Clinical trials: Therapy Effect
Musculoskeletal Abnormalities, Obesity
GLP-1R Actions on Muscle and the Skeleton
The GRAMS study objectives are to assess the musculoskeletal changes that occur after weight loss using GLP-1 based therapy. A lifestyle intervention with diet and exercise is included to assess any mitigating effects are…
- Conditions
- Musculoskeletal Abnormalities, Obesity, Sarcopenic Obesity, Osteoporosis
- Trial name
- GRAMS (NCT07154719)
- Testing
- Tirzepatide, Lifestyle toolkit
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Pennington Biomedical Research Center
Breast Cancer Screening, Breast Cancer Awareness
Effect of a Health Belief Model Based Digital Nudge Intervention on Breast Cancer Screening
This study aims to evaluate the effect of a multi-component digital nudge intervention based on the Health Belief Model on breast cancer awareness, health beliefs, and screening behaviors among women aged 40-69.
- Conditions
- Breast Cancer Screening, Breast Cancer Awareness, Health Belief Model
- Trial name
- NCT07907419
- Testing
- Multicomponent Digital Nudging Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Balance Changes
Effect of the Suboccipital Inhibition Technique on Balance Changes
Postural balance is an essential capacity for functional autonomy and the performance of activities of daily living, relying on the continuous integration of visual, vestibular, and somatosensory information.
- Trial name
- NCT07670819
- Testing
- Intervention Technique
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
HIV, Inflammation
PET/CT Imaging Companion Study To ACTG A5314
HIV-infected individuals on antiretroviral therapy (ART) are at increased risk for cardiovascular disease (CVD), likely due to chronically increased inflammation.
- Conditions
- HIV, Inflammation, Atherosclerosis
- Trial name
- PET/CTMTX (NCT02312219)
- Testing
- Folic Acid, Low Dose Methotrexate
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Hepatocellular Carcinoma
PAtient-PHYsician Relationship Assessment
I) Introduction Patients with cancer face difficult choices that require balancing competing priorities such as survival, functional capacity and symptom relief.
- Trial name
- PAPHYRA (NCT05729230)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Erasme University Hospital
Multiple Sclerosis
Effect of Motor Entrainment to Auditory Cues and Music During Walking on Quality of Movement and Perceived Fatigue in Persons With Multiple Sclerosis (PwMS)
The study investigates the effect of different conditions of auditory cueing and music on walking quality and perceived fatigue in persons with multiple sclerosis compared to healthy controls.
- Trial name
- NCT03281330
- Testing
- auditory cues and music during walking
- Where
- 3 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Hasselt University
Pain, Fatigue
Integrative Medicine Consultation for Patients With Pain or Fatigue
Patients with a diagnosis of chronic fatigue or pain benefit minimally from a conventional medical evaluation yet consume a large amount of medical resources and time.
- Trial name
- NCT01058265
- Testing
- Integrative, Standard
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Mayo Clinic
Pain, Acute, Child Behavior
Investigation of the Effect of White Noise Listening on Pain and Comfort During Invasive Interventions in Newborns
Comfort, distress and the absence of pain can be described as free from anxiety, somewhat enjoyable and ease (peaceful) situation.
- Conditions
- Pain, Acute, Child Behavior, Newborn
- Trial name
- IEWNLPCDIIN (NCT05103800)
- Testing
- invasive interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Batman University
Lupus Erythematosus, Systemic
A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Systemic Lupus Erythematosus in adult patients with moderate to severe symptoms.
- Trial name
- OPUS-1 (NCT05648500)
- Testing
- Cenerimod
- Where
- 198 sites in United States, Argentina and 15 more
- Volunteers
- 470 people
- Sponsor
- Viatris Innovation GmbH
Cirrhosis, Portal Hypertension
A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis
Endothelin is a human hormone which has been associated with increased portal pressure in patients with liver cirrhosis (also called portal hypertension). Ambrisentan blocks the effects of endothelin.
- Conditions
- Cirrhosis, Portal Hypertension, Ascites
- Trial name
- NCT03827200
- Testing
- Ambrisentan
- Where
- 6 sites in Spain
- Volunteers
- 19 people
- Sponsor
- Noorik Biopharmaceuticals AG
Microbial Colonization
Vaginal Microbiota, and STI/HIV Risk Among Adolescent Girls and Young Women
The investigators are doing a study on the bacteria that normally live in the vagina and what effect, if any, Depo-Provera has on the bacteria.
- Trial name
- AIMS (NCT03196492)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hyperlipoproteinemia, Metabolic Syndrome
Effect of Niacin/Laropiprant on Postprandial Lipoprotein Metabolism in Patients With Dyslipoproteinemia
The study is designed to evaluate the effect of Niacin/Laropiprant on postprandial lipoprotein metabolism, postprandial glucose metabolism, postprandial monocyte function, and postprandial biomarkers of endothelial dysfunction…
- Trial name
- NCT01239992
- Testing
- Niacin/ Laropiprant
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Face
Effects of Hard Gum Chewing on Facial Soft Tissue Morphology
This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults.
- Trial name
- GUM-3D (NCT07726511)
- Testing
- Hard Gum Chewing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- UConn Health
Opioid Use, Exercise
Effect of Increased Pain Tolerance on Exercise Performance
Clinical prescription and use of opioids is a clear problem in large parts of the world and has the recent years received an increasing publicity in sports.
- Trial name
- NCT03934411
- Testing
- Tramadol
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Vaginal Birth After Cesarean
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Trial name
- NCT00294411
- Testing
- elective cesarean section
- Sponsor
- Chinese University of Hong Kong
Healthy
Effect of Essential Oils in Aromatherapy on Emotional Relaxation
The purpose of this study is to examine and compare electroencephalography (EEG) changes in human subjects directly after inhalation of essential oils from five Thai aromatherapies.
- Trial name
- NCT01443871
- Testing
- Aromatherapy, Pure water
- Where
- 2 sites in Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Phayao
Type 1 Diabetes
Monocyte Function and Inflammation in Type 1 Diabetes and Its Modulation
Type I diabetes (T1DM) is associated with an increased risk of vascular complications. While the precise mechanism(s) by which diabetes accelerates atherosclerosis has not been elucidated, several lines of evidence point to the…
- Trial name
- NCT00441844
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Diarrhea, Helminthiasis
The Effect of an Urban Sanitation Intervention on Child Health
The purpose of this study is to determine the health impact of a basic sanitation intervention in Maputo, Mozambique.
- Trial name
- MapSan (NCT02362932)
- Testing
- Sanitation
- Where
- Mozambique
- Volunteers
- 1,866 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Rotator Cuff Tear Arthropathy
the Effect of Core Stability on Hand Functions
Determining the factors affecting hand function after upper limb injuries is very important for maintaining independence in daily living activities.
- Trial name
- NCT06105398
- Testing
- clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Gülçe İrem Yalçınkaya
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.