Clinical trials: Therapeutic Endoscopy
Gastroparesis
G-POEM vs PEG-J in Gastroparesis Patients
Study design: A randomized non-blinded controlled clinical trial with two study arms (G-POEM and PEG-J). Treatment success is measured using the GCSI at baseline before intervention and six months after intervention with a…
- Trial name
- NCT06372132
- Testing
- G-POEM
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Biliary Tract Injuries
Endoscopic Treatment of Post Surgical Biliary Tract Injury
The objective of this study is to determine the technical and clinical success rate of endoscopic treatment in a population presenting only with iatrogenic injuries of the bile ducts, excluding the cystic duct.
- Trial name
- EpSB (NCT07345936)
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Strasbourg, France
Barrett Syndrome, Barrett's Syndrome
CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia
This study focuses on demonstrating the value of probe-based Confocal Laser Endomicroscopy (pCLE) in guiding endoscopic therapeutic procedures in Barrett's Esophagus (BE).
- Conditions
- Barrett Syndrome, Barrett's Syndrome, Barrett's Esophagus, Barrett Esophagus
- Trial name
- CLEAN-MARGIN (NCT01032044)
- Testing
- Standard endoscopic evaluation, pCLE guided evaluation
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 164 people
- Sponsor
- Mauna Kea Technologies
Schistosomiasis Mansoni, Portal Hypertension
Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery
Upper gastrointestinal bleeding (UGIB) is a major cause of morbidity and mortality in patients with portal hypertension secondary to schistosomiasis mansoni.
- Conditions
- Schistosomiasis Mansoni, Portal Hypertension, Upper Gastrointestinal Bleeding
- Trial name
- NCT01931826
- Testing
- Endoscopic treatment, Total EGDS+ endoscopy
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade Estadual de Ciências da Saúde de Alagoas
Nasal Polyps
Mometasone Furoate Nasal Spray for Treatment of Nasal Polyposis After Surgery (Study P03218)
This study was conducted to evaluate the effectiveness of mometasone nasal spray in preventing polyp relapse/symptom worsening in patients after surgical treatment of nasal polyps.
- Trial name
- NCT00731185
- Testing
- Mometasone Furoate Nasal Spray
- Volunteers
- 162 people
- Sponsor
- Organon and Co
Peptic Ulcer
Study to Assess the Efficacy and Safety of Somatostatin in the Treatment of Acute Severe Upper Gastrointestinal Bleeding
To assess the efficacy and safety of the early administration of somatostatin in infusion during 72 hours plus 2 boluses, compared to placebo in the control of acute severe UGIB with suspicion of PUB.
- Trial name
- NCT00152399
- Testing
- Somatostatin UCB (drug)
- Where
- 22 sites in Belgium, France and 4 more
- Volunteers
- 370 people
- Sponsor
- UCB Pharma
Crohn Disease
Endoscopic Balloon Dilation vs Surgery to Treat Short Strictures in Fibrostenosing Crohns Disease: An RCT
There is currently no standard management to guide the clinicians in treating patients with fibrostenotic disease. European Crohns and Colitis Organization [ECCO] recently developed a topical review on prediction, diagnosis and…
- Trial name
- NCT03735355
- Testing
- Surgery, TTS balloon dilation
- Volunteers
- 40 people
- Sponsor
- McMaster University
Internal Hemorrhoid
Recurrence Rate of Minimally Invasive Endoscopic Treatment of Internal Hemorrhoids
2.1 Main objective: To observe the short-term and long-term recurrence rates of various endoscopic minimally invasive treatment methods for internal hemorrhoids and different time points of endoscopic minimally invasive treatment…
- Trial name
- NCT06250140
- Testing
- Tie up device
- Volunteers
- 900 people
- Sponsor
- Shenzhen Hospital of Southern Medical University
Acute Uncomplicated Appendicitis
Direct Visualization ERAT Versus Laparoscopic Appendectomy in Adults With Acute Uncomplicated Appendicitis
This study compares two ways of treating acute uncomplicated appendicitis, which is a mild form of appendicitis. In the Direct Visualization ERAT group, participants will receive Endoscopic Retrograde Appendicitis Therapy (ERAT).
- Trial name
- E-APPEND (NCT07230379)
- Testing
- Direct Visualization Endoscopic Retrograde Appendicitis Therapy, Laparoscopic appendectomy
- Where
- 14 sites in China
- Volunteers
- 376 people
- Sponsor
- Changhai Hospital
Cirrhosis, Variceal Bleeding
EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment
This study is performed to compare the efficacy and safety of EBL alone and EBL combined with propranolol in patients who were previously performed endoscopic variceal treatment.
- Trial name
- NCT00966082
- Testing
- endoscopic band ligation, endoscopic band ligation+Propranolol
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Korea University
Lumbar Disc Herniation
Full-Endoscopic vs Open Discectomy for the Treatment of Symptomatic Lumbar Herniated Disc
The purpose of this study is to compare the clinical and radiographic outcomes of full endoscopic lumbar discectomy versus open lumbar decompression for the treatment of lumbar herniated discs in which the patient's leg pain is…
- Trial name
- NCT02441959
- Testing
- Lumbar discectomy Open, Lumbar discectomy Endoscopic
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
GIT Bleeding
Impact of Diagnostic and Therapeutic Upper and Lower Gastrointestinal Endoscopic Management on Critically Ill Patients in Fayoum University Hospitals
Prospective study to evaluate the diagnostic and prognostic value of upper and lower gastrointestinal endoscopy in ICU
- Trial name
- NCT07829978
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University
Gastric Adenoma, Early Gastric Cancer
The Effect of Proton Pump Inhibitor and Polaprezinc Combination Therapy for Healing of Endoscopic Submucosal Dissection-induced Ulcer
Endoscopic submucosal dissection (ESD) is an advanced technique that enables en bloc resection of superficial tumors in the gastrointestinal tract.
- Trial name
- NCT02243618
- Testing
- Polaprezinc, Rebamipide
- Where
- South Korea
- Volunteers
- 153 people
- Sponsor
- Yonsei University
Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Clinical Study of Double-Endoscopic Combined With Minimally Invasive Treatment for Early Gastric Cancer at Clinical Stage T1b
For patients diagnosed with early gastric cancer involving submucosal invasion, super-ESD indications, or lymph node metastasis, a combination of preoperative endoscopic ultrasound and abdominal contrast-enhanced CT was utilized…
- Trial name
- NCT06934824
- Testing
- Sixty patients with early gastric cancer in stage T1bN0-1M0 were divided into Group A-N0 and Group B-N + according to the presence or absence of lymph node metastasis. When the enrolled patients und
- Volunteers
- 60 people
- Sponsor
- Hebei Medical University
Early Gastric Cancer, Endoscopic Submucosal Dissection
The Relationship Between Scar Formation and ESD Depth in Therapy for Gastric Carcinoma
This study is a single-center, prospective, group-controlled clinical trial, aiming to clarify the relationship between the depth of dissection and scar formation in the treatment of early gastric cancer by ESD, and to provide…
- Trial name
- NCT05323929
- Testing
- ESD
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Upper Gastrointestinal Bleeding
Hemostatic Powder Following Injection Therapy Versus Conventional Dual Therapy for Endoscopic Hemostasis for Non-variceal Upper Gastrointestinal Bleeding
Acute upper gastrointestinal hemorrhage (UGIH) is a common condition that leads to hospital admission, and has significant associated morbidity and mortality, especially in the elderly.
- Trial name
- NCT02717416
- Testing
- Endo-Clot, hemoclip or electrical coagulation
- Where
- South Korea
- Volunteers
- 226 people
- Sponsor
- Yonsei University
Benign Prostatic Hyperplasia (BPH)
French Aquablation Clinical Investigation Using Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue
Single arm, multi-center prospective clinical trial to determine the safety and effectiveness of the AQUABEAM System in the treatment of benign prostatic hyperplasia (BPH) in men 45 to 80 years of age.
- Trial name
- NCT03191734
- Testing
- AQUABEAM System
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- PROCEPT BioRobotics
Emphysema
Endoscopic Lung Volume Reduction Coil Treatment in Patients With Chronic Hypercapnic Respiratory Failure
Endoscopic lung volume reduction coil treatment is a treatment option for selected patients with severe emphysema. In the advanced stages, emphysema may lead to chronic hypercapnic respiratory failure.
- Trial name
- NCT02996149
- Testing
- Endoscopic lung volume reduction coil treatment
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Obesity
Bariatric Endoscopy for Treatment of Obesity
A single-center, randomized trial will be conducted in order to compare three Endoscopic Gastroplasty (EG) techniques in obese patients (BMI 30-44.99 kg/m2) at Gastroenterology and Gastrointestinal Endoscopy Unit, Mater Olbia…
- Trial name
- NCT04854317
- Testing
- Endoscopic gastroplasty
- Where
- Italy
- Volunteers
- 189 people
- Sponsor
- Mater Olbia Hospital
Clarify the Therapeutic Differences Between Robot Assisted Endoscopic Clearance and Traditional Puncture and External Drainag
Effect of Minimally Invasive Surgical Assisted by Robots on Intraventricular Hemorrhage
Clarify the therapeutic differences between robot assisted endoscopic clearance and traditional puncture and external drainage, and establish a new minimally invasive surgical diagnosis and treatment strategy for intraventricular…
- Trial name
- NCT06486480
- Testing
- Using robot assisted endoscopy to clear intraventricular hemorrhage
- Volunteers
- 143 people
- Sponsor
- Jin Hu