Clinical trials: Therapeutic Alliance
Psychedelic Experiences, Therapeutic Alliance
Ketamine Therapy Experiential Education Study
This study investigates the use of low-dose (0.5-0.75 mg/kg; maximum dose of 60 mg regardless of body weight) ketamine hydrochloride injection, USP administered intramuscularly to healthy clinicians as part of an experiential…
- Conditions
- Psychedelic Experiences, Therapeutic Alliance, Psychology, Perceptual
- Trial name
- KTEES1 (NCT05468047)
- Testing
- Ketamine hydrochloride injection
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Integrative Psychiatry Institute
Suicide Attempt, Suicide
ASSIP, Attempted Suicide Short Intervention Program. Two Year Follow-Up Study
Objective Attempted suicide is the main risk factor for repeated suicidal behavior. However, evidence of the effectiveness of follow-up treatments for these patients is limited.
- Conditions
- Suicide Attempt, Suicide, Suicidal Ideation
- Trial name
- ASSIP (NCT02505373)
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Control Group (CG)
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Bern
Mindfulness, Compassion, Empathy, Working Alliance, Patients' Symptomatology, Psychotherapeutic Process
Mindfulness Training for Psychotherapeutic Care
It has been shown that mindfulness-based interventions (MBI) applied to psychotherapists improve their empathy and increase the therapeutic alliance.
- Conditions
- Mindfulness, Compassion, Empathy, Working Alliance, Patients' Symptomatology, Psychotherapeutic Process, Psychotherapist
- Trial name
- EMAP (NCT04680559)
- Testing
- MCBI, Active Comparator
- Where
- Spain
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Chronic Low-back Pain
Influence of Health Determinants on Physical Exercise Therapy With a Neurocognitive Focus on Chronic Low Back Pain
Protocols in which pain neuroscience education is combined with physical exercise have shown recently greater effectiveness in the treatment of low back pain in comparison to protocols based only on one of the two approaches.
- Trial name
- NCT04115670
- Testing
- Group of educational intervention on the neurophysiology of pain and physical exercises, Control group
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació Universitària del Bages
Men, Age Problem
Register of Therapeutical Patients Over 60 Years
Register for the study of the prevalence and burden of diseases, risk factors and outcomes of hospitalizations in older age groups in the countries of Eurasia.
- Conditions
- Men, Age Problem, Therapeutic Alliance
- Trial name
- ASCLEPIUS (NCT04295057)
- Testing
- Non-intervention
- Where
- Russia
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Eurasian Association of Therapists
Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Bone
BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors
This phase Ib trial finds out the best dose, possible benefits and/or side effects of BAY1895344 and copanlisib in treating molecularly selected patients with solid tumors that have spread to other places in the body (advanced).
- Conditions
- Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
- Trial name
- NCT05010096
- Testing
- Copanlisib, Elimusertib
- Sponsor
- M.D. Anderson Cancer Center
Major Depressive Disorder
Supportive and Supportive-Expressive Treatment for Depression
This study will assign patients to two types of psychotherapies in treating people with a major depression disorder, expressive versus supportive techniques, and will examine their ability to benefit from treatment based on their…
- Trial name
- SSETD (NCT02728557)
- Testing
- Supportive-Expressive Therapy, Supportive Therapy
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- University of Haifa
Therapeutic Alliance
Therapeutic Alliance and Treatment Outcome
This study aims to inform scientific understanding of the impact of the therapeutic alliance and the transition from inpatient to outpatient care.
- Trial name
- NCT05366998
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- Privatklinik Hohenegg
Hypertension, Hypertension Complicated
Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD).
- Trial name
- BHEAT (NCT06948838)
- Testing
- RBPM, MII
- Where
- 7 sites in United States
- Volunteers
- 16,895 people
- Sponsor
- Boston Medical Center
Hypertension, Diabetes Mellitus
MA-CEAL Community Health Ambassador Program
This research is being conducted to investigate how to increase primary care health care visits and screenings and treatment for hypertension and diabetes in residents of housing developments in Boston.
- Conditions
- Hypertension, Diabetes Mellitus, Health Care Utilization
- Trial name
- CHANGE (NCT07136402)
- Testing
- Educating participants about healthcare resources, Healthcare appointments, Workshops
- Sponsor
- Boston Medical Center
Depression - Major Depressive Disorder, Anxiety Disorders
AI-Guided CBT for Depression and Anxiety
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-guided cognitive behavioral therapy (CBT) program for the treatment of mild depression and anxiety disorders in adults.
- Trial name
- AI-CBT-DA (NCT07576686)
- Testing
- AI-Guided Cognitive Behavioral Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Aleksandra Stojanovic
Therapeutic Alliance, Empathy
The Influence of the Cultural Formulation Interview on Therapeutic Work Alliance
The increased cultural diversity in client populations in mental healthcare settings led to the addition of the Cultural Formulation Interview (CFI) in the Diagnostic and Statistical Manual for Mental Disorders (DSM-5).
- Trial name
- CFITWA (NCT05788315)
- Testing
- Cultural Formulation Interview
- Where
- Netherlands
- Volunteers
- 164 people
- Sponsor
- Tilburg University
Mitral Regurgitation
Prospective Treatment Algorithm Guiding Repair of Severe Ischemic Mitral Regurgitation
Ischemic mitral regurgitation is a disease where the mitral valve is regurgitant, or leaking, as a result of changes in the muscle of the heart caused by coronary artery disease Ischemic mitral regurgitation, or IMR, is normally…
- Trial name
- NCT03292497
- Testing
- Treatment Algorithm, No Treatment Algorithm
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Polypharmacy
Development & Pilot of the Technology-Enabled Alliance for Medication Therapy Management
The investigators will link community pharmacy and primary care practices via a shared electronic health record to improve medication therapy management for older patients taking complex prescription (Rx) regimens.
- Trial name
- TEAM (NCT04575155)
- Testing
- TEAM Strategy
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Northwestern University
Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant
Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis
To evaluate the efficacy, safety and tolerability of various doses and durations of linezolid plus bedaquiline and pretomanid after 26 weeks of treatment in participants with either pulmonary XDR-TB, pre-XDR-TB, or treatment…
- Conditions
- Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant, Tuberculosis, MDR, Tuberculosis
- Trial name
- ZeNix (NCT03086486)
- Testing
- Pretomanid, Linezolid, Bedaquiline
- Where
- 11 sites in Georgia, Moldova and 2 more
- Volunteers
- 181 people
- Sponsor
- Global Alliance for TB Drug Development
COVID-19
Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients
The primary objective of this study is to evaluate the time to confirmed clinical recovery in participants hospitalized with COVID-19.
- Trial name
- COMMUNITY (NCT04590586)
- Testing
- Standard of care, Apremilast, Lanadelumab
- Where
- 59 sites in United States, Argentina and 6 more
- Volunteers
- 515 people
- Sponsor
- Amgen
Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus
Video-Based Lifestyle Counseling in Adults With Type 2 Diabetes.
This study evaluates the effectiveness of a 3-month video-based lifestyle intervention, focused on promoting healthy lifestyle habits (healthy eating and increased physical activity), on adults with type 2 diabetes mellitus…
- Conditions
- Diabetes Mellitus (Type 2), Glycemic Control for Diabetes Mellitus, Physical Activity, Healthy Eating
- Trial name
- LIDM2 (NCT07557264)
- Testing
- Video-based lifestyle intervention (own physician), Video-based lifestyle intervention (unknown physician)
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Cardenal Herrera University
Mental Disorders
Effectiveness of DECIDE in Patient-Provider Communication, Therapeutic Alliance & Care Continuation
The purpose of this study is to learn more about how patients and healthcare providers interact in order to improve shared decision making.
- Trial name
- PCORI (NCT01947283)
- Testing
- DECIDE-PA, DECIDE-PC
- Where
- 8 sites in United States
- Volunteers
- 481 people
- Sponsor
- Massachusetts General Hospital
Instability, Joint, Shoulder Dislocation
Improvement of Fatigue in Unstable Shoulder Through a Therapeutic Exercise Program in Physiotherapy
Background: Glenohumeral instability is a highly prevalent pathology; however, there is great controversy in its definition. Traditionally, structural problems such as labral injury or bone loss in the glenoid cavity were…
- Conditions
- Instability, Joint, Shoulder Dislocation, Fatigue, Therapeutic Alliance
- Trial name
- NCT05443295
- Testing
- MoveUS Program, Control intervention
- Where
- 2 sites in Spain
- Volunteers
- 108 people
- Sponsor
- University of Malaga
Schizophrenics
Nonverbal Synchrony, Therapeutic Alliance and Treatment Engagement in First Episode Schizophrenia
The quality of the therapeutic intervention in a first psychotic episode is a major challenge for quality and effectiveness of treatment.
- Trial name
- ASMASS (NCT03917355)
- Testing
- Nonverbal synchrony, therapeutic alliance
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Montpellier