Clinical trials: Test
HIV/AIDS, Hepatitis C
Project I Test: Implementing HIV Testing in Opioid Treatment Programs
This study will test two active evidence-based "practice coaching" (PC) interventions to improve opioid treatment programs' (OTPs') provision and sustained implementation of on-site 1) HIV testing and linkage to care and 2)…
- Conditions
- HIV/AIDS, Hepatitis C, Substance Use Disorders, Opioid-use Disorder
- Trial name
- NCT03135886
- Testing
- Information Control, HIV and HCV Testing Practice Coaching Intervention, HIV Testing Practice Coaching Intervention
- Where
- United States
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Columbia University
Defibrillation Testing - ICD Therapy Optimisation
Trop-Shock DFT-testing Versus None
Implantation of a cardioverter defibrillator (ICD) is the treatment of choice for primary and secondary prevention of sudden cardiac death.
- Trial name
- Trop-Shock (NCT01230086)
- Testing
- ICD Implantation without DFT testing, Upper limit of vulnerability testing, T-wave shock with induction of ventricular fibrillation
- Where
- Germany
- Volunteers
- 195 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Behavior, Health
Promoting Repeated HIV Self-testing Among MSM in Hong Kong
In this longitudinal study, we will firstly construct a cohort of HIV negative MSM, who will be exposed to an online video-based intervention promoting HIV testing in general and real-time HIV self-testing with online counselling…
- Trial name
- NCT04434950
- Testing
- Promoting and implementing repeated HIV self-testing and online real-time counseling
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemia
This phase Ib trial studies the side effects and best dose of navtemadlin when given together with the standard chemotherapy drugs cytarabine and idarubicin in patients with acute myeloid leukemia.
- Trial name
- NCT04190550
- Testing
- Cytarabine, Idarubicin Hydrochloride, Navtemadlin
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Helicobacter Pylori Infection, Helicobacter Gastritis
Daily Four Times or Two Times Usage of PPI and Amoxicillin for the First or Second Line H. Pylori Eradication
The hypothesis and plan of the current study are: 1. One induction phase of high dose PPI before eradication will increase intragastric pH and induce H. pylori into an active replicative status.
- Conditions
- Helicobacter Pylori Infection, Helicobacter Gastritis, Helicobacter-Associated Pyloric Ulcer
- Trial name
- NCT03802318
- Testing
- Rabeprazole
- Where
- Taiwan
- Volunteers
- 530 people
- Sponsor
- Chang Gung Memorial Hospital
Asthma (Diagnosis)
Predictive Factors for a Positive Exercise Bronchial Hyperresponsiveness Test
Exertional dyspnea has a significant impact on a child's daily life. Current guidelines recommend performing an exercise challenge test to confirm or rule out exercise-induced bronchoconstriction (EIB).
- Trial name
- PredEIB (NCT07766460)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Lifestyle Program (Scalable Nutrition and Physical Activity) for the Improvement of Nutrition and Physical Activity in Stage 0-III Breast Cancer Survivors
The purpose of this phase II trial is to identify the most effective dose level (number of classes) of a diet and physical activity lifestyle program based on how well it improves diet and physical activity in stage 0-III breast…
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
- Trial name
- NCT04200482
- Testing
- One Diet and Physical Activity Session, Electronic (e) Health (eHealth) Communication Intervention, Twelve Diet and Physical Activity Group Sessions
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Fred Hutchinson Cancer Center
Colorectal Neoplasm
Ultra-sensitivity Quantitative Fecal Immunochemical Test in Detecting Colorectal Advanced Adenoma and Colorectal Cancer
Early detecting and removing of colorectal advanced adenomas can reduce the incidence of colorectal cancer. Because of the less bleeding of advanced adenomas, sensitivities of the common used quantitative fecal immunochemical…
- Trial name
- NCT04856423
- Testing
- The us-qFIT and colonoscopy with pathological examination
- Where
- 6 sites in China
- Volunteers
- 6,000 people
- Sponsor
- Shandong University
Child Development
Testing of Online Version of QAPS
Early evaluation of prewriting skills is important, as prewriting skills set the stage for later learning of the fine motor and visual motor skills needed for writing.
- Trial name
- NCT05905523
- Testing
- Assessing prewriting skills in children
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Virginia Commonwealth University
HIV Testing, HIV Infections
Near Patient Study of the OraQuick ADVANCE® HIV-1/2 Rapid Antibody Test in Oral Fluid and Fingerstick Whole Blood
Point-of-care (POC) tests for HIV are easy to use, rapid and provide accurate results while the patient is still in-front of a healthcare provider (HCP).
- Trial name
- NCT04810559
- Testing
- OraQuick ADVANCE® HIV-1/2 Rapid Antibody Test
- Where
- 4 sites in Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Colorectal Cancer Screening
Telephone Outreach by Navigators to Improve Repeat Fecal Occult Blood Testing
To conduct a randomised control trial to test the effectiveness of telephone outreach programme to improve the uptake rate of repeat fecal occult blood test in colorectal cancer screening programme.
- Trial name
- NCT03974542
- Testing
- telephone outreach
- Volunteers
- 1,000 people
- Sponsor
- Centre for Health Protection, Hong Kong
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study
This phase I trial studies the side effects and best dose of adavosertib when given together with olaparib in treating patients with solid tumors that have spread to other places in the body (advanced) with selected mutations.
- Conditions
- Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm
- Trial name
- NCT04197713
- Testing
- Adavosertib, Olaparib
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Cancer Institute (NCI)
Diabetic Foot, Diabetes Type 2 With Diabetic Ulcer of Toe, Skin Breakdown
CGM and DFU Healing Post-discharge
The purpose of this study is to look at the benefits of using a Continuous Glucose Monitoring (CGM) system compared with standard-of-care testing for patients with type 2 diabetes and diabetic foot ulcers (DFU) and how this will…
- Trial name
- NCT06054659
- Testing
- Real Time Continuous Glucose Monitoring (rt-CGM), Fingerstick blood glucose (FBG) monitoring, Diabetes Education
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- Emory University
Drop Foot
Does Blood Vessel Vasodilation, Caused by Focal Infiltration of Lidocaine Cause Temporary Nerve Functional Recovery for Patients with Common Peroneal Nerve Injury or Entrapment: Testing the 'Phoenix Sign' Effect Between Lidocaine (a Common Local Anesthetic) and Papaverine, a Know Vasodilator
The goal of this clinical trial is to compare lidocaine without epinephrine to papaverine a known vasodilatory agent, in creating improved motor strength in patients with drop foot involving an entrapment of the Common Peroneal…
- Trial name
- NCT06637046
- Testing
- Diagnostic procedures, Lidocaine HCl
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stephen Barrett
Heart Failure with Preserved Ejection Fraction
Study on Heart Failure with Preserved Ejection Fraction with Qishen Granules
With the cardiopulmonary exercise testing as the primary outcome, the study aims to evaluate the efficacy of Qishen Granules on cardiac function, quality of life and biomarker level of patients with heart failure with preserved…
- Trial name
- NCT06377761
- Testing
- Qishen Granules
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Asthma
A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared With CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid
Compare the superiority of CHF 1535 versus CHF 718 in subjects with asthma who are on medium or high dose inhaled corticosteroids.
- Trial name
- FORCE2 (NCT05292586)
- Testing
- Beclomethasone Dipropionate/Formoterol Fumarate, Beclomethasone Dipropionate
- Where
- 91 sites in United States
- Volunteers
- 1,377 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Denture Retention
A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive
The objective of this 4-treatment, 4-period, randomized, crossover, proof of principle bite force study will be to compare bite force measurements over a 12 hour period across two (test) cream denture adhesives, with a currently…
- Trial name
- NCT02937870
- Testing
- Test Product 1, Test Product 2, Reference Product
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Thyroid Cancer, Thyroid Nodule
Molecular Profile of Thyroid Nodules
Profiling and comparative analysis of genomic alterations and miRNA expression in benign and malignant thyroid tumors using histological and cytological specimens will be performed.
- Trial name
- MPTN (NCT05323669)
- Testing
- Molecular testing
- Volunteers
- 400 people
- Sponsor
- Belarusian State Medical University
ADHD, Executive Dysfunction
Virtual Reality (VR) Diagnostic Tool for Attention Deficits/Hyperactivity Disorder (ADHD)
Attention deficit/ hyperactivity disorder (ADHD) is a common neurodevelopmental disorder. The common diagnostic of ADHD is based on psychiatric examination and interview.
- Trial name
- New (NCT04337905)
- Testing
- ADHD-VR diagnosis tool
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tjhin Wiguna
Cystic Fibrosis
Assessment of Cognitive Function and Exercise Capacity in Cystic Fibrosis
No studies in the literature have investigated the simultaneous effects of cognitive function, exercise capacity and arterial stiffness in adult patients with CF.
- Trial name
- NCT06175182
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
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