Clinical trials: Testicular
Testicular Neoplasms, Spermatic Cord Torsion
Quality of Life Among Testicular Cancer Survivors
Testicular Cancer is the most prevalent malignancy among men between 20 and 34 years of age, with incidence rates rising in western countries including Israel. Cure rate of testicular cancer exceeds 90% with modern treatments.
- Conditions
- Testicular Neoplasms, Spermatic Cord Torsion, Varicocele, Testicular Hydrocele
- Trial name
- NCT02304575
- Testing
- Questionnaires, Hormonal Function measurement
- Where
- Israel
- Volunteers
- 330 people
- Sponsor
- Rabin Medical Center
Male Infertility
Use of Testicular Spermatozoa in Non-azoospermic Patients
Use of testicular spermatozoa in non-azoospermic patients.
- Trial name
- NAZOSPERM (NCT05203211)
- Testing
- Testicular sperm extraction (TESE)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Istituto Clinico Humanitas
Cancer
Chemotherapy Plus Radiation Therapy in Treating Patients With Unresectable, Residual, or Recurrent Colorectal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses x-rays to damage tumor cells.
- Trial name
- NCT00003704
- Testing
- capecitabine, radiation therapy
- Where
- 18 sites in United States, Canada
- Volunteers
- 51 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Testicular Cancer, Cardiovascular Diseases
Clinical Characterisation of the Vascular Effects of Cis-platinum Based Chemotherapy in Patients With Testicular Cancer
incidence is increasing1,2. Whilst the prognosis is very good with the vast majority of patients cured with orchidectomy alone, those with high risk stage one non seminomatous germ cell cancer (NSCGT) or metastatic disease (NSCGT…
- Trial name
- VECTOR (NCT03557177)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- NHS Greater Glasgow and Clyde
Cancer
Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00499291
- Testing
- paclitaxel albumin-stabilized nanoparticle formulation, gene expression analysis, laboratory biomarker analysis
- Sponsor
- Eastern Cooperative Oncology Group
Thyroid Neoplasms
Testicular Function After Iodine 131 Therapy in Papillary Carcinoma Patients
Papillary cancer may affect patients of any age,with a good prognosis. Most of young patients may hence procreate as often as the general population.131iodine is an essential tool during treatment of thyroid cancer.
- Trial name
- SAPIRA (NCT01150318)
- Testing
- Administration of 131 iodine
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Testicular Positioning Anomalies, Cryptorchidism
Learning to Palpate the Child's Testicles Using Simulation
Hypothesis is that better training of medical students in the examination of boy's external genitalia could improve the diagnosis of testicular position anomalies.
- Trial name
- PaTenSim (NCT07106502)
- Testing
- testicular palpation training on a mannequin
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cutaneous B-cell Non-Hodgkin Lymphoma, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Oblimersen Sodium and Rituximab in Treating Patients With Recurrent B-cell Non-Hodgkin Lymphoma
The goal of this clinical research study is to learn if the combination of oblimersen sodium and rituximab can help to shrink or slow the growth of the tumor in patients with B-cell non-Hodgkin's lymphoma who have not responded…
- Conditions
- Cutaneous B-cell Non-Hodgkin Lymphoma, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma
- Trial name
- NCT00054639
- Testing
- oblimersen sodium, rituximab, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Cancer Institute (NCI)
Testicular Neoplasms, Neoplasms, Germ Cell and Embryonal
Avelumab in Refractory Testicular Germ Cell Cancer.
This is a proof-of-concept study to define efficacy of AVELUMAB in patients with multiple relapsed/refractory germ cell tumors (GCTs).
- Conditions
- Testicular Neoplasms, Neoplasms, Germ Cell and Embryonal, Neoplasms, Testicular Diseases
- Trial name
- NCT03403777
- Testing
- Avelumab
- Where
- Slovakia
- Volunteers
- 8 people
- Sponsor
- National Cancer Institute, Slovakia
Urachal Cancer, Parathyroid Carcinoma
Agnostic Therapy in Rare Solid Tumors
The ANTARES study is a phase II basket trial designed to evaluate the tissue-agnostic efficacy of the monoclonal anti-PD1 antibody, nivolumab, in patients with advanced or metastatic rare tumors.
- Conditions
- Urachal Cancer, Parathyroid Carcinoma, Fibrolamellar Carcinoma, Angiosarcoma
- Trial name
- ANTARES (NCT06638931)
- Testing
- Nivolumab
- Where
- 5 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Male Infertility
Spermatozoa Morphology Selection by Thermotaxis
This study aims to eventually assess the usefulness of thermotaxis for sperm selection in routine clinical practice.
- Trial name
- NCT04849156
- Testing
- Sperm selection by thermotaxis
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Hydrocele, Hydrocele of Tunica Vaginalis
Risk of Scrotal Hydroceles After Nephrectomy For Kidney Cancer
This population-based study will use provincial health administrative data to examine the risk of hospital admission for hydrocelectomy among males who underwent nephrectomy for kidney cancer, compared with males from the general…
- Conditions
- Hydrocele, Hydrocele of Tunica Vaginalis, Hydrocelectomy, Nephrectomy
- Trial name
- NCT07527637
- Testing
- Laparoscopic nephrectomy for kidney cancer, Open nephrectomy for kidney cancer
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Infertility
Chromosomal and Morphological Structure of Mature and Immature Male Germ Cells and Recognition of IL-18 in Testicular Tissue of Azoospermic Men
To develop a biotechnological assay which will be able to recognize germ cells of the spermatogenic lineand and to identify the chromosomal and morphological structure of mature and immature male germ cells, in cases of of sperm…
- Trial name
- NCT00544089
- Where
- Israel
- Volunteers
- 25,907 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Adult Nasal Type Extranodal NK/T-cell Lymphoma, AIDS-related Diffuse Large Cell Lymphoma
Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma
This clinical trial studies genetically modified peripheral blood stem cell transplant in treating patients with HIV-associated non-Hodgkin or Hodgkin lymphoma.
- Conditions
- Adult Nasal Type Extranodal NK/T-cell Lymphoma, AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma, AIDS-related Diffuse Small Cleaved Cell Lymphoma
- Trial name
- NCT01769911
- Testing
- carmustine, cytarabine, melphalan
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Testicular Cancer
Patient Reported Experiences With Sparing External Oblique Fascia Vs Standard Inguinal Orchiectomy
The purpose of this study is to evaluate the difference in patient-reported postoperative outcomes between two standard-of-care surgical techniques for radical orchiectomy (inguinal orchiectomy versus external oblique fascia…
- Trial name
- PRESERVE (NCT06828185)
- Testing
- Radical inguinal orchiectomy, Radical external oblique fascia sparing orchiectomy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Loma Linda University
Germ Cell Tumor of Testis
Sentinel Node Identification Using Gamma and Near-Infrared Imaging in TesticulAr MaLignancies
Testicular seminoma is a malignant tumor with a very high probability of cure. Current treatment approaches provide excellent long-term cancer outcomes.
- Trial name
- SIGNAL (NCT07777887)
- Testing
- Standard treatment: orchiectomy followed by drug therapy and, if necessary, retroperitoneal lymphadenectomy, sentinel lymph node mapping using technetium-99m (Tc-99m) and indocyanine green (ICG) with subsequent orchiectomy
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Fear of Cancer Recurrence, Prostate Cancer
Fear of Cancer Recurrence in Genitourinary Cancer
To perform an analysis of independent predictors of fear of cancer recurrence in patients with malignant genitourinary diseases and their impact on quality of life and survival
- Conditions
- Fear of Cancer Recurrence, Prostate Cancer, Renal Cell Cancer, Urothelial Carcinoma
- Trial name
- NCT04535921
- Testing
- FCR7 questionnaire
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Testicular Cancer
Twenty Years' Experience in Retroperitoneal Lymph Node Dissection for Testicular Cancer in a Tertiary Referral Center
The aim of this study is to evaluate the oncologic and functional outcomes of RPLND as primary treatment (stage I and IIA-IIB with negative markers) or of residual masses after chemotherapy (PC-RPLND) in the treatment of patients…
- Trial name
- NCT06806917
- Where
- 2 sites in Italy
- Volunteers
- 65 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Testicular Cancer
Senescence and the Early Ageing Phenotype After Chemotherapy for Testicular Cancer: the SEA-CAT Study
Cisplatin-combination chemotherapy causes inevitably DNA damage by platinum-DNA adduct formation of both tumor cells but also healthy cells.
- Trial name
- NCT04113122
- Testing
- Skin biopsy, Subcutaneous fat biopsy
- Where
- Netherlands
- Volunteers
- 192 people
- Sponsor
- University Medical Center Groningen