Clinical trials: Therapeutic Endoscopy
Gastroesophageal Reflux Disease (GERD)
Endoscopic Fundoplication Versus Proton Pump Inhibitors for GERD Treatment
The study objective is to evaluate the relative merits, safety and effectiveness of Transoral Incisionless Fundoplication (TIF) in GERD patients currently treated with daily Proton Pump Inhibitors (PPIs).
- Trial name
- TvP (NCT00857597)
- Testing
- Transoral Incisionless Fundoplication, Proton Pump Inhibitors; active control
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Ureteral Obstruction
Tolerance and Effectiveness of Ureteral Stents MEMOKATH ® 051 in Chronic Strictures of the Ureter
TOTEME offers to treat certain chronic strictures of the ureter with MEMOKATH 051 to assess its effectiveness, tolerance and mean durability during a 3 years follow up period.
- Trial name
- TOTEME (NCT00790686)
- Testing
- Insertion of Memokath 051
- Where
- 4 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Bordeaux
ERCP
A Prospective Study of Treating Duodenal Papillary Sphincter in Different Ways During ERCP
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly performed to remove bile duct stones.Endoscopic sphincterotomy (EST), endoscopic papillary balloon dilation (EPBD), and endoscopic sphincterotomy plus balloon…
- Trial name
- NCT03416205
- Testing
- Erbao electric knife, Three-cavity incision knife, Columnar expansion balloon
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Zhujiang Hospital
Cirrhosis Portal
EUS Guided Portal-systemic Pressure Gradient Measurement to Predict Treatment Response and Outcomes of Varices to Endoscopic Variceal Ligation in Patients With Chronic Hepatitis.
The aim of the current study is to assess if EUS-PPGM could predict the treatment response and outcomes of varices to endoscopic variceal ligation (EVL) in patients with chronic hepatitis.
- Trial name
- NCT05597488
- Testing
- EUS guided portal pressure gradient measurement
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chinese University of Hong Kong
Hypoxia, High Altitude
SJOV vs. HFNO for Hypoxia During Procedural Sedation at High Altitudes
This study aims to compare the effect of the use of supraglottic jet oxygenation and ventilation (SJOV) with high-flow nasal oxygen therapy (HFNO) on reducing the rate of hypoxia during gastrointestinal endoscopic procedures in…
- Trial name
- NCT05474287
- Testing
- SJOV, HFNO
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Drainage, Thyroid Cancer
No Drainage During Transoral Endoscopic Thyroidectomy Vestibular Approach(TOETVA)
This study evaluates the viability and safety of no drainage tube placement during transoral endoscopic thyroidectomy vestibular approach in treatment of patients with papillary thyroid carcinoma.
- Trial name
- NCT04931576
- Testing
- no drainage tube applied
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pilonidal Sinus
Pilonidal Excision Versus Endoscopic Surgery
Compare clinical outcomes of endoscopic pilonidal sinus treatment (EPSiT) with excision treatment with a randomised clinical trial.
- Trial name
- PEVES (NCT03923621)
- Testing
- EPSiT, Excision
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St Helens & Knowsley Teaching Hospitals NHS Trust
Crohn Disease
Evaluation of the Efficacy and Safety of Endoscopic Dilatation and Biological Therapy in Intestinal Stenosis Due to CD
All patients with Crohn\'s disease, already undergoing biological therapy for the treatment of clinically significant intestinal stenosis and/or already undergoing endoscopic balloon dilatation during the period January 2016…
- Trial name
- NCT06603298
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Barretts Esophagus With Dysplasia
The Impact of Adjuvant Liquid Alginate on Endoscopic Ablation Therapy of Complicated Barrett's Esophagus
This study evaluates the addition of an alginate based solution to twice daily proton pump inhibitor therapy (PPI) in patients undergoing ablative therapy for dysplastic Barrett's esophagus.
- Trial name
- NCT03193216
- Testing
- Alginates
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pancreatitis, ERCP Surgery
Cold Water Irrigation Therapy as an Adjunct to Indomethacin for Post-Endoscopic Retrograde Cholangiopancreatography(ERCP) Pancreatitis
This study is designed to learn whether rinsing the papilla with cold water at the end of an ERCP procedure, in addition to standard medicine, can help lower the chance of developing pancreatitis, which is the most common major…
- Trial name
- NCT07330284
- Testing
- Cold water, Warm water
- Where
- United States
- Volunteers
- 950 people
- Sponsor
- University of Kansas Medical Center
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Walled Off Pancreatic Necrosis (WON)
Rad Predictors for WON
This is a retrospective chart review study examining 1) demographic data such as age, sex, etiology of pancreatitis 2) clinical data including radiological characteristics of walled off pancreatic necrosis, walled off necrosis…
- Trial name
- NCT03801070
- Testing
- endoscopic drainage of walled off pancreatic necrosis
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Washington University School of Medicine
Ureteral Stricture
EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures
The main objective of this clinical investigation is to assess the safety and feasibility of the Optilume DCB for treatment of ureteric strictures.
- Trial name
- ENDURE1 (NCT07020520)
- Testing
- Optilume
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Urotronic Inc.
Obesity, Obesity, Morbid
Luso-Cor Stent Compared to Other Endoscopic Techniques for Management of Fistulas and Anastomotic Dehiscences(ES-LCCE-UDFM)
The global prevalence of obesity has prompted an increase in bariatric surgery, which is the only management strategy that provides long-term weight loss and improvement of obesity-related diseases.
- Conditions
- Obesity, Obesity, Morbid, Esophageal Cancer, Esophageal Neoplasms
- Trial name
- ES-LCCE-UDFM (NCT06862479)
- Testing
- Endoscopic management of fistulas with stents or vacum therapy
- Where
- Portugal
- Volunteers
- 180 people
- Sponsor
- Unidade Local de Saúde Santa Maria
Cirrhosis, Variceal Bleeding
EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment
This study is performed to compare the efficacy and safety of EBL alone and EBL combined with propranolol in patients who were previously performed endoscopic variceal treatment.
- Trial name
- NCT00966082
- Testing
- endoscopic band ligation, endoscopic band ligation+Propranolol
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Korea University
Endometrial Cancer
Endoscopic Suture Gastroplasty (ESG) for Treatment of Obese Patients With Endometrial Cancer
Obesity increases the risk of endometrial cancer, with higher Body Mass Index (BMI) leading to a significant increase in both cancer risk and recurrence.
- Trial name
- ESG-ENDO (NCT07397624)
- Where
- 2 sites in Italy
- Volunteers
- 74 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Right-sided Colon Cancer, Right-sided Colon Adenoma
Preoperative Endoscopic Treatment With Fosfomycin and Metronidazole in Patients With Right-sided Colon Cancer and Colon Adenoma (MEFO-trial)
Clinical studies have shown that patients with right-sided colon cancer have reduced progression-free and overall survival compared to patients with left-sided colon cancer.
- Trial name
- MEFO (NCT04312360)
- Testing
- therapeutic endoscopy with metronidazole and fosfomycin disodium
- Where
- 2 sites in Denmark
- Volunteers
- 28 people
- Sponsor
- Zealand University Hospital
Barrett's Esophagus, Barrett's Esophagus With Dysplasia
Lucid BE Biomarkers Study
The goal of this study is to learn more about genetic factors that may predict if patients with Barrett's Esophagus (BE) will respond to endoscopic treatment.
- Conditions
- Barrett's Esophagus, Barrett's Esophagus With Dysplasia, Esophageal Adenocarcinoma (EAC)
- Trial name
- NCT07887568
- Testing
- Tissue
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
Endoscopic Treatment for Local Residual Neoplasia
Endoscopic mucosal resection (EMR) is considered to be a gold standard of therapy of colorectal lateral spreading tumors (LST) without significant risk for lymphatic spread.
- Trial name
- NCT02386618
- Testing
- Standardized endoscopic treatment of local residual neoplasia
- Where
- Czechia
- Volunteers
- 25 people
- Sponsor
- Vitkovice Hospital
Locally Advanced Pancreatic Cancer
Endoscopic Ultrasound-Guided Loco-regional Chemotherapy Injection as Adjuvant Therapy for Locally Advanced Pancreatic Cancer.
this is a randomized controlled trial aims to compare between patients with locally advanced pancreatic cancer treated with EUS-guided injection of gemcitabine in addition to systemic chemotherapy, versus those who treated with…
- Trial name
- NCT07429643
- Testing
- endoscopic ultrasonograhy guided chemptherapy injection
- Volunteers
- 20 people
- Sponsor
- Assiut University