Clinical trials: Therapy Effect
Obesity
Effect of Diltiazem Administration on CP-945,598 Pharmacokinetics
A recently completed clinical drug interaction study of CP-945,598 with ketoconazole, a potent CYP3A inhibitor, showed that coadministration of CP-945,598 with ketoconazole results in an approximately 5-fold increase in…
- Trial name
- NCT00645463
- Testing
- CP-945,598
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Clinical Reasoning, Orotracheal Suctioning
Animation-Based Orotracheal Suction Training for Expert Nurses
This randomized controlled trial aimed to evaluate the effect of animation-based orotracheal suction training on the clinical reasoning competency and knowledge levels of expert pediatric nurses.
- Conditions
- Clinical Reasoning, Orotracheal Suctioning, Nursing Education
- Trial name
- ABOST-EN (NCT07688993)
- Testing
- Animation-Based Orotracheal Suction Training, PowerPoint-Supported Traditional Training
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Nasopharyngeal Carcinoma
Effect of Nurse-Led Individualized Follow-Up Intervention on Patients With Nasopharyngeal Carcinoma
The incidence of nasopharyngeal carcinomas (NPCs) is highly unbalanced around the globe, primarily concentrated in East and Southeast Asia.There is no well-conducted, larger randomized controlled trials (RCT) outlining a gold…
- Trial name
- NCT06572293
- Testing
- Nurse-led intervention
- Volunteers
- 250 people
- Sponsor
- Fujian Cancer Hospital
Malignancy
Does Transcranial Magnetic Stimulation of the Cingulate Cortex Modulate the Perception of Dyspnoea?
The treatment we are studying is Transcranial Magnetic Stimulation (TMS). In TMS, an electromagnetic pulse is passed into the brain through a coil placed on the head.
- Trial name
- TMS (NCT00830921)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Pulp Exposure, Dental, Pulp Disease, Dental
The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy
This study employs saliva-based DNA analysis to investigate the effect of genetic polymorphisms, particularly SNPs in MMP, TIMP, TNF-α, and BMP genes, on the success of vital pulp therapy in permanent teeth with pulpitis…
- Conditions
- Pulp Exposure, Dental, Pulp Disease, Dental, Pulp Caping, Pulpitis
- Trial name
- NCT07130214
- Testing
- Biodentine
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ataturk University
Labor Analgesia, Labor Pain
Effect of Dural Puncture Epidural Analgesia on Oxytocin in Early vs Late Labor
Oxytocin is a key hormone that regulates uterine contractions during labor. Dural Puncture Epidural Analgesia (DPEA) is a modern technique for labor pain relief that provides faster onset and more reliable analgesia than standard…
- Conditions
- Labor Analgesia, Labor Pain, Oxytocin
- Trial name
- DPEA-OXY (NCT07873814)
- Testing
- Dural Puncture Epidural Analgesia (DPEA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Atrial Fibrillation
Pacemaker Holter Assessment of the Effect of BMS-914392 on Atrial Fibrillation Burden
The purpose of the study is to determine whether treatment with BMS-914392 is safe, well tolerated and associated with a reduction of atrial fibrillation burden in patients with paroxysmal atrial fibrillation and permanent…
- Trial name
- NCT01356914
- Testing
- BMS-914392
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Bristol-Myers Squibb
Depressive Symptoms, Fatigue
Programs to Support You During Chemotherapy (Pro-You)
This randomized pilot clinical trial studies Yoga Skills Training or attention control in reducing fatigue and depressive symptoms during chemotherapy in patients with stage II-IV colorectal cancer.
- Conditions
- Depressive Symptoms, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Stage IIA Colon Cancer
- Trial name
- Pro-You (NCT02148406)
- Testing
- Yoga Skills Training (YST), questionnaire administration, fatigue and depressive symptom assessment and management
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Radiography, Dentistry
Can a Digital Education Program in Radiographic Imaging Technique for Dental Professionals Improve Image Quality?
The goal of this clinical trial is to learn if a digital education program designed for dental professionals can lead to radiographic examinations of better quality.
- Trial name
- NCT06442904
- Testing
- Digital education program
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Umeå University
Metabolic Syndrome (MetS)
Preliminary Effect of a Health Information Literacy Enhancement Program for Individuals With Metabolic Syndrome
The purpose of this study is to evaluate the preliminary effect of a health-information literacy promotion program for individuals with Metabolic Syndrome (including its subtypes) based on the Health Empowerment Theory.
- Trial name
- NCT07051733
- Testing
- Health Information Literacy Enhancement
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meihua Ji
Hepatitis C Virus Infection, Response to Therapy of
Effects of Activity and Education Program on Patients With Chronic Hepatitis C Infection
This 4-year project will be guided by a biobehavioral model for the study of exercise interventions in two phases with the purposes to : 1.
- Trial name
- NCT01572233
- Testing
- Personalized Physical Activity and Psycho-Education (PPAPE) Program
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Pulmonary Hypertension, Nursing Care
Dynamic Mixed Learning Module in Pulmonary Hypertension Patients
This study was conducted to evaluate the effect of the Dynamic Blended Learning Module developed for patients diagnosed with pulmonary hypertension (PH) on symptom management.
- Conditions
- Pulmonary Hypertension, Nursing Care, Learning
- Trial name
- Learning (NCT07429552)
- Testing
- Symptom Management
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Antimullerian Hormone, Ovarian Cysts
The Effect of Surgery for Non Endometriosic Ovarian Cysts on Ovarian Reserve
The main objective is to evaluate the ovarian reserve after laparoscopic cystectomy. The secondary objective is the analysis of predictors of change in the ovarian reserve after surgery
- Conditions
- Antimullerian Hormone, Ovarian Cysts, Antral Follicle Count
- Trial name
- NCT02852447
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Corporacion Parc Tauli
Proprioceptive Disorders
The Acute Effect of Foam Rolling on Elbow Joint Sensorimotor Function
The purpose of this study is to investigate the acute effects of foam rolling on elbow joint sensorimotor function with healthy participants . Study group will receive foam rolling exercise.
- Trial name
- NCT03516149
- Testing
- Foam Rolling Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Quality of Life
Effect of Colon Delivered Vitamin C on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults
Recent studies have shown that many vitamins, if consumed in high daily dosages or delivered to the colon, can modulate the gut microbiota and their metabolites.
- Trial name
- NCT05598619
- Testing
- Vitamin C
- Where
- Ireland
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Menopause
Hot Flash and Night Sweat Virtual Study
The purpose of this research study is to evaluate the effectiveness of the study product on vasomotor symptoms (VMS) and overall menopause symptoms in healthy women, who are perimenopausal or postmenopausal, and aged 40 - 65.
- Trial name
- NCT06289907
- Testing
- Bonafide-HF3.0
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Bonafide Health
Healthy
A Study to Evaluate the Drug-Drug Interaction Between Enlicitide Decanoate (MK-0616) and Alendronate in Healthy Adult Participants (MK-0616-027)
The goal of this study is to learn what happens to a single dose of alendronate over time in a healthy participant's body when the participant is given a single dose of enlicitide decanoate.
- Trial name
- NCT06772792
- Testing
- Alendronate, Enlicitide Decanoate
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV Infections, Hepatitis C
Effects of HIV and Hepatitis C Virus on the Brain
This study will determine the effects that HIV and hepatitis C virus have on thinking abilities and whether the viruses affect brain chemistry.
- Trial name
- NCT00494936
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ototoxicity
Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment
The purpose of this study is to evaluate whether DB-020 administered via an injection in the middle ear prevents hearing loss in participants who will receive high doses of cisplatin as part of their treatment for cancer.
- Trial name
- NCT04262336
- Testing
- DB-020
- Where
- 8 sites in United States, Australia
- Volunteers
- 22 people
- Sponsor
- Decibel Therapeutics
Quality of Life, Exercise
The Effect of N-Acetylcystein on Quality of Life and Air Trapping During Rest and After Exercise
Treatment of COPD patients depends on the stage of the disease. First of all it is strongly recommended quit smoking, then bronchodilators drugs are added.
- Trial name
- NAC (NCT00476736)
- Testing
- Effect on small airways (N-Acetylcystein)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
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