Clinical trials: The Effectiveness of Anesthesia
Sedation and Anesthesia for Adult Colonoscopy Procedures
A Study Evaluating the Efficacy and Safety of HSK3486
A double-blind, randomized, active controlled, multi-center, parallel group study comparing HSK3486 with Propofol, in patients undergoing a colonoscopy.
- Trial name
- NCT03709056
- Testing
- HSK3486, Propofol
- Where
- 8 sites in China
- Volunteers
- 94 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Local Anesthesia
Efficacy and Safety of Lambdalina (Lidocaine Cream) Versus Placebo as an Anesthetic for Laser Hair Removal
Double-blind, randomized, placebo-controlled trial to assess the efficacy of Lambdalina (lidocaine cream) in reducing pain associated with laser hair removal in women.
- Trial name
- NCT01360749
- Testing
- Lambdalina® (Lidocaine 4% cream)
- Where
- 2 sites in Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ISDIN
Reversal of Neuromuscular Blockade
Evaluation of the Clinical Efficacy and Safety of BriTurn Injection or BrisTurn Prefilled Injection
This study evaluate clinical efficacy and safety in adult patients administered BriTurn injection or BrisTurn Prefilled injection for reversal of neuromuscular blockade induced by Rocuronium or Vecuronium.
- Trial name
- NCT06246331
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Induction and Maintenance of General Anesthesia
A Study to Evaluate the Efficacy and Safety of HSK3486 in the Induction of General Anesthesia
This is a multi-center, randomized, single-blind, propofol injectable emulsion parallel-controlled Phase III clinical study. A total of patients undergoing elective surgery are intended to be enrolled and randomly assigned to…
- Trial name
- NCT04511728
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Fluid Responsiveness Predictability, Hemodynamic Monitoring
Comparison of Acoustic Variability Index (AVI) and Pulse Pressure Variation (PPV) for Predicting Fluid Responsiveness in Mechanically Ventilated Patients
The goal of this clinical trial is to learn if a new medical device called ResQ works to predict fluid needs in adults undergoing surgery under general anesthesia.
- Conditions
- Fluid Responsiveness Predictability, Hemodynamic Monitoring, Anesthesia, General
- Trial name
- NCT07516470
- Testing
- Biological Signal Processing Device for Acoustic Variability Index, Patient monitor for pulse pressure variation, Hemodynamic monitor for cardiac Output and stroke volume variation
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- Signal House Co., Ltd.
Anesthesia, General
Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)
The primary purpose of the study is to determine the time-course of recovery to a T4/T1 ratio of 0.9 within 4 minutes after 4.0 mg.kg^-1 Sugammadex is administered at least 15 minutes after the last administration of rocuronium…
- Trial name
- NCT00298831
- Testing
- Sugammadex, Rocuronium
- Volunteers
- 224 people
- Sponsor
- Merck Sharp & Dohme LLC
Sedation
A Dose-ranging Study to Evaluate the Safety and Efficacy of LUSEDRA (Fospropofol Disodium) as an Intravenous Sedative for Diagnostic or Therapeutic Colonoscopy in Adult Special Populations
The purpose of this study is to evaluate the safety and efficacy of LUSEDRA (fospropofol disodium) and to determine whether a dose lower than currently approved can provide effective moderate sedation required to complete…
- Trial name
- NCT01127438
- Testing
- fospropofol disodium Subgroup 1 Lower Dose, fospropofol disodium Subgroup 1 Approved Dose, fospropofol disodium Subgroup 2 Lower Dose
- Where
- 23 sites in United States
- Volunteers
- 153 people
- Sponsor
- Eisai Inc.
Intubation; Difficult
Investigation of the Effectiveness of Sevoflurane Anaesthesia in Difficult to Intubate Egyptian Patients
The purpose of this study was to record the effectiveness of sevoflurane for intubation in Egyptian, non-obstetric, difficult to intubate (DTI) patients undergoing surgery in regards to the rate of intubation success.
- Trial name
- NCT01749631
- Volunteers
- 97 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Anesthesia
A Phase Ⅰb Study of Remimazolam Tosylate in Healthy Volunteers
The purpose of this study is to evaluate the Pharmacokinetics/Pharmacodynamics and safety of Remimazolam Tosylate in healthy volunteers after loading/maintenance dose regimen.
- Trial name
- NCT03444480
- Testing
- Remimazolam Tosylate
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Soft Tissue Anesthesia (Numbness)
Safety and Efficacy Study of NV-101 in Dental Patients
The purpose of this study was: to determine if NV-101 accelerates recovery from numbness compared to placebo to evaluate safety of NV-101
- Trial name
- NCT00154167
- Testing
- NV-101 (phentolamine mesylate solution)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Novalar Pharmaceuticals, Inc.
Nerve Block, Upper Extremity Surgery
Ropiclobet for Regional Anesthesia and Post-Operative Pain Control in Upper Extremity Surgery
This is a national, single-center, single-arm, open-label Phase II clinical trial designed to evaluate the efficacy and safety of Ropiclobet, a fixed-dose injectable solution containing Ropivacaine HCl, Betamethasone Sodium…
- Trial name
- NCT07131657
- Testing
- Ropivacaine + Clonidine + Betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- PHARMAFINA
Local Anesthesia, Intradermal Injections
A Study to Assess the Safety and Efficacy of a Microneedle Device for Local Anesthesia
The purpose of this study is to determine whether the MicronJet microneedle device is effective for inducing rapid and painless local anesthesia prior to insertions of intravenous catheters.
- Trial name
- NCT00539084
- Testing
- MicronJet
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NanoPass Technologies Ltd
Sedation
Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery or Medical Procedure Without Intubation
The purpose of this study is to evaluate the efficacy and the safety of DA-9501 (Dexmedetomidine) in sedation during the surgery or medical procedure without intubation under monitored sedation care.
- Trial name
- NCT01438931
- Testing
- DA-9501
- Where
- 18 sites in Japan
- Volunteers
- 162 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer