Clinical trials: Therapeutic Endoscopy
Obesity, Over Weight
Endoscopic Suturing of the Gastric Pylorus to Delay Gastric Emptying and Treat Obesity
The purpose of this study is to demonstrate the efficacy and safety of endoscopic suturing of the gastric pylorus to delay gastric emptying and treat obesity.
- Trial name
- NCT02191501
- Testing
- Pyloric restriction
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Northwell Health
Endoscopic Septoplasty
Endoscopic Versus Conventional Septoplasty in Treatment of Deviated Nasal Septum
This study aims to compare the two techniques of relieving nasal obstruction, and its efficacy in the relief of headache, hyposmia and post-nasal drip and nasal synechiae formation and /or other postoperative complications…
- Trial name
- NCT03666130
- Testing
- endoscopic septoplasty
- Volunteers
- 60 people
- Sponsor
- Assiut University
Gastrointestinal Hemorrhage, Gastrointestinal Neoplasms
Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions
This study evaluates the efficacy of the endoscopic hemostatic powder for the treatment of bleeding from malignant lesions of the upper GI tract.
- Trial name
- NCT02820077
- Testing
- Hemospray (Endoscopic treatment with hemostatic powder)
- Volunteers
- 62 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Crohn's Disease
Role of Capsule Endoscopy in the Evaluation of Mucosal Changes During Treatment of Patients With Active Crohn's Disease
The utility of capsule endoscopy in diagnosing small bowel (SB) Crohn's disease has been demonstrated in a number of studies. Mucosal healing is a good predictor of long term remission.
- Trial name
- CHANCE (NCT02193802)
- Testing
- PillCam® COLON 2 and PillCam Crohn's capsules
- Where
- 11 sites in France, Spain
- Volunteers
- 42 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Hepatocellular Carcinoma, Esophagogastric Varices
Efficacy of TACE With Endoscopic Therapy for Unresectable Hepatocellular Carcinoma
The study is aimed to explore the efficacy of transarterial chemoembolization (TACE) combined with endoscopic therapy for unresectable hepatocellular carcinoma (HCC) complicated with esophagogastric varices (EGV) and seek out…
- Trial name
- NCT05017922
- Testing
- transarterial chemoembolization combined with endoscopic therapy
- Where
- China
- Volunteers
- 89 people
- Sponsor
- Qilu Hospital of Shandong University
Pancreatic Cystic Neoplasm
Endoscopic Ultrasound-Guided Chemoablation for the Treatment of Pancreatic Cystic Neoplasms
This phase II trial tests the effect of endoscopic ultrasound (EUS)-guided chemoablation in treating patients with pancreatic cysts.
- Trial name
- ERASE-Chemo (NCT07529483)
- Testing
- Ablation Therapy, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Peptic Ulcer Hemorrhage
Role of Doppler Ultrasound in Severe Peptic Ulcer Hemorrhage
The aim of study is to evaluate whether Doppler ultrasound can accurately identify patients who are at risk of recurrent bleeding, who will require endoscopic therapy, and who will fail endoscopic therapy.
- Trial name
- NCT00164905
- Testing
- Doppler ultrasound probe
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Chinese University of Hong Kong
Pseudocyst Pancreas, Pancreatic Duct Disorder
The Economic Impact of the Pancreatography in the Endoscopic Treatment of Pancreatic Pseudocysts
Pancreatic pseudocysts (PP) present as a complication that occurs in 5-15% of acute pancreatitis and 26-40% of chronic pancreatitis (1-3).
- Trial name
- NCT04494282
- Testing
- Endoscopic retrograde pancreatography
- Volunteers
- 50 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Barrett Esophagus, Esophageal Cancer
Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus
Esophageal cancer is a deadly disease that is becoming increasingly common in the United States. Barrett's esophagus (BE) is a pre-cancerous state that can develop into esophageal cancer, but is highly treatable.
- Trial name
- NCT05056051
- Testing
- WATS-3D tissue sampling prior to forceps biopsies, WATS-3D tissue sampling following forceps biopsies
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Gastroesophageal Reflux Disease
Endoloop Mediated Cardioplication to Treat Gastroesophageal Reflux Disease
Endoscopic full-thickness plication (EFTP) of cardia/fundus has been shown effective in treating GERD patients. However, EFTP requires proprietary equipment that are not available in many countries.
- Trial name
- NCT06153901
- Testing
- endoloop mediated cardioplication (ECLC) procedure
- Volunteers
- 35 people
- Sponsor
- Qilu Hospital of Shandong University
Paroxysmal Atrial Fibrillation
Clinical Study of the CardioFocus Endoscopic Ablation System for the Treatment of Symptomatic AF
The purpose of this study is to determine the safety and effectiveness of the endoscopic ablation system - adaptive contact (EAS-AC) in treated paroxysmal atrial fibrillation (PAF) with pulmonary vein isolation (PVI).
- Trial name
- NCT00958165
- Testing
- CardioFocus EAS-AC
- Where
- 3 sites in Germany
- Volunteers
- 81 people
- Sponsor
- CardioFocus
Papillary Adenoma
Endoscopic Resection of Papillary Adenomas; a Novel Treatment Algorithm to Prevent Recurrence - a Pilot-study (ERASE-pilot)
Recurrence after endoscopic papillectomy is described in up to 33% of the cases (range 12-33%). This leads to re-interventions, a cumulative risk of adverse events, and the need for long-term follow-up.
- Trial name
- ERASE-pilot (NCT05339607)
- Testing
- Thermal ablation of resection margins by STSC and biliary orifice by cystotome.
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cholangiocarcinoma
Comparison of Biliary Stenting Alone vs. Stenting With Photodynamic Therapy (PDT) During ERCP
This study entails retrospective and prospective review of data from a database protocol. Data gathered will be then analyzed for a set amount of patients. In this study, the investigators will compare biliary stenting vs.
- Trial name
- PDT (NCT01439685)
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Crohn Disease
A Comparative Study of MRI, US and CE for Assessing Treatment Response in Known Crohn's Disease
The aim of this study is to evaluate non-invasive imaging techniques for assessing treatment response in known Crohn's disease. 1.
- Trial name
- NCT03435016
- Testing
- Diagnostic work-up
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- Sygehus Lillebaelt
Achalasia
Peroral Endoscopic Myotomy (POEM) for the Treatment of Achalasia
Achalasia is a chronic disease of altered esophageal motility with resulting functional obstruction to the passage of food leading to poor quality of life and significant morbidity.
- Trial name
- POEM (NCT01832779)
- Testing
- Achalasia subjects
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Florida
Lumbar Herniated Disc
Percutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc Herniation
The purpose of this study is to evaluate the effectiveness of two minimal invasive endoscopic discectomy, PTED and MED, for the treatment of symptomatic lumbar disc herniation.
- Trial name
- NCT01997086
- Testing
- Percutaneous transforaminal endoscopic discectomy (PTED), Microendoscopic discectomy (MED)
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Portal Vein Thrombosis, Liver Cirrhosis
TIPS vs Endoscopic Therapy for Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis
portal vein thrombosis may be a negative prognostic marker of variceal bleeding in liver cirrhosis. Compared with conventional endoscopic and pharmacological therapy, transjugular intrahepatic portosystemic shunt may further…
- Trial name
- NCT02485184
- Testing
- Transjugular intrahepatic portosystemic shunt, Non-selective beta blockers, Endoscopic therapy
- Where
- 8 sites in China
- Volunteers
- 120 people
- Sponsor
- Air Force Military Medical University, China
Neuroendocrine Tumor of Pancreas (Disorder), Neuroendocrine Tumor Grade 1
Pancreatic Radiofrequency Under High Echo-endoscopy in the Management of Pancreatic Neuroendocrine Tumors
Pancreatic radiofrequency ablation (RFA) could therefore be an alternative to the monitoring of pancreatic neuroendocrine tumors (PNETs) and more particularly nonfunctioning PNETs (NF-PNETs), which is costly and anxiety-inducing…
- Trial name
- RFANET (NCT04520932)
- Testing
- Radiofrequency ablation
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Institut Paoli-Calmettes
Esophagogastric Varices, Portal Hypertension
Treatment Outcomes for Portal Hypertension Esophageal and Gastric Varices
This study is a single-center, prospective cohort study based on real-world data. Patients with portal hypertension and esophagogastric varices were enrolled and divided into an endoscopic treatment group and a non-endoscopic…
- Trial name
- NCT07358663
- Where
- China
- Volunteers
- 1,384 people
- Sponsor
- Shanghai Zhongshan Hospital
Small Gastric Subepithelial Tumor
Endoscopic Unroofing for Small Gastric SETs
Background: Accurate diagnosis of small gastric subepithelial tumors (SETs) is essential in order to assess their malignant potential.
- Trial name
- NCT02587923
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna