Clinical trials: Testicular
Cancer
Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell Transplant
RATIONALE: Methotrexate and glucocorticoid therapy, such as prednisone or methylprednisolone, may be an effective treatment for acute graft-versus-host disease caused by a donor stem cell transplant.
- Trial name
- NCT00357084
- Testing
- methotrexate, methylprednisolone, prednisone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Fred Hutchinson Cancer Center
Adult Nasal Type Extranodal NK/T-cell Lymphoma, AIDS-related Diffuse Large Cell Lymphoma
Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma
This clinical trial studies genetically modified peripheral blood stem cell transplant in treating patients with HIV-associated non-Hodgkin or Hodgkin lymphoma.
- Conditions
- Adult Nasal Type Extranodal NK/T-cell Lymphoma, AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma, AIDS-related Diffuse Small Cleaved Cell Lymphoma
- Trial name
- NCT01769911
- Testing
- carmustine, cytarabine, melphalan
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Germ Cell Tumor, Testicular Cancer
A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy
The purpose of this study is to the 6-month Venous Thromboembolism (VTE)-free rate in participants with advanced germ cell cancer at high risk of VTE who are receiving standard of care cisplatin-based chemotherapy and low-dose…
- Trial name
- ASPIRE (NCT06866964)
- Testing
- Low-dose ASA
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Wake Forest University Health Sciences
Complication, Prosthesis Durability
SEBBIN Silicone Gel-filled Testicular Implants
This study is part of the clinical evaluation of SEBBIN silicone gel-filled testicular implants, included in the technical file of the device.
- Trial name
- NCT04968470
- Where
- 2 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Groupe SEBBIN
Hearing Loss, Metastatic Malignant Germ Cell Tumor
Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors
This phase I trial evaluates whether adding Pedmark to standard of care cisplatin-based chemotherapy reduces drug-induced ear damage (ototoxicity) in men with stage II-III testicular germ cell tumors that have spread from where…
- Conditions
- Hearing Loss, Metastatic Malignant Germ Cell Tumor, Metastatic Malignant Nongerminomatous Germ Cell Tumor, Metastatic Malignant Testicular Non-Seminomatous Germ Cell Tumor
- Trial name
- NCT07218913
- Testing
- Audiometric Test, Cisplatin, Computed Tomography
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- City of Hope Medical Center
Breast Cancer, Colon Cancer
Understanding Patient Perspectives on the Risks of Ionizing Radiation Used for Medical Imaging
Risks from imaging-related radiation exposure have become a popular topic in the media. Because these tests are commonly applied to patients at a cancer center, it is important to understand what patients know, how they feel…
- Conditions
- Breast Cancer, Colon Cancer, Lung Cancer, Neuroblastoma
- Trial name
- NCT01482741
- Testing
- Focus Group Sessions
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Testicular Cancer
A Case-Control Study of Testicular Germ Cell Tumors Among U.S. Military Servicemen
The incidence of testicular germ cell tumors (TGCT) has increased during the twentieth century and is of particular concern as it primarily affects young men. It is the most common cancer among U.S. males ages 25-34.
- Trial name
- NCT00341588
- Where
- United States
- Volunteers
- 2,772 people
- Sponsor
- National Cancer Institute (NCI)
Cancer
A Structured Walking Program or Standard Therapy in Cancer Patients Undergoing a Donor Bone Marrow Transplant
RATIONALE: A walking program may improve the ability to carry out daily activities after donor bone marrow transplant. PURPOSE: This randomized clinical trial is studying a structured walking program to see how well it works…
- Trial name
- NCT00445731
- Testing
- exercise intervention, management of therapy complications, observation
- Volunteers
- 115 people
- Sponsor
- University of Minnesota
Seminoma
THERApy De-escalation for TESTicular Cancer
THERATEST is looking to collect data from 30 patients actively receiving de-escalation treatments or other standard of care treatments in two UK hospitals.
- Trial name
- THERATEST (NCT06309745)
- Testing
- retroperitoneal lymph node dissection, Carboplatin AUC10
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Queen Mary University of London
Hypogonadism, Malignant Testicular Germ Cell Tumor
7 Tesla MRI Neuroimaging in Testicular Cancer Patients With Hypogonadism and on Androgen Replacement Therapy
This study evaluates 7 Tesla (T) magnetic resonance imaging (MRI) in observing changes in the brain (neuroimaging) in testicular cancer patients who have decreased testosterone (hypogonadism) and are on testosterone (androgen)…
- Trial name
- NCT06191575
- Testing
- 7 Tesla Magnetic Resonance Imaging, Biospecimen Collection, Cognitive Assessment
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Southern California
Cancer
Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients
RATIONALE: Palliative care may help patients with advanced cancer live more comfortably. PURPOSE: This randomized clinical trial is studying an early intervention palliative care program to see how well it works compared to a…
- Trial name
- NCT00253383
- Testing
- counseling intervention, educational intervention, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 329 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Testicular Cancer
Taste, Smell and Chemotherapy (TASTY)
Taste and smell abnormalities are common in cancer patients undergoing chemotherapy, with a prevalence ranging from 46% to 77% for taste changes, and 35% to 75% for smell changes.
- Trial name
- TASTY (NCT01641172)
- Testing
- Dexa scan, audiogram, measurement of heart rate variability and baroreflex sensitivity
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Cancer
Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant
RATIONALE: Giving donor natural killer cells to patients who have undergone donor bone marrow transplant may make the transplant work better and keep cancer cells from coming back.
- Trial name
- NCT00569283
- Testing
- therapeutic allogeneic lymphocytes
- Where
- 2 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- Asan Medical Center
Germ Cell Tumor
Everolimus in Refractory Testicular Germ Cell Cancer
Everolimus in refractory testicular germ cell cancer. Everolimus 10 mg /day/ is administered to the patient until progression, unacceptable toxicity, complete response or inability of the subject to comply with study…
- Trial name
- NCT01466231
- Testing
- Everolimus
- Where
- Slovakia
- Volunteers
- 15 people
- Sponsor
- National Cancer Institute, Slovakia
Testicular Torsion and TLR 4 Was Investigated
Testicular Torsion
Background: Testicular torsion is a scrotal emergency that results in impaired blood supply to the testis and ischemia of the testis as a result of the rotation of the spermatic cord around itself.
- Trial name
- NCT05558072
- Testing
- Toll-like receptor 4
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Childhood Soft Tissue Sarcoma, Childhood Liver Cancer
Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of liposomal doxorubicin in treating children who have…
- Conditions
- Childhood Soft Tissue Sarcoma, Childhood Liver Cancer, Bone Cancer, Brain Tumor
- Trial name
- NCT00019630
- Testing
- doxorubicin HCl liposome
- Where
- 2 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma
Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells…
- Conditions
- Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Cutaneous B-cell Non-Hodgkin Lymphoma
- Trial name
- NCT01116154
- Testing
- lenalidomide, vorinostat, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- City of Hope Medical Center
Cancer, Physical Activity
Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
The purpose of this study is to conduct a 6-month pilot randomized trial to determine the feasibility and acceptability of theory-based mobile weight loss interventions for survivors of adolescent and young adult cancer (AYAs).
- Conditions
- Cancer, Physical Activity, Cancer Survivorship, Mental Health
- Trial name
- AYAConnect (NCT06171945)
- Testing
- AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Testicular Positioning Anomalies, Cryptorchidism
Learning to Palpate the Child's Testicles Using Simulation
Hypothesis is that better training of medical students in the examination of boy's external genitalia could improve the diagnosis of testicular position anomalies.
- Trial name
- PaTenSim (NCT07106502)
- Testing
- testicular palpation training on a mannequin
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Testicular Germ Cell Tumor
Positron Emission Tomography in Detecting Testicle Cancer
RATIONALE: Imaging procedures such as positron emission tomography may improve the ability to detect the extent of cancer and allow doctors to plan more effective treatment for patients who have testicle cancer.
- Trial name
- NCT00045045
- Testing
- positron emission tomography, fludeoxyglucose F 18
- Where
- 8 sites in United Kingdom
- Sponsor
- Institute of Cancer Research, United Kingdom