Clinical trials: Testosterone Replacement Therapy
Hypoactive Sexual Desire Disorder
Testosterone Patch's Effects on the Cardiovascular System and Libido
The purpose of this study is to examine the effect of the testosterone patch, in addition to hormone replacement therapy (HRT), on blood vessel walls, insulin levels and sexual desire.
- Trial name
- NCT01208038
- Testing
- Intrinsa Transdermal testosterone patch
- Where
- 3 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Imperial College Healthcare NHS Trust
Hypoactive Sexual Desire Disorder
Study of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido
This study is designed to evaluate efficacy and safety of a testosterone patch as treatment for low libido in naturally menopausal women who are taking estrogen or estrogen/progestin therapy.
- Trial name
- NCT00338312
- Testing
- Testosterone Transdermal System
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- Warner Chilcott
Hypogonadism, Erectile Dysfunction
Testosterone for Penile Rehabilitation After Radical Prostatectomy
The purpose of this study is to determine the effectiveness of testosterone replacement therapy (TRT) in men following surgery to remove the prostate in improving erectile function.
- Trial name
- NCT00848497
- Testing
- Testim®, Viagra®
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mohit Khera
Hypogonadotropism
A Dose Ranging Study to Examine TDS-Testosterone 5%
This study is a continuation of previous studies done in healthy volunteers to prove the efficacy of delivering Testosterone, the male hormone, rapidly across intact skin in s series of doses from low to high in men with…
- Trial name
- PARC-T-D (NCT01894308)
- Testing
- Testosterone, Pump Sprayer
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Transdermal Delivery Solutions Corp
Type 2 Diabetes, Hypogonadism
Reandron in Diabetic Men Witn Low Testosterone Level
In men with type 2 diabetes, low testosterone levels have been associated with insulin resistance, truncal obesity and symptoms such as fatigue and erectile dysfunction.
- Trial name
- NCT00613782
- Testing
- Reandron 1000
- Where
- Australia
- Volunteers
- 88 people
- Sponsor
- Austin Health
Metabolic Syndrome, Testicular Cancer
Study of Testosterone vs Placebo in Testicular Cancer Survivors
The overall purpose of the study is to evaluate the effect of 12 months testosterone replacement therapy in testicular cancer survivors with mild Leydig Cell Insufficiency in order to reduce the risk of cardiovascular disease.
- Conditions
- Metabolic Syndrome, Testicular Cancer, Leydig Cell Failure in Adult
- Trial name
- Einstein (NCT02991209)
- Testing
- Testosterone
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Mikkel Bandak
Hypogonadism
Dose Titration Investigation of the Pharmacokinetics of Testosterone Transdermal Systems in Hypogonadal Men
The study will evaluate the pharmacokinetics of testosterone transdermal systems at steady-state in hypogonadal men.
- Trial name
- NCT01104246
- Testing
- Testerone Transdermal System
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Watson Pharmaceuticals
Spinal Cord Injury, Hypogonadism
Testosterone Replacement Therapy in Chronic Spinal Cord Injury
It has long been recognized that co-morbidity associated with multiple metabolic syndrome, such as adverse body composition, insulin resistance and autonomic nervous system impairment, may lead to significant increase in…
- Trial name
- NCT00266864
- Testing
- Testosterone Transdermal System (Androderm 5 mg patch)
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- VA Office of Research and Development
Pregnancy, Smoking Behavior
HISTOLOGICAL RESULTS IN TRANSGENDER INDIVIDUALS ASSIGNED TO FEMALES AT BIRTH UNDERGOING GENDER AFFIRMATION SURGERY AND IN TESTOSTERONE THERAPY
The aim of this study is to report histological results of genital organs removed during gender affirmg surgery in transgender people assigned female at birth (AFAB), to increase the knowledge about the long-term effects of…
- Conditions
- Pregnancy, Smoking Behavior, Testosterone Replacement Therapy, Drugs
- Trial name
- NCT06710496
- Testing
- analysis of medical records
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Healthy, Osteoporosis
Hormone Replacement in Young Women With Premature Ovarian Failure
The human ovary produces male sex hormones (androgen) and female sex hormones (estrogen). Currently, androgen is not included in hormone replacement therapy for women with premature ovarian failure.
- Conditions
- Healthy, Osteoporosis, Premature Ovarian Failure
- Trial name
- NCT00001951
- Testing
- TMTDS
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Obesity, Hypogonadism
Study of the Effect of Testosterone Treatment on Metabolic Parameters and Urinary Symptoms in Bariatric Patients
The primary purpose of the study is to evaluate, in obese and hypogonadal patients eligible for bariatric surgery, the effect of testosterone replacement therapy in improving lower urinary tract symptoms (LUTS) assessed using the…
- Conditions
- Obesity, Hypogonadism, Prostatic Hyperplasia, Insulin Resistance
- Trial name
- NCT02248467
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Florence
Bariatric Surgery Candidate, Male Hypogonadism
Testosterone in Bariatric Patients
Bariatric surgery is an effective method in the treatment of severe obesity and type 2 diabetes mellitus achieving high remission rates.
- Conditions
- Bariatric Surgery Candidate, Male Hypogonadism, Muscle Loss
- Trial name
- NCT03721497
- Testing
- Testosterone Undecanoate
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Hypogonadotrophic Hypogonadism
The Effect of Testosterone Replacement on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Hypogonadotrophic Hypogonadism
The study searched for answers to two questions 1. What is the effect of testosterone replacement therapy on endothelial dysfunction, inflammation and insulin resistance? 2.
- Trial name
- NCT01533129
- Testing
- Testogel 50 mg transdermal gel, Testosterone 250mg injection
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Gulhane School of Medicine
Physical Frailty, Hip Fracture
Exercise and Testosterone Therapy in Elderly Men With Physical Frailty
The primary aim of this study is to determine, in hypogonadal older men with physical frailty, whether exercise training combined with testosterone replacement therapy can improve skeletal muscle strength, and lean mass, to a…
- Conditions
- Physical Frailty, Hip Fracture, Elective Hip Replacement, Hypogonadism
- Trial name
- NCT00345969
- Testing
- Transdermal Testosterone gel (1%), Supervised exercise training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes Mellitus, Obesity
The Effects of Semaglutide vs Testosterone Replacement Therapy on Functional Hypogonadism and Sperm Quality in Men With Type 2 Diabetes Mellitus and Obesity
The goal of this study is to learn whether semaglutide (treatment for type 2 diabetes and obesity) can improve signs and symptoms of hypogonadism in men with type 2 diabetes, obesity and hypogonadism (a condition when levels of…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Functional Hypogonadism
- Trial name
- SEMAT (NCT06489457)
- Testing
- Semaglutide, Testosterone Undecanoate
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University Medical Centre Ljubljana
Hypogonadism, Obesity
Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.
The purpose of this study was to compare the effects of liraglutide and testosterone replacement therapy on features of hypogonadism and weight loss in obese men with persistent features of hypogonadism after unsuccessful…
- Trial name
- NCT03619330
- Testing
- liraglutide, Testosterone
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Hypogonadism
Study of Serum Testosterone Levels in Non-dosed Females After Secondary Exposure
To further characterize the transfer potential of marketed testosterone gel and new 1.62% formulation.
- Trial name
- NCT00998933
- Testing
- Testosterone gel 1.62%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
Hypogonadism, Malignant Urinary System Neoplasm
Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone
This phase I trial investigates the safety of testosterone replacement therapy around the time of major urologic surgery (perioperative) in order to improve quality of life and post-operative outcomes such as decreased length of…
- Conditions
- Hypogonadism, Malignant Urinary System Neoplasm, Urinary System Disorder, Urinary System Neoplasm
- Trial name
- NCT04731376
- Testing
- Best Practice, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Emory University
Delayed Puberty, Male Hypogonadism
Testosterone Undecanoate Replacement Therapy in Boys With Pubertal Delay or Confirmed Hypogonadism
The absence of clinical signs of pubertal maturation, i.e. pubertal delay, is a relatively frequent reason for consultation in boys.
- Trial name
- NCT05541172
- Testing
- Testosterone Undecanoate
- Where
- Argentina
- Volunteers
- 27 people
- Sponsor
- Hospital de Niños R. Gutierrez de Buenos Aires
Mild Cognitive Impairment, Alzheimer's Disease
Hormone and Information Processing Study
The purpose of this study is to examine the effects of testosterone (T) replacement on changes in thinking and memory, as well as mood in older men with mild cognitive impairment (MCI) and low T levels.
- Trial name
- HIP (NCT00539305)
- Testing
- testosterone gel
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Washington