Clinical trials: Test
Urinary Bladder, Overactive
A Study to Test the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
The study is intended to test efficacy, safety and tolerability of two doses of once daily (qd) Mirabegron against placebo to treat patients with symptoms of overactive bladder.
- Trial name
- CAPRICORN (NCT00912964)
- Testing
- Mirabegron
- Where
- 151 sites in United States, Canada and 9 more
- Volunteers
- 2,030 people
- Sponsor
- Astellas Pharma Inc
Cognitive Impairment
PAMNEU - Memory in Neurology
Memory in Neurology project (PAMNEU) aims to map the distribution and severity of cognitive impairment in patients of outpatient neurologic offices across the geographical area of the Czech Republic.
- Trial name
- NCT06154564
- Where
- Czechia
- Volunteers
- 600 people
- Sponsor
- Charles University, Czech Republic
Beta-Thalassemia
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients
Beta-thalassemias are hereditary blood disorders caused by reduced or absent synthesis of hemoglobin beta chains, with variable outcomes ranging from severe anemia to clinically asymptomatic individuals.
- Trial name
- SIRTHALACLIN (NCT03877809)
- Testing
- Sirolimus 0.5 mg
- Where
- 2 sites in Italy
- Volunteers
- 26 people
- Sponsor
- Rare Partners srl Impresa Sociale
COPD, Pulmonary Rehabilitation
Tele-based Resisted Exercise for COPD
The present study aims to investigate the effect of six weeks tele-based resisted exercises on cardiopulmonary function, quality of life, muscle strength and functioanl performance among patients with chronic obstructive…
- Conditions
- COPD, Pulmonary Rehabilitation, Telerehabilitation, Cardiopulmonary Exercise Test
- Trial name
- NCT04870632
- Testing
- Education, Video-based pulmonary rehabilitation, Booklet-based pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Mental Health Services, Personality
Validation of Schema Scale of Mental Health Service
Digital Mental Health Service, MINDLiNG, has developed Schema Scale that identifies individual's personality based on schema theory. The goal of this study is to determine the reliability and validity of the Schema Scale.
- Trial name
- NCT05952063
- Testing
- Digital Psychological Test: Schema Scale
- Where
- South Korea
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- 40FY
Dry Skin
A Capacitance and Transepidermal Water Loss Test to Determine the Ability of Sunscreen to Moisturize Skin
To evaluate the ability of 2 Helioblock SX Cream formulations to moisturize skin using capacitance and transepidermal water loss methodology
- Trial name
- NCT00368563
- Testing
- Helioblock SX
- Where
- United States
- Sponsor
- Loreal USA
PrEP Test and Treat
Evaluation of a Facility-based Test, Treat, and Prevent HIV Program Among Men Who Have Sex With Men and Transgender Women in Thailand
This is a prospective observational cohort study that aims to enroll a total of 2000 Thai MSM and TG at five health facilities in four provinces of Thailand. Each participant will be followed for 18 months.
- Trial name
- PrEP (NCT02369887)
- Where
- Thailand
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Medical Education
Elaboration and Feedback for Clinical Reasoning Training
Clinical reasoning abilities can be enhanced by repeated formative testing with key feature questions. An analysis of wrong answers to key feature questions facilitates the identification of common misconceptions.
- Trial name
- NCT05585892
- Testing
- Elaboration and individual mailed feedback
- Where
- Germany
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Implementing EAS/ESC Guideline Recommendation on Lp(a) Testing in Routine Practice
Impact of Implementation Strategies on Lp(a) Testing in Secondary Care Settings
Lipoprotein(a) [Lp(a)] is recognised as an independent, non-modifiable genetic risk factor for cardiovascular (CV) disease. Current guidelines from the European Society of Cardiology (ESC) and the European Atherosclerosis Society…
- Trial name
- Lp(a)CCELERATE (NCT07508007)
- Where
- Germany
- Volunteers
- 4,500 people
- Sponsor
- Novartis Pharmaceuticals
Exposure
Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing
Background: Researchers are interested in developing a registry protocol to obtain biologic and environmental samples anonymously from adult volunteers for use in laboratory tests and studies.
- Trial name
- NCT01087307
- Where
- United States
- Volunteers
- 5,326 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Healthy
Fed Study of Oxycodone Hydrochloride 30 mg Tablets and Roxicodone™ 30 mg Tablets
The objective of this open-label, randomized, two-period crossover study was to compare the oral bioavailability of a Mallinckrodt test tablet formulation of oxycodone 30 mg to an equivalent oral dose of a commercially available…
- Trial name
- NCT00853736
- Testing
- Roxicodone™ tablet 30 mg, Oxycodone hydrochloride tablet 30 mg
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mallinckrodt
Hepatitis C, Nutritional Status
Effect of Agaricus Blazei (Murrill) ss. Heinemann (Sun Mushroom)
The aim of the study was to verify the influence of Agaricus blazei (Murrill) ss. Heinemann (A. blazei) on the evolution of nutritional state and liver function in hepatitis C patients.
- Conditions
- Hepatitis C, Nutritional Status, Hepatitis, Viral, Human
- Trial name
- NCT00564811
- Testing
- Agaricus blazei (Murrill) ss. Heinemann (sun mushroom)
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Cardiovascular Diseases, Personal Health Records
Mobile Cardiovascular Risk Service Trial
Risk factors for cardiovascular disease are poorly controlled even for patients who frequently visit their physician, leading to large numbers of preventable cardiovascular events such as heart attacks and strokes.
- Conditions
- Cardiovascular Diseases, Personal Health Records, Pharmaceutical Care, Mobile Apps
- Trial name
- mCVRS (NCT03081871)
- Testing
- Pharmacist-led cardiovascular risk service (CVRS), Mobile access to study Personal Health Record, Web access to study Personal Health Record
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Iowa
Foreskin HIV Susceptibility
Effect of Antibiotics on Penile Microbiome and HIV Susceptibility Study in Ugandan Men
This pilot study will assess the impact of four antimicrobial products (3 topical, one systemic) on the foreskin microbiome and HIV susceptibility of foreskin-derived CD4+ T cells.
- Trial name
- NCT03412071
- Testing
- Oral Tinidazole, Topical metronidazole, Topical Clindamycin
- Where
- Uganda
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Volunteers
A Phase I Study Comparing the Safety, Pharmacokinetics and Renal Effects of VRP-034 and Marketed Polymyxin B in Healthy Volunteers
This is a Phase 1, single-center, randomized, double-blind, active-controlled clinical study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and nephrotoxicity attenuation potential of VRP-034 compared with…
- Trial name
- VRP-034 (NCT07502144)
- Testing
- VRP-034 (Polymyxin B 500,000 IU), Commercially available Polymyxin B 500,000 IU (Poly-MxB)
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Venus Remedies Limited
INSOMNIA
A Non-inferiority Study With Two Treatment Arms Eszopiclone 3 mg Versus Zopiclone 7.5 mg - for the Treatment of Insomnia
The primary objective of the study is to determine whether eszopiclone (Eurofarma) is non-inferior to the reference drug zopiclone (Imovane®, Sanofi-Aventis) in the treatment of insomnia.
- Trial name
- Eszo (NCT01100164)
- Testing
- Eszopiclone, Zopiclone
- Where
- Brazil
- Volunteers
- 263 people
- Sponsor
- Eurofarma Laboratorios S.A.
Liver Metastases
Functional Liver After SBRT
In this study, the investigators aim to determine the dose-effect relationship between radiation dose and liver function by performing a hepatobiliary scintigraphy (HEBIS) before and after stereotactic body radiotherapy (SBRT)…
- Trial name
- FAFOR (NCT07033364)
- Testing
- Functional liver imaging using hepatobiliary scintigraphy (HEBIS)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- The Netherlands Cancer Institute
Cancer of Prostate, Insomnia
Feasibility Study Testing a Sleep Intervention in Prostate Cancer Patients With Insomnia
This study of a randomized controlled trial aims to evaluate the feasibility of a 12-week sleep program and the randomized controlled trial research procedure.
- Trial name
- NCT03444532
- Testing
- 12-week aerobic exercise and cognitive-behavioral therapy
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Cancer Society
Cancer of the Prostate
Decision Impact Trial of the ExoDx Prostate (IntelliScore)
The purpose of this research study is to investigate the utility of a validated urine test which predicts the likelihood of high grade prostate cancer on an initial prostate biopsy.
- Trial name
- NCT03235687
- Testing
- ExoDx Prostate (IntelliScore)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Exosome Diagnostics, Inc.
HIV Prevention and Care
Lafiya HIV-status Neutral Study - Protocol
The primary objective of this study is to adapt and evaluate the feasibility of "Lafiya," which means "Wellness" in Hausa, a multilevel intersectional stigma \& discrimination (ISD) and HIV testing intervention, to a…
- Trial name
- NCT06312514
- Testing
- LAFIYA
- Where
- Ghana
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
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