Clinical trials: Terminal Care
Terminal Illness
Is Acupuncture Able to Reduce Nausea and Vomiting in the Terminal Ill Patient
A comparative effectiveness research design was used. The sample size was calculated to 136 patients, who were randomized to an intervention group and a control group respectively.
- Trial name
- NCT04378998
- Testing
- Acupuncture
- Volunteers
- 136 people
- Sponsor
- University of Aarhus
Advanced Cancer
Web-Based Advance Care Planning for Patients With Advanced Cancer
The goal of this clinical trial is to determine whether a web-based advance care planning (ACP) intervention can reduce preferences for aggressive life-sustaining treatments among patients with advanced cancer.
- Trial name
- NCT07712237
- Testing
- Web-Based Advance Care Planning Program, Patient Right to Autonomy Act Leaflet
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Heart Failure
Impact of Advance Care Planning on Care for Patients With Advanced Heart Failure
Aims: Advance care planning (ACP) is considered to be one of the most promising interventions to enable patients with life limiting illnesses to receive treatment at the end of life (EOL) according to their own preferences and to…
- Trial name
- NCT02299180
- Testing
- ACP
- Where
- 2 sites in Singapore
- Volunteers
- 282 people
- Sponsor
- Duke-NUS Graduate Medical School
Critical Illness, Ethics
Life Sustaining Treatments in Critically Ill Children
Summary of the Research on Withdrawing and Withholding Life-Sustaining Treatment for Critically Ill Children Background Medical treatments require regular evaluation to ensure they align with the patient's best interests…
- Conditions
- Critical Illness, Ethics, End of Life Care
- Trial name
- LST-Ped-Int (NCT07401420)
- Testing
- There is no intervention
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Advance Care Planning
Culturally-Adapting a Communication Intervention to Improve Palliative Care Literacy on Two Native American Reservations
This study will evaluate the feasibility, acceptability, and perceived effectiveness of the culturally-adapted COMFORT Communication Curriculum in two Native American reservation communities.
- Trial name
- NCT03569150
- Testing
- Cultural adaptation/implementation COMFORT CC
- Volunteers
- healthy volunteers welcome
- Sponsor
- South Dakota State University
End of Life Care, Violent Aggressive Behavior
Death, Dying, Violence and Aggression as Shown on Medical Television Series.
Medical TV dramas have become very popular in recent years. These shows are mainly created for entertainment and often do not reflect what really happens in hospitals.
- Conditions
- End of Life Care, Violent Aggressive Behavior, Television Viewing, Media Use
- Trial name
- NCT07416669
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 500 people
- Sponsor
- King's College Hospital NHS Trust
Cancer, Terminal Disease
Occupational Therapy Modulates the Pain in Cancer Patient Under Palliative Care
Pain is one of the most incapacitating symptoms because it is a complex experience that includes sensory and emotional perceptions, in which sensory, affective, cognitive, behavioral, cultural and social characteristics interact.
- Conditions
- Cancer, Terminal Disease, Pain
- Trial name
- NCT02102178
- Testing
- Tapestry, Regular occupation therapy, Weaving a scarf on a nail frame
- Volunteers
- 58 people
- Sponsor
- Barretos Cancer Hospital
End Stage Renal Disease, Depression
Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes
The objective of this study is to determine the effect of music therapy during dialysis on: depression, anxiety, quality of life, blood pressure, heart rate, medication compliance, compliance with dialysis treatment, number of…
- Conditions
- End Stage Renal Disease, Depression, Anxiety, Major Depressive Disorder
- Trial name
- NCT03925168
- Testing
- Music therapy
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Heart Failure, Heart-assist Devices
PCORI-1310-06998 Trial of a Decision Support Intervention for Patients and Caregivers Offered Destination Therapy Heart Assist Device
The left ventricular assist device (LVAD) is growing rapidly among people dying from end-stage heart failure who are unable to get a heart transplant.
- Trial name
- DECIDE-LVAD (NCT02344576)
- Testing
- DT LVAD Decision Support Intervention
- Where
- 6 sites in United States
- Volunteers
- 445 people
- Sponsor
- University of Colorado, Denver
End Stage Kidney Disease
The Reducing Adverse Outcomes in Dialysis by Adjusting the pRescription for Dialysate Potassium Trial
This will be a randomized controlled pilot trial comparing usual care to a precision approach to dialysis potassium prescribing.
- Trial name
- RADAR-K (NCT07051447)
- Testing
- PKRxHD, Dialysis
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
End of Life Care, Liver Cirrhosis
Palliative Care for Patients With Liver Cirrhosis
Background: Patients with liver cirrhosis rarely receive palliative care although the Danish Health Authorities and WHO recommend it.
- Conditions
- End of Life Care, Liver Cirrhosis, Nurse-Patient Relations, Quality of Life
- Trial name
- LiverCare (NCT05431946)
- Testing
- Advance Care Planning and the consequent actions
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Advanced Cancer, Cancer
Better Real-time Information on Documentation of Goals of Care for Engagement in Serious Illness Communication
The goal of this study is to test the accuracy of Large Language Model-generated serious illness communication (SIC) summaries, the feasibility of delivering the SIC summaries, and to collect perspectives on the SIC summaries…
- Conditions
- Advanced Cancer, Cancer, End of Life
- Trial name
- BRIDGE-SIC (NCT07147023)
- Testing
- LLM SIC Summary Email
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Dana-Farber Cancer Institute
Decision Making, Terminal Illness
Organ Donation and End-of-life Decisions
Variation in organ donation after brain death (DBD) per million population varies markedly between countries, within country regions, between and within intensive care units (ICU).
- Conditions
- Decision Making, Terminal Illness, Tissue and Organ Procurement
- Trial name
- NCT04131140
- Where
- Sweden
- Volunteers
- 12,072 people
- Sponsor
- Swedish Intensive Care Registry
Artificial Intelligence (AI), Dementia
AI-Driven Personalization of End-of-Life Care for the Elderly
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-based software in personalizing high-quality end-of-life care for elderly patients.
- Conditions
- Artificial Intelligence (AI), Dementia, Palliative Care
- Trial name
- PEACE-AI (NCT07027618)
- Testing
- AI-based Software for Personalized End-of-Life Care
- Volunteers
- 140 people
- Sponsor
- Baqiyatallah Medical Sciences University
Type 2 Diabetes Mellitus, DM Nephropathy
Effects of Disease Management on Development of End Stage Renal Disease in Type 2 Diabetic Patients With Nephropathy
Disease management using a multidisciplinary team to achieve and maintain optimal metabolic and cardiovascular risk factors control in Type 2 diabetic patients with nephropathy reduces the incidence of end stage renal disease…
- Trial name
- NCT00309127
- Testing
- Multidisciplinary team care
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Chinese University of Hong Kong
End-Stage Renal Disease, Type 2 Diabetes
Study to Determine the Efficacy of Real-time CGM in Preventing Hypoglycemia Among Insulin-treated Patients With DM2 on Hemodialysis, Compared to Standard of Care (POC BG)
The study is conducted to assess the efficacy of real-time CGM data in preventing hypoglycemia in patients with type 2 diabetes and end-stage kidney disease (ESKD), treated with insulin therapy and receiving hemodialysis.
- Trial name
- NCT04473430
- Testing
- Dexcom Real-time G6 Continuous Glucose Monitoring System (CGM), POC Glucose Testing
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Emory University
Cardiovascular Diseases, Cardiovascular Abnormalities
Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)
The primary objective is to assess the effect of 2 dose levels of SNF472 (300 mg and 600 mg) compared to placebo on the progression of coronary artery calcium volume score over a 12-month (52 weeks) period in ESRD patients on HD
- Conditions
- Cardiovascular Diseases, Cardiovascular Abnormalities, Calcifications, Vascular, Endstage Renal Disease
- Trial name
- NCT02966028
- Testing
- SNF472
- Where
- 75 sites in United States, Spain and 1 more
- Volunteers
- 274 people
- Sponsor
- Sanifit Therapeutics S. A.
End-of-life Care
The Effect of End-of-Life Care Awareness Education on Knowledge, Attitudes, and Behaviors of Intensive Care Nurses: A Randomized Controlled Study
This study was designed as a prospective randomized controlled study in order to evaluate the effect of end-of-life care awareness training to be given to intensive care nurses on the knowledge levels, attitudes, and behaviors of…
- Trial name
- NCT05994430
- Testing
- End-of-life care awareness training in intensive care
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Cancer
Evaluation of Multidisciplinary Palliative Care on Terminal Cancer Patients in Taiwan
The purpose of the study is to compare the quality of dying and death of terminal cancer patients from the perspectives of medical staff and main care giver (family). The hypothesis is that their view points will be different.
- Trial name
- NCT01103700
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
End-Stage Kidney Disease, Hemodialysis
Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients
This is a prospective, randomized, double-blind, parallel group trial to assess the efficacy and safety of intravenous dextrose 5% solution compare with normal saline (standard care) in wash back procedure during haemodialysis in…
- Trial name
- NSD5 (NCT02590081)
- Testing
- Dextrose 5%, normal saline
- Where
- 15 sites in Malaysia
- Volunteers
- 434 people
- Sponsor
- Penang Hospital, Malaysia