Clinical trials: Tendon Injury
Rotator Cuff Tear, Lateral Epicondylitis
Impact of Autologous Pure Platelet-rich Plasma in the Treatment of Tendon Disease
This is a randomized parallel controlled double-blind phase 2 clinical study.All subjects are recruited from the patients of rotator cuff tear, lateral epicondylitis or chronic achilles tendonitis.
- Conditions
- Rotator Cuff Tear, Lateral Epicondylitis, Achilles Tendinitis
- Trial name
- NCT03300531
- Testing
- Ultrasound-guided pure platelet-rich-plasma (P-PRP) injection, Ultrasound-guided platelet-rich-plasma (PRP) injection, Ultrasound-guided Compound betamethasone injection
- Volunteers
- 540 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Tennis Elbow, Lateral Epicondylitis
Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)
The investigators are testing the efficacy of a new, FDA-approved bioinductive patch in lateral epicondylitis (tennis elbow) patients.
- Trial name
- NCT03718637
- Testing
- Smith & Nephew Bioinductive Implant, Lateral Epicondylectomy, Ultrasound Imaging
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
Rotator Cuff Tear
Polydeoxyribonucleotide (PDRN) for Cuff Regeneration
This study is to evaluate the effect of polydeoxyribonucleotide (PDRN) for healing and fatty degeneration of rotator cuff. The investigators will enroll 130 patients with rotator cuff tear who will undergo arthroscopic rotator…
- Trial name
- NCT03916198
- Testing
- Polydeoxyribonucleotides, Normal saline
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Rotator Cuff Injury, Pain
Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene Block
Arthroscopic shoulder rotator cuff repair and acromioplasty are associated with severe postoperative pain. The interscalene block (ISB) is commonly used for this type of surgery, providing analgesia by anesthetizing the nerves…
- Trial name
- NCT02939209
- Testing
- Hydromorphone Hcl 2Mg Tab
- Where
- 2 sites in Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Vishal Uppal
Tennis Elbow
Effectiveness of Microcurrent for Treatment of Tennis Elbow
Tennis elbow is a relatively common musculoskeletal disorder that can cause significant pain and disability. Treatment of the disorder is not always successful, and it often recurs or becomes chronic.
- Trial name
- NCT00817232
- Testing
- Microcurrent (Elexoma Medic)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Hertfordshire
Rupture of Anterior Cruciate Ligament
Comparison of the Functional Outcome of Site Peroneus Longus Graft Donors With and Without Distal Stump Suturing of Peroneus Tendon Brevis on ACL Reconstruction Case in Cipto Mangunkusumo Hospital in Jakarta With 24 Patient as Subject Who Will Divide Into 2 Group.
Injury of the Anterior Cruciate Ligament (ACL) is one of the most common sports injuries. The incidence rate reaches 68.6 cases per 100,000 people per year.
- Trial name
- NCT04431063
- Testing
- Distal Stump Suturing
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Universitas Indonesia
Flexor Tendon Injuries of the Hand (Zones II-V)
The Effectiveness of Leap Motion-Based Virtual Reality in the Rehabilitation of Flexor Tendon Injuries of the Hand
This randomized controlled clinical trial aims to evaluate the effectiveness of a Leap Motion-based virtual reality rehabilitation program in patients who underwent surgical repair for flexor tendon injuries of the hand (zones…
- Trial name
- NCT07201740
- Testing
- Leap Motion-based Virtual Reality Therapy, Active Comparator - Routine Rehabilitation Only
- Volunteers
- 66 people
- Sponsor
- Kocaeli University
Rotator Cuff Injuries, Adhesions
Safety and Efficacy of Platelet-Rich Plasma Combined With Compound Betamethasone in Arthroscopic Surgery for Rotator Cuff Injury With Shoulder Adhesion: A Prospective, Multicenter, Randomized Controlled Trial
Background: Patients undergoing arthroscopic surgery for rotator cuff tears with shoulder adhesion often experience significant postoperative pain and stiffness.
- Trial name
- PRP+CB for RC (NCT07348016)
- Testing
- Liposomal Bupivacaine + Compound Betamethasone Injection, Compound Betamethasone Injection
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Rotator Cuff Tendinosis
Physiotherapy Treatment of Shoulder Rotator Cuff Tendinopathies. Global Postural Reeducation or Aerobic Exercise?
The goal of this clinical trial is to compare in participant population (patients with rotator cuff tendinopathy of the shoulder) the effect of a Global Postural Reeducation (GPR) program vs.
- Trial name
- NCT05613998
- Testing
- GPR Group, Aerobic Exercice Group
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Universidad Francisco de Vitoria
Rotator Cuff Injuries
Phase 1/2 Clinical Study of TPX-115 in Patients With Partial-Thickness Rotator Cuff Tear
Rotator cuff tear is one of the most common shoulder diseases and conservative treatment is commonly used for tears involving ≤50% of tendon thickness.
- Trial name
- NCT04470167
- Testing
- TPX-115
- Where
- 2 sites in South Korea
- Volunteers
- 49 people
- Sponsor
- Tego Science, Inc.
Rotator Cuff Injury, Anesthesia; Functional
The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane
Arthroscopic rotator cuff surgery of the shoulder is performed under general anesthesia. Pain control for after the surgery can be achieved purely with intravenous and oral pain medication or in combination with freezing of the…
- Trial name
- NCT03533452
- Testing
- Ropivacaine, Normal saline
- Where
- 2 sites in Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Rotator Cuff Tears, Rotator Cuff Tendinosis
Association Between Tendon-related Transcription Factor and Ultrasound Images and Shoulder Function
The purpose of this project is to extract effusions and damaged tendons during tendon repair therapy in patients with tendon tears.
- Trial name
- NCT04502134
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Lateral Epicondylitis
Comparison of Two Combined Therapeutic Methods for Treatment of Lateral Epicondylitis
To compare the effectiveness of two combined therapeutic methods including corticosteroid injections with elbow cast versus ice massage and non-steroidal anti inflammatory drugs (NSAIDs).
- Trial name
- NCT00554476
- Testing
- Triamcinolone Acetonide- Indomethacin-Cryotherapy-Casting
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Azad University of Medical Sciences
Shoulder Impingement, Frozen Shoulder
Relationship of Patient-Specific Functional Scale With Shoulder Functions: A Prospective Study
The aim of the study is to examine the relationship between the Patient- Specific Functional Scale (PSFS) and shoulder functions in the physiotherapy and rehabilitation program applied to patients with shoulder problems.
- Conditions
- Shoulder Impingement, Frozen Shoulder, Humeral Fractures, Rotator Cuff Tears
- Trial name
- NCT04538118
- Testing
- Shoulder disability, Shoulder Range of Motion, Pain Intensity
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Ankara Yildirim Beyazıt University
Lateral Epicondylitis
Trial of Blood Flow Restriction Plus Physical Therapy vs. Physical Therapy Alone for Lateral Epicondylitis
Open label randomized controlled trial comparing evidenced based physical/occupational therapy vs. physical/occupational therapy including blood flow restriction tourniquet in the treatment of lateral epicondylitis (tennis elbow).
- Trial name
- NCT03978897
- Testing
- Blood flow restriction tourniquet, Evidence based physical/occupational therapy
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Akron General
Rotator Cuff Tears
Comparison of Arthroscopic Supraspinatus Tendon Tear Repair in Patients Over 60 Years With and Without Patch Augmentation.
The aim of the study is to show that patch augmentation in rotatorcuff tear results in lower rate of recurrent tendon defects compared without patches.
- Trial name
- NCT03511547
- Testing
- Pitch Patch, ArthroFlex
- Sponsor
- Schulthess Klinik
Tennis Elbow
ITU Treatment for Chronic Epicondylitis Musculoskeletal Pain Reduction
This study evaluates the effectiveness, safety and patient tolerance for the use of Intense Therapeutic Ultrasound (ITU) for chronic, subcutaneous lateral Epicondylitis musculoskeletal tissue pain reduction began in July 2015 and…
- Trial name
- ITU (NCT03255733)
- Testing
- Intense Therapeutic Ultrasound Treatment
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Guided Therapy Systems
Rotator Cuff Injuries
Do Relaxation Exercises Decrease Postoperative Pain After Arthroscopic Rotator Cuff Repair?
The purpose of this study is to determine the effect of relaxation exercises on pain level and pain medication use after arthroscopic rotator cuff shoulder surgery
- Trial name
- NCT04249089
- Testing
- Relaxation video and pamplet
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Rothman Institute Orthopaedics
Wounds and Injuries
Study to Evaluate Polyheal-1 in Treatment of Recalcitrant Wounds
The objective of this study is to evaluate the performance of Polyheal-1 compared to Saline in the treatment of recalcitrant wounds including venous, post-operative and post-traumatic chronic wounds with different etiologies…
- Trial name
- NCT00552643
- Testing
- Suspension of polystyrene beads (POLYHEAL 1), Saline (0.9% NaCl)
- Where
- 6 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Polyheal Ltd.
Tendinopathy
Study of Efficacy, Safety and Tolerability of AIN457 in Patients With Active Overuse Tendinopathy
This was a randomized, double-blind, placebo-controlled, multi-center, Phase II study of s.c. secukinumab 300 mg in 98 randomized patients with overuse rotator-cuff tendinopathy without systemic inflammatory disease.
- Trial name
- NCT03344640
- Testing
- secukinumab
- Where
- 12 sites in United States, Czechia and 3 more
- Volunteers
- 96 people
- Sponsor
- Novartis Pharmaceuticals
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