Clinical trials: Test
Left Ventricular Assist Device
Exercise Tolerance in Patients With Implanted Left Ventricular Assist Device
To evaluate the concept of dynamic pump speed optimization based on the echocardiographic assessment of aortic valve opening during cardiopulmonary exercise test.
- Trial name
- NCT05063006
- Testing
- Cardiopulmonary exercise tests with maintained baseline optimal pump speed settings., Cardiopulmonary exercise test with gradually increased pump speed depending on live echocardiographic imaging.
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Karol Wierzbicki
Diagnostic Tests
25010 - ABL90 FLEX PLUS - Precision Capillary Adult - Clinical Study Protocol
Conducting the ABL90 FLEX PLUS Clinical Precision Study for 15 Parameters in Adult Whole Blood is to validate performance claims for precision in heparinized whole blood for 15 parameters: pH, pCO2, pO2, cCa2+, cCl-, cK+, cNa+…
- Trial name
- NCT07307352
- Testing
- ABL90 FLEX PLUS analyser running SW3.5 MR2.
- Where
- 2 sites in Denmark
- Volunteers
- 39 people
- Sponsor
- Radiometer Medical ApS
Anorexia in Adolescence, Anorexia in Children
Family Functioning and Adverse Side Effects of Family-based Therapy for Anorexia Nervosa
The study examines potential adverse side effects on family functioning and parent-child relationships of standard treatment family-based therapy (FBT) for anorexia nervosa (AN) in children and youths.
- Conditions
- Anorexia in Adolescence, Anorexia in Children, Family Relations
- Trial name
- Spor3 (NCT06097247)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
HIV Infections
Testing a Barbershop-based HIV Prevention Initiative Among Men
To test community-based approaches to engage heterosexual men at risk for HIV and specifically to assess the feasibility and acceptability of a barbershop based HIV prevention program.
- Trial name
- TRIM (NCT06148584)
- Testing
- General, status-neutral HIV education, HIV self-test kits, Information about where to receive HIV prevention services
- Where
- Uganda
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Chronic Myeloid Leukemia
Safety and Feasibility of the Use of Natural Killer Cells in Patients With Chronic Myeloid Leukemia
The purpose of this study is to evaluate safety, feasibility and maximum tolerated dose of NK cells cultured in vitro as adjuvant treatment of patients with chronic myeloid leukemia candidates to allogenic bone marrow…
- Trial name
- NCT03348033
- Testing
- Chronic Myeloid Leukemia + NK cell
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
H. Pylori Infection
ARJ C13 Urea Breath Test System
An open-label, comparative group study to evaluate the equivalency of the PyloPlus 13C Urea Breath Test to predicate devices on the market.
- Trial name
- NCT04036838
- Testing
- PyloPlus UBT System, Histology, Rapid Urease Test
- Where
- 6 sites in United States
- Volunteers
- 415 people
- Sponsor
- ARJ Medical, Inc.
Infectious Diseases, Emerging
Development of a Rapid Diagnostic Test to Identify Crimean-Congo Hemorrhagic Fever - Research and Development Testing
Background Crimean-Congo Haemorrhagic Fever (CCHF) is a rare disease with a death rate between 10% and 50%, rising to 80% during outbreaks.
- Trial name
- DETECT-R&D (NCT06894758)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
HIV Infections
Clinical Performance of Reveal G4 Rapid HIV-1 Antibody Test
To determine the efficacy of an improved rapid diagnostic test using venous whole blood and fingerstick whole blood. The clinical performance of Reveal G4 Rapid HIV-1 Antibody Test will be determined by comparing the results with…
- Trial name
- NCT02190578
- Testing
- Reveal G4
- Where
- 4 sites in United States
- Volunteers
- 1,649 people, healthy volunteers welcome
- Sponsor
- MedMira Laboratories Inc.
Opioid Use Disorder
Towards Testing the Effectiveness of Recovery Community Centers (RCCs)
The goal of this pilot randomized clinical trial is to prepare for a larger randomized clinical trial (RCT) and collect some early data to learn if the intervention can help people who use medications for opioid use disorder…
- Trial name
- NCT07010978
- Testing
- Recovery Community Center Participation, Enhance Treatment as Usual
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Massachusetts General Hospital
Sexually Transmitted Diseases
Clinical Evaluation of Visby Medical Men's Sexual Health Test
This is a multi-center study in which the performance of the Visby Medical Men's Sexual Health Test is evaluated when run by male subjects of 14 years of age and older on self-collected first catch urine samples using the…
- Trial name
- NCT07659808
- Testing
- Visby Medical Men's STI PCR Test Kit
- Where
- 5 sites in United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Visby Medical
Cystic Fibrosis
ICM to Evaluate the Activation of p.Phe508del-CFTR by Lumacaftor in Combination With Ivacaftor
The academic investigator - initiated trial will evaluate in a postapproval setting whether, and if yes, to what extent and variability, the treatment with lumacaftor in combination with ivacaftor reverses the p.Phe508del CFTR …
- Trial name
- OrkambiFacts (NCT02807415)
- Testing
- Lumacaftor plus Ivacaftor
- Where
- 3 sites in Germany
- Volunteers
- 104 people
- Sponsor
- Hannover Medical School
Alcohol Use Disorder
Alcohol Use Disorder and Cannabidiol
This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of full spectrum CBD and broad spectrum CBD, compared to a placebo control (PC), to reduce drinking in participants with alcohol use…
- Trial name
- NCT05613608
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Colorado, Denver
Locally Advanced Cervical Carcinoma
Decision Aid for Chemotherapy in Cisplatin-Intolerant Patients With Locally Advanced Cervical Cancer
The goal of this clinical trial is to investigate the utility and effectiveness of a decision aid in cisplatin-intolerant patients with locally advanced cervical cancer. The main questions it aims to answer are: 1.
- Trial name
- CECIL (NCT05701735)
- Testing
- CECIL Patient Decision Aid
- Where
- 3 sites in Philippines
- Volunteers
- 45 people
- Sponsor
- University of Santo Tomas Hospital, Philippines
Prostate Cancer
Long-term Study to Evaluate and Clinical Outcomes in Patients With Favorable Intermediate Risk Localized Prostate Cancer
This is a long-term prospective registry study to determine whether Prolaris testing in patients with favorable intermediate risk prostate cancer influences physician management decisions toward conservative treatment in patients…
- Trial name
- NCT03290508
- Testing
- Prolaris Testing
- Where
- 34 sites in United States
- Volunteers
- 524 people
- Sponsor
- Myriad Genetic Laboratories, Inc.
Wounds and Injuries, Sports Physical Therapy
Previous Injury History and Performance of Male Elite Ice Hockey Players
BACKGROUND: In ice hockey, skating is a combination of speed, power, and balance. OBJECTIVE:The aim of this study is to examine the relationship between previous injury history and on-ice and off-ice performance of elite male ice…
- Trial name
- NCT04415125
- Testing
- Applying on-ice and off-ice performance tests
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Baskent University
Refeeding Syndrome, Malnutrition
Gastrointestinal Hormones and Metabolomic Profiling Following Mixed-Meal Tolerance Tests in Patients at Risk of Refeeding Syndrome
Introduction: Refeeding syndrome (RS) is a life-threatening metabolic complication of nutritional support. Prolonged fasting, frequently observed in malnourished patients referred for percutaneous endoscopic gastrostomy (PEG)…
- Trial name
- NCT07674589
- Where
- Portugal
- Volunteers
- 15 people
- Sponsor
- Hospital Garcia de Orta
Prostate Cancer
PSA TOOL for Prostate Cancer Screening Discussions
The study team created a tool to help identify patients who may benefit from shared decision making in the primary care setting. This tool is a guide to aid in decision making for prostate cancer screening.
- Trial name
- NCT03135444
- Testing
- PSA TOOL, Revised PSA TOOL, Informal Interview
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Liver Fibrosis, Hepatitis C Virus
Magnetic Resonance Elastography for Assessment of Liver Fibrosis (MK-0000-132)(COMPLETED)
This study will assess the repeatability of Magnetic Resonance Elastography (MRE) in both healthy volunteers and Hepatitis C Virus (HCV)-infected patients with fibrosis and lay the groundwork for the validation of MRE as an…
- Trial name
- NCT00896233
- Testing
- MRE
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Respiratory Tract Diseases, Pulmonary Disease, Chronic Obstructive
Feedback Reports and e-Learning in Primary Care Spirometry
Spirometry is a biomedical test to measure lung function in subject who (may) have a chronic respiratory condition. Performing the test requires a certain level of training and experience from the health care professional who…
- Conditions
- Respiratory Tract Diseases, Pulmonary Disease, Chronic Obstructive, Asthma
- Trial name
- FRESCO (NCT00962455)
- Testing
- e-learning & performance feedback, usual practice
- Where
- Netherlands
- Volunteers
- 1,135 people
- Sponsor
- Radboud University Medical Center
Breast Cancer, Locally Advanced Breast Cancer (LABC)
Patient-Derived Organoids to Functionally Characterize Chemotherapy Resistance in Breast Cancer
This prospective observational study aims to functionally characterize chemotherapy resistance in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy.
- Trial name
- BC-PDO (NCT07516626)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
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