Clinical trials: Test
Lung Inflammation
Quantifying Airway Inflammation With Radiologic Tests
In this randomized, double-blind, placebo controlled trial we used positron emission tomography to determine if lovastatin or recombinant human activated protein C exhibit anti-inflammatory effects in humans following…
- Trial name
- NCT00741013
- Testing
- Endotoxin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pulmonary Embolism
Non-invasive Diagnosis of Pulmonary Embolism by Use of Biomarkers in Exhaled Breath
In this study, a new, non-invasive method for diagnosis of pulmonary embolism (PE) will be tested. In pre-clinical studies, the investigators have identified 151 putative biomarkers for pulmonary embolism in the exhaled breath…
- Trial name
- NILEX (NCT06135220)
- Testing
- New method for diagnosis of pulmonary embolism (PE) in order to validate/consolidate 151 putative identified biomarkers for PE in the exhaled breath.
- Where
- Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
End-stage Liver Disease (ESLD), Cirrhosis, Liver
RTX001 Autologous Engineered Macrophages for Liver Cirrhosis
The purpose of this study is to assess the safety and efficacy of RTX001 in patients with end-stage liver disease. This study is the first time RTX001, a macrophage cell therapy engineered to have an anti-inflammatory and…
- Conditions
- End-stage Liver Disease (ESLD), Cirrhosis, Liver, Cirrhosis, Decompensated, Liver Diseases
- Trial name
- EMERALD (NCT06823713)
- Testing
- RTX001
- Where
- 15 sites in Spain, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Resolution Therapeutics Limited
Aneurysm
Cognition and Functional Connectivity After Elective Treatment of Brain Aneurysms
The aim of this proposal is to investigate the effects of uneventful microsurgical and endovascular treatment of unruptured saccular non-giant anterior communicating artery [ACoA] aneurysms on resting state functional…
- Trial name
- NCT03140020
- Testing
- Clipping, Coiling
- Where
- 2 sites in Austria
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Stroke
Reliability and Validity of The Figure of 8 Walk Test With and Without Dual-Task
For people with stroke, walking on a curved path is more difficult than walking on a straight path and can lead to falls. Most of the outcome scales assessing the gait of people with stroke involve walking in a straight line or…
- Trial name
- NCT06540482
- Testing
- Reliability test
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Afyonkarahisar Health Sciences University
Infections, Rotavirus
Number of Rotavirus (RV) Related Hospitalizations in Belgium - Season 2010-2011
This study aims to confirm the statistically significant decline in rotavirus related and in acute gastro-enteritis (AGE) related hospital admissions that was observed in 11 participating hospitals, after the introduction of RV…
- Trial name
- NCT01563159
- Testing
- Data collection
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
HIV
HIV Test and Treat to Prevent HIV Transmission Among MSM and Transgender Women
This study will recruit men and transgender women with acute or recent HIV infection. It wil look at how HIV medicines (ART) when given very early after HIV infection affect the amount of HIV in the blood, semen and rectal…
- Trial name
- SABES? (NCT01815580)
- Testing
- Atripla or Stribild
- Where
- Peru
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
SARS-Cov-2, Covid19
Clinical Evaluation of a Point-of-Care (POC), SARS-CoV-2 (COVID-19) IgG Antibody Test in Fingerstick Whole Blood
Prospective, multi-center, observational, blinded clinical trial to compare a new point of care (POC) SARS-CoV-2 IgG antibody test to a reference SARS-CoV-2 PCR test using fingerstick whole blood.
- Trial name
- NCT04699903
- Testing
- POC SARS-Cov-2 IgG Antibody test
- Where
- 3 sites in United States
- Volunteers
- 201 people
- Sponsor
- Lumos Diagnostics
Kidney Transplant Recipients
Non Invasive Blood Test To Diagnose Acute Rejection After Kidney Transplantation
This is a prospective, multicenter, observational study of kidney transplant subjects where blood specimens, intended for dd-cfDNA and other future research purposes, will be drawn after transplant
- Trial name
- DART (NCT02424227)
- Where
- 14 sites in United States
- Volunteers
- 401 people
- Sponsor
- CareDx
Depression, Anxiety Disorders
Tailored Internet-delivered Cognitive Behaviour Therapy for Symptoms of Depression and Comorbid Problems
The overall aim of this study is to develop and test a tailored Internet-delivered psychological treatment for patients with mild to moderate major depression and comorbid anxiety symptoms and compare its efficacy to a…
- Trial name
- TAYLOR1 (NCT01181583)
- Testing
- Tailored Internet-delivered CBT, Non-tailored Internet-delivered CBT, Online discussion group
- Where
- Sweden
- Volunteers
- 121 people
- Sponsor
- Linkoeping University
Coronary Artery Disease
Strain-Encoded Cardiac Magnetic Resonance Imaging for Dobutamine Stress Testing
The purpose of this study is to compare the diagnostic value of SENC to that provided by conventional wall motion analysis for the detection of inducible ischemia during DS-MRI.High-dose dobutamine stress magnetic resonance…
- Trial name
- NCT00758654
- Where
- Germany
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Smoking Cessation, Acceptability of Health Care
Re-Connect Application for Smoking Cessation
This series of studies will explore the acceptability, feasibility, and preliminary efficacy of making access to smartphone applications contingent on objective evidence of smoking abstinence.
- Conditions
- Smoking Cessation, Acceptability of Health Care, Nicotine Dependence, Cigarettes
- Trial name
- NCT05224154
- Testing
- Abstinent Contingent (AC) Re-Connect
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rowan University
Long QT Syndrome Type 1 or 2
Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients
The aim of the study is to evaluate the best stress exam to unmask long QT in patient with KCNQ1 or KCNH2 mutation without long QT interval in rest electrocardiogram.
- Trial name
- QT long (NCT01745666)
- Testing
- exercise test, Epinephrine test
- Where
- 8 sites in France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Behavior, Child, Dentist-Patient Relations
Preparation Protocol for the First Pediatric Dental Visit
To date, not enough attention has been paid to the role of communication before the first dental visit to encourage the child's cooperation and avoid dysfunctional behaviors.
- Trial name
- PREP (NCT05608720)
- Testing
- Information Booklet
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Acute Respiratory Distress Syndrome
Fluid Responsiveness Prediction During Prone Position
Predicting fluid responsiveness is primordial when caring for patients with circulatory shock as it allows correction of preload-dependent low cardiac output states, while preserving patients of the deleterious effects of…
- Trial name
- PROLOAD (NCT05898269)
- Testing
- Trendelenburg maneuver, End-expiratory occlusion test (EE OCC), End-expiratory and end-inspiratory occlusion test (EI OCC)
- Where
- 4 sites in France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Joint Pain
Move Study in Healthy Aging People
Bone and muscle losses occur during ageing leading to increased risk of osteoporosis (there are more than 200 million people affected by osteoporosis worldwide), sarcopenia, loss of functionality and mobility.
- Trial name
- NCT02276183
- Testing
- Nutrition intervention, test formula, progressive physical activity
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy
A Study in Healthy People to Test How 3 Different Formulations of BI 764198 Are Taken up in the Body and How This is Influenced by Food
This trial aims to investigate the relative bioavailability of three different oral formulations of BI 764198 and how this is influenced by food.
- Trial name
- NCT06955754
- Testing
- BI 764198, formulation 1, BI 764198, formulation 2, BI 764198, formulation 3
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Gastrointestinal Dysfunction
Gastric Emptying Validation Pilot Study (MRI Val)
The primary aim of this study is to assess (in healthy volunteers) the rate at which a glucose drink leaves the stomach by sequential magnetic resonance imaging (MRI) of the stomach contents using a 0.5 tesla upright MRI scanner…
- Trial name
- MRIVal (NCT05765123)
- Testing
- Oral glucose tolerance test
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Fallopian Tube Endometrioid Tumor, Fallopian Tube High Grade Serous Adenocarcinoma
Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer
This phase II trial studies how well olaparib with or without tremelimumab works in treating patients with ovarian, fallopian tube, or peritoneal cancer that has come back (recurrent).
- Conditions
- Fallopian Tube Endometrioid Tumor, Fallopian Tube High Grade Serous Adenocarcinoma, Malignant Ovarian Endometrioid Tumor, Ovarian High Grade Serous Adenocarcinoma
- Trial name
- NCT04034927
- Testing
- Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging
- Where
- 20 sites in United States
- Volunteers
- 61 people
- Sponsor
- National Cancer Institute (NCI)
Congenital Heart Disease
Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery
Neonates, children with single ventricle congenital heart disease, and those undergoing multiple complex cardiac surgeries are at high risk of increased perioperative blood loss, and blood product transfusions.
- Trial name
- NCT02410473
- Testing
- Discarded blood samples, Discarded Urine Sample
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.