Clinical trials: Therapeutic Endoscopy
Urologic Diseases
Aquablation in Benign Prostatic Hyperplasia in Canada
To document the clinical outcome of Aquablation therapy for BPH patient in Canadian cohort.
- Trial name
- NCT05169892
- Testing
- Aquablation
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Can-Am HIFU Inc.
Glaucoma
Cataract Surgery vs Cataract Surgery With ECPL for Treatment of Plateau Iris Configuration or Syndrome
The purpose of this study is to assess and compare the mechanical angle opening in patients with angle closure due to a plateau iris configuration (elevated iris) using phacoemulsification combined with endoscopic cycloplasty…
- Trial name
- NCT02049333
- Testing
- Phacoemulsification, Endoscopic Cycloplasty (ECPL)
- Where
- 2 sites in Canada
- Volunteers
- 26 people
- Sponsor
- Credit Valley EyeCare
Diabetic Gastroparesis, Idiopathic Gastroparesis
G-POEM for Treatment of Refractory Gastroparesis
This study is performed to assess the efficacy and outcomes of Gastric Per Oral Endoscopic Myotomy "G-POEM" in patients presenting with gastroparesis.
- Conditions
- Diabetic Gastroparesis, Idiopathic Gastroparesis, Gastroparesis Postoperative
- Trial name
- NCT02732821
- Testing
- Gastric Per Oral Endoscopic Myotomy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Acute Pancreatitis (AP), Gallstone Pancreatitis
Pentoxifylline Treatment in Acute Pancreatitis (AP)
The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.
- Conditions
- Acute Pancreatitis (AP), Gallstone Pancreatitis, Alcoholic Pancreatitis, Trauma Acute Pancreatitis
- Trial name
- AP (NCT02487225)
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Mayo Clinic
Anastomotic Leak
Endo-Vac-Therapy for Post-Sleeve Gastrectomy Leaks
Endoscopic negative pressure therapy (ENPT) is a safe technique, showing promising results in the treatment of leakages of the upper and lower gastrointestinal tract.
- Trial name
- NCT05189574
- Testing
- Endoscopic negative pressure therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Ruhr University of Bochum
Prostate Cancer Stage I, Bladder Outlet Obstruction
Transurethral Prostate Enucleation in Surveillance Protocol for Low Risk Prostate Cancer
We will compare oncological and functional outcomes of anatomical endoscopic enucleation of the prostate (AEEP) versus continued medical treatment in low-risk prostate cancer patients for whom an active surveillance protocol was…
- Trial name
- NCT05631080
- Testing
- Anatomical Endoscpic enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Obesity
Multi-Center Feasibility Study of Trans-oral Endoscopic Restrictive Implant System (TERIS) for Treatment of Obesity
The Barosense Trans-oral Endoscopic Restrictive Implant System (TERIS) is an investigational system being evaluated for safety The system uses endoscopic guidance to trans-orally implant a restrictive reservoir for food entering…
- Trial name
- NCT00707720
- Testing
- TERIS procedure
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- BaroSense Inc.
GERD
ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)
OBJECTIVES To study the safety and efficacy of Endoscopic Anti Reflux Mucosal Ablation (ARMA) procedure for the treatment of proton pump inhibitor (PPI) dependent gastro-esophageal reflux disease (GERD) DESIGN OF THE Prospective…
- Trial name
- ARMA (NCT04243668)
- Testing
- ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)
- Where
- India
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Diabetes Mellitus, Type 2, Obesity
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
To assess whether holding incretin-based therapy before endoscopy reduces the likelihood of clinically relevant Residual Gastric Volume (RGV).
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Gastroparesis
- Trial name
- NCT06533527
- Testing
- GLP-1 medication
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Colorectal Cancer, Colonic Adenoma
Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation
The diagnostic accuracy and safety of colonoscopy highly depends on the quality of the pre-procedural bowel preparation. A past history of poor bowel preparation is the most important risk factor of inadequate bowel cleansing at…
- Conditions
- Colorectal Cancer, Colonic Adenoma, Bowel Preparation
- Trial name
- NCT04700410
- Testing
- Pure-Vu System
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 44 people
- Sponsor
- Radboud University Medical Center
Lumbar Disc Herniation, Chronic Low Back Pain
PTED Versus Radiofrequency Ablation for Lumbar Disc Herniation
Lumbar disc herniation (LDH) is a common and frequently-occurring disease giving rise to low back pain and (or) leg pain. There are about 1.5 million people with LDH-related pain, accounting for 10% of outpatients each year in…
- Trial name
- PTED (NCT03634046)
- Testing
- Percutaneous transforaminal endoscopic discectomy, Radiofrequency ablation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Pancreatic Adenocarcinoma
Pilot Study of EUS-Guided Radiofrequency and FOLFIRINOX in Advanced Pancreatic Cancer (RadioFAP )
Pancreatic adenocarcinoma (PDAC) constitutes 90% of pancreatic tumors and is projected to become the second leading cause of cancer-related mortality in Europe by 2030.
- Trial name
- RadioFAP (NCT06743386)
- Testing
- Therapeutic procedure combines EUS-Guided Radiofrequency Ablation (RFA)
- Volunteers
- 30 people
- Sponsor
- French Society of Digestive Endoscopy
Liver Cirrhosis, Esophageal and Gastric Varices
The Effects of Early Enteral Nutrition on Endoscopic Therapy of Esophagogastric Varices in Liver Cirrhosis
The purpose of this study was to evaluate the safety of early enteral nutrition on endoscopic therapy of esophagogastric varices in Liver Cirrhosis ,and to assess the impact of different eating times on patients, so as to…
- Trial name
- NCT04823780
- Testing
- nutrient solution
- Where
- China
- Volunteers
- 397 people
- Sponsor
- Qilu Hospital of Shandong University
Patient Satisfaction, Anxiety State
Effect of Binaural Beats on Level of Anxiety and Toleration in Patients Undergoing Upper Gastrointestinal Endoscopy Without Sedation
To investigate the anxiolytic effects of binaural beat-embedded audio in patients undergoing sedation-free upper gastrointestinal endoscopy
- Conditions
- Patient Satisfaction, Anxiety State, Tolerance
- Trial name
- NCT06114524
- Testing
- binaural music
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Solid Cancer, Bronchial Endoscopy
Impact of Interventional Endoscopy on Quality of Life in Patients With Acute Respiratory Distress Due to Tumor Compression or Obstruction of the Lower Respiratory Tract
Bronchoscopic endoscopy has shown its effectiveness and reliability for the treatment (desobstruction or prothesis) of tumor-induced bronchial obstructions, particularly in the first few weeks.
- Conditions
- Solid Cancer, Bronchial Endoscopy, Therapeutic Bronchofiberscopy
- Trial name
- ENDoRA (NCT07051161)
- Testing
- bronchoscope
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Obesity
Endoscopic Sleeve Gastroplasty for Treatment of Obesity
Emerging endoscopic techniques are minimally invasive and can mimic the anatomic alterations achieved by surgical sleeve gastrectomy.
- Trial name
- NCT02231970
- Testing
- Endoscopic sleeve gastroplasty
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Grupo Hospital de Madrid
Obesity
Benefits of Endoscopic Bariatric Procedures
This 12-months long pilot study will include patients undergoing an endoscopic procedure (endoscopic sleeve gastroplasty [ESG] or transoral outlet reduction [TORe]) as clinically indicated, and subsequent follow up clinic visits…
- Trial name
- NCT05514288
- Testing
- Endobariatric procedure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Informed Consent, Patient Education
Digital-Supported Versus Standard Consent for Advanced Therapeutic Endoscopy
This study will evaluate whether a digital-supported informed consent process improves patient understanding before advanced therapeutic endoscopy procedures.
- Conditions
- Informed Consent, Patient Education, Patient Comprehension, Therapeutic Endoscopy
- Trial name
- DIGI-CONSENT (NCT07723105)
- Testing
- Digital-Supported Informed Consent Pathway, Standard Physician-Led Informed Consent
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Unity Health Toronto
Comparison of Short- Term Success Rates of POEM With LHM, Comparison of Long-term Success Rates of POEM With LHM
Comparison of Peroral Endoscopic Myotomy (POEM) With Laparoscopic Heller Myotomy (LHM) for Treatment of Achalasia
For the treatment of Achalasia, LHM has been the only surgical therapy. Recently, an endoscopic approach for this therapy has been developed (peroral endoscopic Myotomy POEM).
- Trial name
- POEM3 (NCT02018705)
- Where
- 5 sites in Denmark, Germany and 2 more
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pain During Colonoscopy
Improving Quality of Colonoscopy Using a 3D-imager
Coloscopy may be a painful procedure for the patient. This is due to a loop-formation of the coloscope. A 3D-real time imager produced by Olympus creates a real-time image of the scope while a traditional fluoroscopy device will…
- Trial name
- NCT00519129
- Testing
- 3D-imager
- Where
- Norway
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF