Clinical trials: The Effectiveness of Anesthesia
Anesthesia
Minimum Effective Volume of Local Anesthetic Using Ultrasound for Brachial Plexus Block
The purpose of this study is to determine the minimum effective volume of local anesthetic for interscalene brachial plexus block using ultrasound guidance and nerve stimulator guidance.
- Trial name
- NCT01244932
- Testing
- bupivacaine 0.5%
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pain, Postoperative, Anaesthesia
Lumbar Erector Spinae Plane Block for Back Surgery
Title: A prospective randomized double blind trial of the efficacy of a bilateral lumbar erector spinae block on the 24 h morphine consumption after posterior lumbar interbody fusion surgery.
- Conditions
- Pain, Postoperative, Anaesthesia, Surgery, Nerve Block
- Trial name
- LUMBES (NCT03825198)
- Testing
- Erector spinae plane block, Levobupivacaine 0,25%, spine fusion
- Where
- 2 sites in Belgium
- Volunteers
- 80 people
- Sponsor
- Dr M. B. Breebaart
Total Knee Anthroplasty, Regional Anesthesia
The Sacral Erector Spinae Plane Block in Total Knee Arthroplasty
The goal of this observational study is to learn about the analgesic efficacy and postoperative recovery of two locoregional anesthesia combinations in patients > 18 years (ASA I-III), scheduled for unilateral TKA under spinal…
- Trial name
- sacral ESP (NCT07017400)
- Testing
- Local Anesthetic Injection
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- San Giovanni di Dio Hospital
Gastroscopy, Colonoscopy
A Clinical Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride for Sedation/Anesthesia During Gastroscopy/Colonoscopy
A total of 270 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 2:1 with etomidate as the control group.Neither the…
- Trial name
- NCT06858852
- Testing
- ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 6 sites in China
- Volunteers
- 270 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Anesthetic Effectiveness
Testing the Anesthetic Effectiveness of Buffered Articaine Injected Next to a Lower First Molar.
Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to a lower molar, is more effective than a local anesthetic injection…
- Trial name
- NCT01862614
- Testing
- Articaine Hydrochloride + Epinephrine, Buffered Articaine Hydrochloride + Epinephrine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Anesthetic Gas Consumption and Cost-Effectiveness
Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications
The purpose of this study is to test whether or not the use of a low volume ventilator in an anesthesia machine reduces anesthetic costs significantly as compared to other high volume machines.
- Trial name
- NCT04851314
- Testing
- ICU certified ventilator, Non-ICU certified ventilator
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Irvine
Orotracheal Intubation in Infants Requiring General Anaesthesia for Surgery
Comparing the Efficacy of King Vision in Infants
The primary objective of this study is to find out whether the intubation success rates of Kingvision video laryngoscope is better than that of the conventional laryngoscopes in children < 1 year of age?
- Trial name
- NCT03378154
- Testing
- Orotracheal intubation in infants with Macintosh, Orotracheal intubation in infants with King vision
- Where
- India
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Coronary Artery Bypass, Anesthesia, Conduction
Effect of Transversus Thoracic Muscle Plane Block (TTMP) on Analgesia
In this prospective and controlled study, the investigators investigated the effect of transversus thoracic muscle plane block (TTMP) on analgesia in patients who undergo coronary artery bypass graft (CABG) surgery with median…
- Conditions
- Coronary Artery Bypass, Anesthesia, Conduction, Nerve Block, Pain, Postoperative
- Trial name
- NCT06601530
- Testing
- Transversus Thoracic Muscle Plane Block, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul University - Cerrahpasa
Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia
Comparison of the Efficacy of Tidal Volume Breathing and Vital Capacity Breathing During High-flow Nasal Oxygen
The purpose of this study is to compare the preoxygenation efficacy of tidal volume breathing and vital capacity breathing.
- Trial name
- NCT05571982
- Testing
- Tidal volume breathing technique, Vital capacity breathing technique
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
USE OF ARTIFICIAL INTELLIGENCE IN ANESTHESIA, PREOPERATIVE CARDIOLOGY CONSULTATION REQUIREMENT
The Predictability of the Necessity for Cardiology Consultation in Patients Scheduled for Non-Cardiac Surgery Using Artificial Intelligence Models in Preoperative Anesthesia Assessment
Structured Summary Title Predictability of Cardiology Consultation Requirement in Patients Undergoing Non-Cardiac Surgery Using Artificial Intelligence Models Background Preoperative cardiac risk assessment is essential for…
- Trial name
- NCT07395713
- Testing
- Patient scenarios were presented to different AI models (ChatGPT 4.5, ChatGPT 5, Copilot, Deepseek, Grok, Claude, Gemini Flash, Gemini Pro) with and without prompts.
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Bursa City Hospital
Anesthesia
The Efficacy of Pregabalin on the Duration of the Spinal Anesthesia and the Early Postoperative Pain After Total Knee Arthroplasty
the purpose of this study is to evaluate the effectiveness of administration of pregabalin 2 hours preoperatively on the onset and the duration of the spinal anesthesia in total knee arthroplasty and the role of pregabalin in…
- Trial name
- NCT05071118
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Pain
Efficacy of Ametop Cream in Reducing Pain of Local Anesthetic Infiltration
Ametop is a numbing cream used to ease the pain of having blood drawn or an IV inserted. It is safe and virtually none enters the blood stream.
- Trial name
- Ametop (NCT01864213)
- Testing
- Ametop cream
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Efficacy and Safety
Clinical Studies of the Efficacy and Safety of Remimazolam for Anesthesia Induction and Maintenance in Elderly Patients
the investigators are conducting a clinical study on the efficacy and safety of remimazolam for induction and maintenance of anesthesia in elderly patients.
- Trial name
- NCT06690424
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Affiliated Hospital of Nantong University
Elective Reconstructive Surgery Population
The Effect of Healing Touch on Sleep
Healing Touch improves measures of sleep the night prior to surgery, thus improving surgery-related morbidity.
- Trial name
- Sleep7 (NCT01870076)
- Testing
- Healing Touch, Control, Presence
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Arthroscopic Shoulder Surgery
Effects of Technique on the Local Anesthetic Dose Required for Interscalene Brachial Plexus Block
Interscalene brachial plexus block (ISBPB) is a common nerve block given to patients who are undergoing shoulder surgery. This block has a low, but still significant, rate of complications.
- Trial name
- NCT00731146
- Testing
- Ultrasound Minimum Effective Anesthetic Volume, Nerve Stimulator Minimum Effective Anesthetic Volume
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Sedation
Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery or Medical Procedure Without Intubation
The purpose of this study is to evaluate the efficacy and the safety of DA-9501 (Dexmedetomidine) in sedation during the surgery or medical procedure without intubation under monitored sedation care.
- Trial name
- NCT01438931
- Testing
- DA-9501
- Where
- 18 sites in Japan
- Volunteers
- 162 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Mechanical Ventilation Complication, Upper Airway Obstruction
Nasal Mask Ventilation During the Induction of General Anesthesia
Recently, the investigators demonstrated that nasal route ventilation is superior to the nasal-oral combined ventilation in the absence of jaw thrust and chin up maneuvers.
- Trial name
- NCT01651286
- Testing
- nasal mask, full face mask
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Massachusetts General Hospital
Pediatric Regional Anesthesia, Retrolaminar Block
Retrolaminar Plane Block Versus Anterior Quadratus Lumborum Block in Pediatric Urogenital Surgery
Effective control of postoperative pain following pediatric lower urogenital surgery is important for enhancing recovery and reducing opioid requirements.
- Conditions
- Pediatric Regional Anesthesia, Retrolaminar Block, Pediatric Postoperative Pain
- Trial name
- NCT07711496
- Testing
- Anterior Quadratus Lumborum Block, Retrolaminar Block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University - Cerrahpasa
Molar Incisor Hypomineralisation
Intraosseous Anesthesia in MIH-Affected Teeth
Managing MIH-affected teeth is challenging due to inflammation, sensitivity, rapid caries development, and difficulty achieving anesthesia.
- Trial name
- IO-MIH (NCT07457450)
- Testing
- Intraosseous anesthesia., Local infiltration anesthesia
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- University of Zagreb
Knee Arthroscopy
Efficacy of Intravenous Dexamethasone in Prolonging the Duration of Spinal Anesthesia With Chloroprocaine in Knee Arthroscopy
Chloroprocaine is a short-acting local anesthetic that allows rapid recovery and early ambulation but is currently recommended for procedures lasting 40 minutes or less.
- Trial name
- CHLORODEX (NCT07674576)
- Testing
- Sodium Chloride 0.9%, Dexamethasone, Chloroprocaine Injection [Clorotekal]
- Where
- France
- Volunteers
- 60 people
- Sponsor
- CMC Ambroise Paré