Clinical trials: Therapeutic Endoscopy
Endoscopic Hemostasis, Sedation
Endoscopic Hemostatic and Sedative Treatment of Esophageal and Gastric Variceal Bleeding
Remazolam besylate was used for sedation during endoscopic hemostasis in patients with esophageal and gastric varices rupture and bleeding in liver cirrhosis.
- Trial name
- NCT05554965
- Testing
- Propofol, Remimazolam besylate
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Renmin Hospital of Wuhan University
Endoscopic Submucosal Dissection
Endoscopic Submucosal Dissection for Early GI Neoplasia in the United Kingdom
Multicentre cohort study on the use of endoscopic submucosal dissection for the treatment of early gastrointestinal neoplasia.
- Trial name
- ESDUK (NCT03039309)
- Testing
- Endoscopic Submucosal Dissection
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Obesity and Obesity-related Medical Conditions, Obesity and Overweight
REvision of VSG with Ablation of the Mucosa Procedure
The purpose of this study is to evaluate the feasibility, safety, and tolerability of endoscopic selective gastric mucosal ablation (GMA) using argon plasma coagulation after sleeve gastrectomy.
- Conditions
- Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Obesity Prevention, Obesity Recidivism
- Trial name
- REVAMP (NCT06671119)
- Testing
- Gastric Mucosal Ablation (GMA)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Dr. Christopher McGowan
Thyroid Diseases
The Feasibility and Safety of the TOETVA for Benign Thyroid Nodules
Thyroid surgery has been developed as a new technique for zero scar in surgery by applying transoral endoscopic thyroidectomy with sublingual approach.
- Trial name
- NCT03158961
- Testing
- Transoral endoscopic thyroidectomy vestibular approach
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Hepatocellular Carcinoma, Variceal Bleeding
Prevention of Variceal Rebleeding by EUS-guided vs Conventional Endoscopic Therapy in Hepatocellular Carcinoma Patients
Rebleeding rate is high in hepatocellular carcinoma (HCC) patients with variceal bleeding despite conventional endoscopic therapies for esophageal and gastric varices (EV, GV).
- Trial name
- EUS-SPV (NCT05629845)
- Testing
- endoscopic ultrasound-guided therapy, conventional endoscopic therapy
- Where
- Hong Kong
- Volunteers
- 84 people
- Sponsor
- Chinese University of Hong Kong
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
UK Post-market Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue
A post-market, non-interventional, two-arm, long-term follow-up study of patients previously enrolled in the WATER Study (NCT02505919) - which was a prospective multi-centre randomized blinded study comparing Aquablation of the…
- Trial name
- NCT04658056
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- PROCEPT BioRobotics
Obesity, Morbid, End Stage Renal Disease
Endoscopic Sleeve Gastroplasty With Endomina® for the Treatment of Obesity in Kidney Transplant Candidates
The aim of this pilot prospective interventional study is to evaluate the efficacy of endoscopic sleeve gastroplasty (ESG) in allowing obese subjects (≥35 kg/m2) with end stage renal disease who need of kidney transplantation to…
- Conditions
- Obesity, Morbid, End Stage Renal Disease, Kidney Transplantation, Endoscopic Sleeve Gastroplasty
- Trial name
- ESGiTXKidney (NCT05917795)
- Testing
- Endoscopic Sleeve Gastroplasty (ESG)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Colonic Polyp
Cold Snare Polypectomy Versus. Endoscopic Mucosal Resection
The investigators will investigate the efficacy of EMR compared to CSP in treatment of small colon polp (6~10mm). One aim of this study was to investigate the necessity of EMR on resection of small colon polyp.
- Trial name
- NCT02476747
- Testing
- EMR, CSP
- Where
- South Korea
- Volunteers
- 103 people
- Sponsor
- Asan Medical Center
Hepatocellular Carcinoma
Comparative Study of Carvedilol Monotherapy Versus Combination Therapy With Endoscopic Variceal Ligation (EVL) for Primary Prophylaxis of Variceal Bleeding in Patients With Hepatocellular Carcinoma With High-Risk Esophageal Varices
Esophageal varices are common in patients with hepatocellular carcinoma (HCC), with an incidence rate of 63% at the time of HCC diagnosis.
- Trial name
- NCT06836778
- Testing
- Carvedilol Tablets, Endoscopic Variceal Ligation
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Cecostomy; Complications, Constipation
LAPEC for the Treatment of Severe Constipation
Effective treatment for constipation is a real clinical challenge especially in patients with severe symptoms. Dietary measures (bulking agents) and drugs (laxatives, stool softeners, suppositories and enemas etc.) have limited…
- Trial name
- NCT03909204
- Testing
- LAPEC
- Where
- Slovakia
- Volunteers
- 30 people
- Sponsor
- University Hospital Trnava
Obesity, Adiposity
Endoscopic Gastric Mucosal Ablation as a Primary Obesity Therapy
This study is intended to investigate safety and feasibility of a new weight loss technique called endoscopic Gastric Mucosal Ablation (GMA) that does not require surgery, but can be achieved using an endoscopic procedure.
- Trial name
- COMET (NCT05486338)
- Testing
- Hybrid Argon Plasma Coagulation (HAPC)
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Erbe Elektromedizin GmbH
Achalasia
Anterior Orientation vs Posterior Orientation in Per Oral Endoscopic Myotomy POEM for the Treatment of Achalasia
The purpose of this study is to compare the safety and efficacy of the anterior versus posterior myotomy technique in Per Oral Endoscopic Myotomy (POEM) for the treatment of Achalasia.
- Trial name
- NCT03228758
- Testing
- Per Oral Endoscopic Myotomy
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- NYU Langone Health
Internal Hemorrhoid
Recurrence Rate of Minimally Invasive Endoscopic Treatment of Internal Hemorrhoids
2.1 Main objective: To observe the short-term and long-term recurrence rates of various endoscopic minimally invasive treatment methods for internal hemorrhoids and different time points of endoscopic minimally invasive treatment…
- Trial name
- NCT06250140
- Testing
- Tie up device
- Volunteers
- 900 people
- Sponsor
- Shenzhen Hospital of Southern Medical University
Obesity & Overweight
Gastric On in Obesity Management: Evaluation of the Safety and Efficacy of the 6-Month Gastric Balloon (Prospective)
The goal of this clinical study is to learn whether the GastricOn 6-Month Gastric Balloon helps adults with obesity lose weight, and how safe it is.
- Trial name
- GastricOn (NCT07869758)
- Testing
- GastricOn intragastric balloon
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Rigicon, Inc.
Esophageal and Gastric Varices
Clinical Study on Endoscopic Management of GOV1 Esophagogastric Varices
The patients with GOV1 esophagogastric varices will be treated with gastric variceal tissue gel injection, at the same time, the esophageal varices were treated with ligation, sclerotherapy, or no treatment.
- Trial name
- NCT05978752
- Testing
- Endoscopic gel embolization of gastric fundus varices and ligation of esophageal varices, Endoscopic gel embolization of gastric fundus varices and sclerotherapy of esophageal varices, Endoscopic gelatinous embolization of gastric varices (esophageal varices not treated)
- Volunteers
- 57 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Rhinosinusitis, High-risk Patient
Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy
Justification: Chronic rhinosinusitis (CRS) is one of the most common inflammatory diseases with an incidence and prevalence superior to 10%.
- Trial name
- AZI-CRS (NCT02307825)
- Testing
- Azithromycin
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Zenker Diverticulum
A New Treatment for Zenker's Diverticulum-submucosal Tunneling Endoscopic Septum Division
Zenker's Diverticulum (ZD) is a sac-like outpouching of the lining of the esophageal wall at the upper esophagus. It is a rare disease typically seen in the middle-aged and older adults.
- Trial name
- STESD (NCT03125733)
- Testing
- Submucosal tunneling endoscopic septum division
- Where
- 2 sites in United States, China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Achalasia
Peroral Endoscopic Myotomy (POEM) For The Treatment Of Achalasia: A Registry
Prospective Multicenter registry study to assess the safety and efficacy of clinically indicated peroral endoscopic myotomy (POEM) for the treatment of Achalasia
- Trial name
- POEM Registry (NCT02162589)
- Testing
- POEM
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Pain, Bone Marrow Oedema
TEP Versus Open Repair of Sportsman's Hernia
Sportsman's hernia causes chronic groin pain in physically active adults. Open hernia repair without mesh or laparoscopic technique with mesh have been advocated in the treatment of sportsman's hernia.
- Trial name
- sports hernia (NCT01876342)
- Testing
- open repair, endoscopic TEP repair
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Kuopio University Hospital
Obesity
Bariatric Endoscopy for Treatment of Obesity
A single-center, randomized trial will be conducted in order to compare three Endoscopic Gastroplasty (EG) techniques in obese patients (BMI 30-44.99 kg/m2) at Gastroenterology and Gastrointestinal Endoscopy Unit, Mater Olbia…
- Trial name
- NCT04854317
- Testing
- Endoscopic gastroplasty
- Where
- Italy
- Volunteers
- 189 people
- Sponsor
- Mater Olbia Hospital