Clinical trials: Test
Glaucoma, Open-Angle, Ocular Hypertension
Evaluation of Rate of Progression With Perimetry in Newly Diagnosed Open Angle Glaucoma
The purpose of this study is to evaluate rate of progression in newly diagnosed open angle glaucoma with different types of perimetry.
- Trial name
- NCT02379208
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Gonorrhea, Chlamydia
Pay-it-forward Gonorrhea and Chlamydia Testing Among Men in China
PIONEER is a three-arm, programmatic cluster randomized controlled trial (RCT) to compare effectiveness of three implementation strategies, followed by a mixed-methods implementation evaluation study
- Trial name
- NCT05723263
- Testing
- Standard Pay-it-forward, Community Engaged Pay-it-forward, Control arm
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hypertension
Blood Pressure Monitoring in Hypertensive Populations: Device Testing, Feasibility, Acceptability
The goal of this study is to test a novel cuffless blood pressure (BP) monitoring device (BIO-Z) within adults with hypertension (high blood pressure) for clinical use.
- Trial name
- NCT05601414
- Testing
- BIO-Z, Finapres Nova
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Yale University
Breast Cancer, Ovarian Cancer
Methods in Education for Breast Cancer Genetics
In 1997, the Genetics Department of the NCI Medicine Branch helped establish a breast cancer genetics program at the National Naval Medical Center s Breast Care Center.
- Trial name
- NCT00001806
- Testing
- Genetic Education and Counseling
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- National Cancer Institute (NCI)
Food Selection
Climate Impact Label Design and Fast-Food Meal Selection
The primary objective of this study is to test the relative effects of climate-impact menu label designs on the healthfulness of consumers' fast-food meal choices.
- Trial name
- NCT06678178
- Testing
- Control (QR) Labels, Warning High Climate Impact Labels, Traffic Light Labels
- Where
- United States
- Volunteers
- 6,622 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
COVID-19, SARS-CoV-2
Professional's Health in Epidemiological Crisis Covid-19
Introduction: Coronavirus Disease 2019 (COVID-19) has caused a global pandemic. Epidemiological and clinical inter-individual differences, symptomatology, recovery and humoral response against Severe Acute Respiratory Syndrome…
- Trial name
- ProHEpiC-19 (NCT04885478)
- Testing
- Immune response monitoring , blood samples
- Where
- Spain
- Volunteers
- 1,350 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Pancreatic Cancer
Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) and Pancreatic Function Following Surgery
The aim of this study will be to determine whether secretin-enhanced MRCP (S-MRCP) as well as traditional magnetic resonance imaging (MRI) of the pancreas will allow the investigators to quantify the pancreas' ability to secrete…
- Trial name
- NCT01094535
- Testing
- Synthetic Human Secretin
- Where
- United States
- Sponsor
- Columbia University
Parenting, Problem Behavior
Parent Training for Parents of Toddlers Born Very Premature:
The purpose of the study is to test the effects of the ezParent (web-based parent training program) intervention and telephone coaching calls (coach) on parent and child outcomes after 3-, 6-, and 12-months.
- Conditions
- Parenting, Problem Behavior, Premature Birth, Parenting Intervention
- Trial name
- ezParent (NCT05217615)
- Testing
- ezParent, Coaching calls, Active Control
- Where
- 3 sites in United States
- Volunteers
- 452 people
- Sponsor
- Ohio State University
Primary Hyperoxaluria
Primary Hyperoxaluria Mutation Genotyping
This study will help us determine whether certain genetic mutations, more than others, are a cause of more severe disease in Primary Hyperoxaluria.
- Trial name
- NCT00589225
- Testing
- Genetic Analysis
- Where
- United States
- Volunteers
- 902 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Depression - Major Depressive Disorder, Overweight (BMI > 25)
Fasting, Exercise, and Diet to Activate Autophagy in Depression
Depression is a common mental health condition that affects millions of people worldwide and is a leading cause of disability. Although current treatments can be effective, many patients do not fully recover or experience…
- Trial name
- AutoFast (NCT07664540)
- Testing
- Performance test
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Tobacco Cessation
Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness
All patients with serious mental illness are abstinent while in the hospital for a psychiatric admission yet almost all return to smoking after discharge.
- Trial name
- NCT04367506
- Testing
- BecomeAnEX, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Maryland, Baltimore
Recurrent Non-Muscle Invasive Bladder Carcinoma, Stage 0a Bladder Cancer AJCC v8
Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy
This phase III trial compares the effect of adding gemcitabine to intravesical Bacillus Calmette Guerin (BCG) versus intravesical BCG alone in patients with non-muscle invasive bladder cancer that has come back after a period of…
- Conditions
- Recurrent Non-Muscle Invasive Bladder Carcinoma, Stage 0a Bladder Cancer AJCC v8, Stage I Bladder Cancer AJCC v8
- Trial name
- GAIN-BCG (NCT07000084)
- Testing
- BCG Solution, Biopsy of Bladder, Cystoscopy
- Where
- 60 sites in United States
- Volunteers
- 330 people
- Sponsor
- Alliance for Clinical Trials in Oncology
HIV/AIDS, Sexually Transmitted Infections
A Pragmatic Trial to Expand Youth-friendly HIV Self-testing
The current study extends the study team's earlier efforts described in ClinicalTrail ID#: NCT04070287 and NCT03874663. The I-TEST (Innovative Tools to Expand Youth-friendly HIV Self-Testing) study known locally as the 4 Youth by…
- Trial name
- I-TEST (NCT04710784)
- Testing
- Sexual health information, I-TEST branded HIVST package, Follow-up testing and clinic assessments
- Where
- Nigeria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Metastatic Head and Neck Squamous Cell Carcinoma
Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers
This phase II/III compares the standard therapy (chemotherapy plus cetuximab) versus adding bevacizumab to standard chemotherapy, versus combination of just bevacizumab and atezolizumab in treating patients with head and neck…
- Conditions
- Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Hypopharyngeal Squamous Cell Carcinoma, Metastatic Laryngeal Squamous Cell Carcinoma
- Trial name
- NCT05063552
- Testing
- Atezolizumab, Bevacizumab, Biospecimen Collection
- Where
- 172 sites in United States
- Volunteers
- 430 people
- Sponsor
- National Cancer Institute (NCI)
Heart Transplantation
L-arginine Supplementation and Exercise; L-arginine Supplementation and Renal Function
exercise capacities are still altered after heart transplantation partly due to peripheral endothelial dysfunction cyclosporin-induced renal dysfunction may be due to renal endothelial dysfunction and can be reversed in an animal…
- Trial name
- NCT00213915
- Testing
- 12 g of L-arginine glutamate during 6 weeks twice a day
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Allergic Rhinitis
Titrated Quantitative Conjunctival Provocation Test (tqCPT)
The clinical relevance of an allergen-specific sensitization is proven e.g., by allergen challenge tests in clinical routine. Several protocols for different challenge tests such as nasal (NPT), bronchial (BPT) or conjunctival…
- Trial name
- tqCPT (NCT02690740)
- Testing
- (diagnostic) conjunctival provocation test with solution: ALK 100, 1.000, 10.000, 20.000, 50.000 and 100.000 SQ-U/ml
- Volunteers
- 23 people
- Sponsor
- Zentrums für Rhinologie und Allergologie Wiesbaden
Diabetes Mellitus, Depression
The Efficacy of Peer Support Model for Depression Care in Patients With Diabetes Mellitus
Introduction: The prevalence of Diabetes Mellitus (DM) is on the rise the world over. About 30% of DM patients suffer from Depression.
- Trial name
- NCT03055468
- Testing
- Peer support
- Volunteers
- 130 people
- Sponsor
- Makerere University
Sudden Cardiac Death, Implantable Defibrillator User
Implantable Cardioverter Defibrillators - Improving Risk Stratification
Worldwide three million people a year die from sudden cardiac death (SCD). In most cases there is no warning and the heart is stopped by a sudden arrhythmia.
- Conditions
- Sudden Cardiac Death, Implantable Defibrillator User, Myocardial Infarction, Arrhythmias, Cardiac
- Trial name
- ICD-IRS (NCT01944514)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Concussion
Concussion Testing: A Novel Non-invasive Concussion Detection Device
The purpose of this study is to establish and evaluate a distinctive signal for concussion.
- Trial name
- NCT02370914
- Testing
- Nautilus NeuroWaveTM System, SCAT
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
Bipolar Disorder (BD), Bipolar Disorder (BPD)
Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models
This preclinical translational study aims to evaluate a new method of delivering lithium using gold nanoparticles for the treatment of bipolar disorder.
- Trial name
- GLAD (NCT07732933)
- Testing
- Peripheral blood sampling for PBMC isolation
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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