Clinical trials: Testicular
Inguinal Hernia Repair
A Comparison of Testicular Volume and Blood Flow in Patients With Inguinal Hernia, Hydrocele, and Cord Cyst
Here, investigators aimed to evaluate the effect of inguinal operations performed with a modified Ferguson technique upon testicular volume and blood flow.
- Trial name
- IHR (NCT03033381)
- Testing
- Color Doppler Ultrasound
- Volunteers
- 23 people
- Sponsor
- Kocatepe University
Testicular Cancer
WEST-KOaST Study: WES Analysis of Testicular Cancer Patientsand Their First-degree Family Members
The project aims to identify the possible risk factors regarding the onset of the disease and to evaluate genes and gene modifications responsible for the onset od testicular cancer.
- Trial name
- West-KOaSt (NCT06142500)
- Testing
- Analysis of biological samples of saliva from testicular cancer patients and from their first-degree family members
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma
RATIONALE: Giving high doses of chemotherapy drugs, such as busulfan and cyclophosphamide, before a donor bone marrow transplant helps stop the growth of cancer cells.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a)
- Trial name
- NCT01177371
- Testing
- busulfan, cyclophosphamide, allogeneic bone marrow transplantation
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
Non-obstructive Azoospermia
Testicular Sperm Retrieval Rate After Varicocele Ligation in Men With Non Obstructive Azoospermia
A varicocele is an abnormal dilatation and tortuosity of the veins of the spermatic cord. Although varicoceles are common in the general population and are frequently found on routine physical examinations, they represent the…
- Trial name
- NCT07008495
- Testing
- varicocelectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- South Valley University
Testicular Neoplasms
The Platinum Study Comparison Group
The patients enrolled on this new study will serve as an appropriate comparison group consisting of patients with the diagnosis of germ cell testicular cancer who were cured with surgical resection and did not receive…
- Trial name
- NCT02890030
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Lawrence Einhorn
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant
This pilot clinical trial studies mechanical stimulation in preventing bone density loss in patients undergoing donor stem cell transplant.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
- Trial name
- NCT01558778
- Testing
- management of therapy complications, musculoskeletal complications management/prevention
- Sponsor
- Roswell Park Cancer Institute
Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor
Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bone marrow transplantation may allow doctors to give higher doses of chemotherapy and kill more tumor cells.
- Conditions
- Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Head and Neck Cancer, Kidney Cancer
- Trial name
- NCT00002515
- Testing
- filgrastim, carboplatin, thiotepa
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, Reproduction
ProspectiveMaleAYA - Frequency and Prediction of Therapy-induced Testicular Dysfunction in AYA Cancer Survivors
This study describes the ProspectiveMaleAYA cohort, a multicentre, prospective, longitudinal European study designed to investigate the long-term impact of cancer and cancer treatments on reproductive and endocrine health in…
- Conditions
- Cancer, Reproduction, Infertility, Late Effects
- Trial name
- FertiTestAYA (NCT07612943)
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Cancer, Breast Cancer
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
The purpose of this study is to determine the effectiveness of a digital health program called AYA STEPS, which is designed to help adolescent and young adult (AYA) cancer survivors manage symptoms and engage in recommended…
- Conditions
- Cancer, Breast Cancer, Colorectal Cancer, Sarcoma
- Trial name
- AYA STEPS (NCT06371768)
- Testing
- AYA Educational Information, AYA STEPS
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Duke University
Testicular Neoplasms
Risk of Venous Thromboembolism in Patients Receiving First-Line Chemotherapy for Disseminated Germ Cell Tumours
Recent data (Srikanthan and Tran et al. JCO 2014, in press) have demonstrated that the presence of large retroperitoneal lymph node metastases on baseline staging scans (measuring >5cm in axial dimension) are associated with…
- Trial name
- G3 RPLN PBC (NCT04122430)
- Testing
- Review of Health Information
- Where
- Australia
- Volunteers
- 1,135 people, healthy volunteers welcome
- Sponsor
- Walter and Eliza Hall Institute of Medical Research
Gonadal Dysfunction, Gonadal Failure
Fertility Enhancement Through Regenerative Treatment in Ovaries and Testes
This study investigates the safety and efficacy of stem cell or stem cell-derived exosome therapy for gonadal failure, including testicular failure, hypogonadism, ovarian insufficiency, and premature ovarian failure (POF).
- Conditions
- Gonadal Dysfunction, Gonadal Failure, Azoospermia, Testosterone Deficiency
- Trial name
- FERTILE (NCT06841328)
- Testing
- Stem cells
- Where
- United Arab Emirates
- Volunteers
- 60 people
- Sponsor
- Jumeirah American Clinic
Testicular Neoplasms, Germ Cell Tumors
Conventional Dose Versus High Dose Sequential Chemotherapy for Poor Prognosis Germ Cell Tumors
The purpose of this study is to determine whether the use of a sequential high dose chemotherapy is more effective than conventional dose (i.e.
- Trial name
- NCT02161692
- Testing
- Cyclophosphamide, Etoposide, Cisplatin
- Where
- Italy
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Testicular Cancer
High-dose Chemotherapy for Poor-Prognosis Relapsed Germ-Cell Tumors
The goal of this clinical research study is to learn if 2 cycles of high-dose chemotherapy can help to control germ-cell tumors.
- Trial name
- NCT00936936
- Testing
- Gemcitabine, Docetaxel, Melphalan
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- M.D. Anderson Cancer Center
Cryptorchidism
Cryptorchidism: Impact of in Utero Exposure to Xenobiotics With Hormonal Action
We studied prospectively the incidence of cryptorchidism in Nice area. We tightly matched each affected child (n=95) with 2 healthy controls (n=188) and assessed risk factors for cryptorchidism focussing on prenatal exposure…
- Trial name
- NCT00565513
- Testing
- blood test
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
This phase II trial is studying the side effects and best dose of alemtuzumab when given together with fludarabine phosphate and total-body irradiation followed by cyclosporine and mycophenolate mofetil in treating patients who…
- Conditions
- Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Nasal Type Extranodal NK/T-cell Lymphoma
- Trial name
- NCT00118352
- Testing
- alemtuzumab, total-body irradiation, fludarabine phosphate
- Where
- 2 sites in United States, Italy
- Volunteers
- 12 people
- Sponsor
- Fred Hutchinson Cancer Center
Inguinal Surgery
Ibuprofen Compared to Morphine as a Pediatric Postoperative Pain Management Tool Following Inguinal Surgery
Morphine is now the most commonly used opioid in children for pain management even though the safety of morphine use in children is a primary concern for parents as it is perceived to have more associated risks.
- Trial name
- NCT02603848
- Testing
- Ibuprofen, Morphine
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Non Obstructive Azoospermia
Standard IV Cannula Aspiration (SIVCA): A Novel, Efficient and Minimally Invasive Testicular Sperm Aspiration Technique
Study question: Can enough testicular tissue be aspirated for sperm retrieval in non-obstructive azoospermia (NOA), using a wide bore 14-G Standard IV cannula in comparison to micro-TESE? Summary answer: Standard IV cannula…
- Trial name
- NCT05247723
- Testing
- Standard IV Cannula for aspiration of testicular sperm, Micro-TESE
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Cairo University
Testicular Cancer, Testicular Torsion
Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants
To analyze the short and long term postoperative clinical outcome and patient satisfaction of silicone gel-filled testicular implants.
- Conditions
- Testicular Cancer, Testicular Torsion, Gender Dysphoria, Undescended Testes
- Trial name
- NCT05097820
- Testing
- Placement of testicular prosthesis
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Testicular Germ Cell Cancer
Effectiveness of an Individualized Program of Muscular Strength and Endurance Program for Improving Germ Cell Cancer
Background: Patients with testicular germ cell cancer (GCC) have a high cure rate, however impaired muscle function and fatigue are the most common complications among patients with GCC undergoing treatment with chemotherapy.
- Trial name
- EFICATEST (NCT02433197)
- Testing
- Aerobic program
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Malaga
Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma
Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies
This study uses a drug called dasatinib to produce an anti-cancer effect called large granular lymphocyte cellular expansion. Large granular lymphocytes are blood cells known as natural killer cells that remove cancer cells.
- Conditions
- Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Myeloid Leukemia, Multiple Myeloma
- Trial name
- NCT01643603
- Testing
- Dasatinib, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute