed with an externally rotated foot position ("toes-out") leads to different changes in intra-tendinous sliding, symptoms, and function compared to a…
- Trial name
- NCT07623408
- Testing
- 12-week adaptive, load-based exercise therapy protocol for Achilles Tendinopathy
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- KU Leuven
Lateral Epicondylitis
Recover L-PRP in Lateral Epicondylitis (REGP-11-00)
The objective of the study is to further characterize the performance of L-PRP prepared using the Biomet Recover Kit in the treatment of chronic LE.
- Trial name
- NCT02588040
- Testing
- Leukocyte- and Platelet-Rich Plasma (L-PRP)
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Zimmer Biomet
To Evaluate the Efficacy and Safety of Selected TCM Elbow Manipulation in Treating, Lateral Epicondylitis
Efficacy and Safety of Selected Traditional Chinese Medicine Elbow Manipulation Versus Mill's Manipulation as Control for Lateral Epicondylitis
Background: Lateral epicondylitis (LE), also referred to as lateral elbow tendinopathy and tennis elbow, is commonly seen clinically as an orthopedic disease.
- Trial name
- NCT07843771
- Testing
- Selected Traditional Chinese Medicine manipulation, Mill's Manipulation
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University