Clinical trials: Tendon Injury
Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Reconstruction Made With Hamstring Tendon And Quadriceps Tendon Autografts
Anterior cruciate ligament reconstruction (ACLR) is one of the most common procedure all around the world, however optimal graft source for ACLR still remains controversial.
- Trial name
- NCT04940169
- Testing
- anterior cruciate ligament recontruction
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- SB Istanbul Education and Research Hospital
Rotator Cuff Tendinopathy
Effect of Plasma Rich in Growth Factors in Rotator Cuff Tendinopathy
The overall objective of the study is to assess the effectiveness of the treatment of degenerative rotator cuff tendinopathy using the application of plasma rich in growth factors (PRGF).
- Trial name
- NCT01915979
- Testing
- Plasma rich in growth factors (PRGF), Celestone cronodose (Bethametasone)
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Musculoskeletal Manipulations
Effects of Myofascial Release and TENS Over Pain, Hand Prehensile Strength and Functionality of Superior Extremity in Women With Lateral Epicondylalgia
This study evaluated the additive effect of myofascial release therapy on the brachial biceps on conventional management (TENS) in pain intensity, hand prehensile strength and upper limb functionality of individuals with lateral…
- Trial name
- NCT04023279
- Testing
- TENS, Myofascial therapy
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- Fernanda Merino Alvarez
Lateral Epicondylitis
Comparison of Intra-articular and Intra-tendinous Injections for Treatment of Lateral Epicondylitis
Lateral epicondylitis, commonly known as "tennis elbow" is a common cause of elbow pain encountered in primary care and specialty clinics.
- Trial name
- NCT02986646
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Missouri, Kansas City
Rotator Cuff Tear
LifeNet: Extracellular Matrix Graft in Rotator Cuff Repair
This trial is to evaluate the effectiveness of the ArthroFLEX® ECM scaffold graph as an augment in rotator cuff repair surgery to reduce the failure rate of rotator cuff repairs for large and massive rotator cuff tears.
- Trial name
- NCT03551509
- Testing
- ArthroFLEX ECM scaffold graft, Control, Alternative Treatment Group
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Gregory Gilot
Lateral Epicodylitis
Comparative Effects of Multiple Angle Isometrics vs Standard Isometric Exercise in Lateral Epicondylitis
Lateral Epicondylitis is one of the most common musculoskeletal conditions affecting 1-3% of population.Various terminologies are used to describe the disease like tendinitis of extensor carpi radialis brevis muscle (ECRB)…
- Trial name
- NCT07847034
- Testing
- Multiple Angle Isometrics Exercises, Standard Isometric Exercsises
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Ibadat International University, Islamabad
Contusions, Sprains
To Evaluate the Efficacy and Safety Aliviador Compared to Gelol in Patients With Contusions, Sprains, Trauma and Muscle Injury.
Multicenter, randomized, double-blind trial, to evaluate the efficacy and safety Aliviador compared to Gelol in the relief of signs and symptoms in patients with contusions, sprains, trauma and muscle injury start with less than…
- Conditions
- Contusions, Sprains, Trauma, Muscle Injury
- Trial name
- LBB-ALI-01/09 (NCT01097798)
- Testing
- Aliviador, Gelol
- Where
- 3 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Laboratorio Brasileiro de Biologia
Elasticity Imaging Techniques, Tendinopathy
Discriminative Validity of Strain Elastography of the Supraspinatus Tendon
This study aims at testing the discriminative validity of strain elastography in the normal and abnormal/pathological Supraspinatus tendon due to tendinopathy
- Conditions
- Elasticity Imaging Techniques, Tendinopathy, Rotator Cuff Tendinitis, Musculoskeletal Disease
- Trial name
- NCT03425344
- Testing
- Diagnostic
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karen Brage
Arthritis, Tendonitis
Prospective Analgesic Compound Efficacy (PACE) Study
A 24-week observational prospective study on the efficacy of topical non-steroidal anti-inflammatory drugs for the relief of pain.
- Conditions
- Arthritis, Tendonitis, Gout, Radiculopathy
- Trial name
- PACE (NCT02403687)
- Testing
- baclofen 2%, Bupivacaine hydrochloride 1%, Cyclobenzaprine hydrochloride 2%
- Volunteers
- 300 people
- Sponsor
- Express Specialty Pharmacy
Ligament Injury, Ligament; Laxity
Methylsulfonylmethane on Knee Laxity
The proposed research will focus on determining the effect of methylsulfonylmethane (MSM) on knee laxity changes through the menstrual cycle in young active females.
- Conditions
- Ligament Injury, Ligament; Laxity, Tendon Rupture, Tendon Injuries
- Trial name
- NCT03747198
- Testing
- methylsulfonylmethane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Patellar Tendinopathy
Effects of HMB and Rehabilitation Program in Athletes With Patellar Tendinopathy
This randomized, double-blind, placebo-controlled clinical trial evaluates the effects of oral beta-hydroxy-beta-methylbutyrate (HMB) supplementation combined with an eccentric exercise and extracorporeal shockwave rehabilitation…
- Trial name
- HMB_TEN (NCT07466407)
- Testing
- Eccentric exercise and extracorporeal shock wave therapy, Beta-hydroxy-beta-methylbutyrate (HMB)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Rotator Cuff Tear
A Randomized Clinical Trial Comparing Open to Mini-Open Rotator Cuff Repair for Full-Thickness Rotator Cuff Tears.
This study compares standard open rotator cuff repair versus arthroscopic mini-open rotator cuff repair by measuring the disease-specific quality of life at 2 years in patients with full thickness rotator cuff tears.
- Trial name
- NCT00251147
- Testing
- Open acromioplasty with rotator cuff repair, Arthroscopic acromioplasty with mini-open repair
- Where
- 4 sites in Canada
- Volunteers
- 73 people
- Sponsor
- University of Calgary
Anterior Cruciate Ligament Injury, Knee Injuries
Sensory Deficit Following ACL Reconstruction: PRF Pilot Study
Pilot, single-center, non-randomized, parallel-group clinical study designed to assess whether intraoperative application of autologous platelet-rich fibrin (PRF) at the bone-patellar tendon-bone (BPTB) donor site reduces…
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injuries, Sensory Disorders, Bone-Patellar Tendon-Bone Autograft
- Trial name
- PRF-ACL (NCT07257666)
- Testing
- Platelet-rich fibrin (PRF), Standard Closure (Control)
- Where
- Serbia
- Volunteers
- 53 people
- Sponsor
- University of Belgrade
Lateral Epicondylitis (Tennis Elbow)
Combined Isotonic Exercise in the Treatment of Lateral Epicondylitis
This study was designed to investigate the effectiveness of the combined isotonic exercise technique applied with extracorporeal shock waves in the treatment of lateral epicondylitis.
- Trial name
- NCT07170839
- Testing
- ESWT Aplication, ECCENTRIC EXERCISE, COMBINED ISOTONIC EXERCISE
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Shoulder Injuries, Shoulder Pain
Reverse Shoulder Arthroplasty vs Rotator Cuff Repair for 60+
To compare the one year outcomes between 60 year old patients with a three tendon tear treated as part of their standard of care with either a reverse total shoulder arthroplasty or rotator cuff repair surgery.
- Trial name
- RTSA-RCR (NCT06848023)
- Testing
- Reverse Total Shoulder Arthroplasty, Rotator Cuff Repair
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Campbell Clinic
Rotator Cuff Tear
InSpace™ System Over Rotator Cuff Repair in Comparison to Repair Alone.
This is a post-marketing study to further assess the safety and effectiveness of the InSpace™ in the study population in comparison to surgical RCT repair.
- Trial name
- NCT02210910
- Testing
- InSpace™ system over repair, Best Repair of torn Rotator Cuff
- Where
- Israel
- Volunteers
- 39 people
- Sponsor
- OrthoSpace Ltd.
Tendon Injury - Hand
Passive Mobilization With Place and Hold vs Active Mobilization Therapy After Flexor Tendon Repair
The aim of this study is to investigate if active mobilisation after flexor tendon repair in fingers gives better range of motion, strength, risk of rupture and patient satisfaction compared with passive mobilisation with place…
- Trial name
- NCT04385485
- Testing
- Active mobilisation, Passive mobilisation with place and hold
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Sahlgrenska University Hospital
Rotator Cuff Injuries
Predicting ROtator Cuff Tears Outcomes After Physical Therapy Treatment
The aim of this multicenter non-controlled study is to develop a multivariable prediction model of pain/disability improvements in patients with full-thickness rotator cuff tears, after a physical therapy treatment based on…
- Trial name
- PROTO (NCT05913050)
- Testing
- Therapeutic resistance exercise, Education
- Where
- Spain
- Volunteers
- 386 people
- Sponsor
- Hospital Universitario Fundación Alcorcón
Rotator Cuff Tendinitis
Study of 25% Dextrose Injections in Shoulder Ligaments and Tendons to Promote Their Healing
HYPOTHESIS: Prolotherapy, the injection of a growth promoting solution in injured ligaments and tendons of the shoulder is an effective treatment that decreases pain, increases functional capacity and promotes healing better and…
- Trial name
- Prolotherapy (NCT01402011)
- Testing
- 25% dextrose in shoulder entheses, .1% lidocaine in shoulder entheses, .1% lidocaine subcu. above shouldr enth.
- Where
- 2 sites in Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
DeQuervain's Tenosynovitis
Ultrasound-guided Injection for DeQuervain's
The investigators aim to perform a prospective study to evaluate the effectiveness of blind corticosteroid injections to US-guided injections for the treatment of de Quervain's disease.
- Trial name
- NCT02038634
- Testing
- Betamethasone, Ultrasound
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical College of Wisconsin
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