Clinical trials: Therapy Effect
Migraine Disorders
tDCS for the Treatment of Migraine
The aim of this study is to evaluate an optimized protocol of tDCS that normalize the lack of habituation and efficiency of inhibitory cortical circuits in migraine patients.
- Trial name
- NCT02562196
- Testing
- tdcs
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco
Stroke, Sabacute Stroke
Bilateral Robot-assisted Upper Extremity Rehabilitation on Motor Recovery in People With Subacute Stroke
The goal of this clinical trial is to study the clinical effects of a robotic rehabilitation treatment through a bilateral exoskeleton (Bilateral Robot-Assisted Therapy-BRAT) during standard rehabilitation, on motor recovery…
- Trial name
- BILAX (NCT06906588)
- Testing
- Experimental, Control
- Where
- 3 sites in Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS San Raffaele Roma
Drug-Induced Liver Injury
Immune Responses in Hepatocellular Carcinoma Patients After Treatment With Direct Acting Antiviral Drugs
Case control Study to assess the difference of immune cell responses between patients with chronic HCV- related liver cirrhosis who develop HCC after treatment with DAAs and those who do not develop HCC
- Trial name
- NCT03602703
- Testing
- Flow cytometry and Western Blot analysis
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Elderly People, Depressive Symptoms
Bibliotherapy-based Psychoeducation Program the Effect of Elderly Individuals on Depression and Hopelessness Levels
Bibliotherapy has been mainly focused on the social and emotional problems of children and young people, and studies with the elderly are very few.
- Conditions
- Elderly People, Depressive Symptoms, Despondency
- Trial name
- NCT05652803
- Testing
- bibliotherapy-based psychoeducation program, psychoeducation program
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
COPD, Anxiety
Effect of Therapeutic Touch on Sleep Quality and Anxiety in Individuals With Chronic Obstructive Pulmonary Disease
Purpose: The purpose is to determine the effect of therapeutic touch on the sleep quality and anxiety of individuals with chronic obstructive pulmonary disease.
- Conditions
- COPD, Anxiety, Sleep
- Trial name
- NCT04842903
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Abant Izzet Baysal University
Obesity & Overweight, Type 2 Diabetes
Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy
This is a 17 - week study consisting of a one - week run - in period and a 16 - week intervention. The 16 - week pilot interventions aims to increase hydration in those beginning GLP - 1 RA therapy.
- Conditions
- Obesity & Overweight, Type 2 Diabetes, Type 2 Diabetes (Adult Onset), Obesity Type 2 Diabetes Mellitus
- Trial name
- NCT07641361
- Testing
- Hydration Plus, Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York at Buffalo
Metastatic Colorectal Cancer
A Real-World Study to Learn More About the Order of Different Treatments and Their Effects in People With Metastatic Colorectal Cancer Receiving Their Third and Fourth Line of Treatment
This is an observational study in which data already collected from people with metastatic colorectal cancer will be studied. Metastatic colorectal cancer (mCRC) is a cancer of the colon (large bowel) or the rectum (lowest part…
- Trial name
- RegoSeq (NCT06137170)
- Testing
- Regorafenib (Stivarga, BAY73-4506)
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 121 people
- Sponsor
- Bayer
Polycythemia
Effect of Phlebotomy on Heartrate in Polycythemia Patients
Single-centre, observational within-subject design: patients that undergo phlebotomies regularly for polycythemia will be measured continuously by wearables one week before until one week after a phlebotomy, for three…
- Trial name
- NOSFERATU (NCT05396170)
- Testing
- phlebotomy
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Leiden University Medical Center
Mild Cognitive Impairment (MCI)
Effect of Inspiratory Muscle Training in Cognition
The goal of this clinical trial is to examine the effect of a respiratory muscle strengthening program on the cognitive and physical functioning of patients with neurocognitive disorders (Mild Cognitive Impairment) or those…
- Trial name
- NCT07146373
- Testing
- Inspiratoty Muscle training, Usual Care
- Where
- Greece
- Volunteers
- 76 people
- Sponsor
- University of West Attica
Gender Dysphoria
Effect of Nitropaste in Chest Masculinizing Surgery
Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature.
- Trial name
- NCT06428669
- Testing
- Nitro-Bid 2 % Topical Ointment
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Virginia
Uterus Involution, Early Postpartum Hemorrhage
Date Consumption and Uterine Involution
There are many studies in the literature examining the effects of dates on pregnancy, birth and postpartum processes. However, no study has been found that examines the effect of women on the involution process in the early…
- Trial name
- NCT05072769
- Testing
- Date Fruit
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Colorectal Cancer
Effect of Preoperative ERAS Education on Recovery After Colorectal Surgery
This randomized controlled trial describes the design and conduct of ERAS-based preoperative education in patients with colorectal cancer undergoing colorectal surgery.
- Trial name
- NCT07324369
- Testing
- ERAS-Based Preoperative Education, Standard Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Izmir Katip Celebi University
Chemotherapy-induced Anemia
Biosimilar Retacrit® in the Treatment of Chemotherapy-induced Anaemia in Oncology and Haematology
The aim of this study is to describe, in a real-life context, the impact of an epoetin alpha biosimilar, Retacrit®, on anaemia in patients receiving chemotherapy, according to concomitant iron supplementation.
- Trial name
- SYNERGY (NCT02158169)
- Where
- 69 sites in France
- Volunteers
- 2,167 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Peripheral Lung Tumor
Padeliporfin VTP Using Robotic Assisted Bronchoscopy in Peripheral Lung Cancer
Phase 1/1b, safety, feasibility, and light dose titration study followed by further study of therapeutic ablation effects. Patients with high risk of peripheral primary lung cancer, stage 1A1/1A2, for whom surgical treatment is…
- Trial name
- NCT05918783
- Testing
- Padeliporfin Vascular Targeted Photodynamic (VTP) therapy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Impact Biotech Ltd
Healthy Participants
A Study to Investigate the Pharmacokinetics of Ethinyl Estradiol and Levonorgestrel When Given Alone and in Combination With Baxdrostat in Healthy Females of Non-childbearing Potential
The main purpose of the study is to assess the effect of multiple doses of baxdrostat on the pharmacokinetics (PK) of a single dose of combined oral ethinyl estradiol (EE) and levonorgestrel (LNG).
- Trial name
- NCT06657105
- Testing
- EE/LNG, Baxdrostat
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Injection Pain Prevention, Injection Pain
The Effect of Simultaneous Versus Sequential Intramuscular Vaccine Injections on Pain Levels in Infants
This study was designed as a randomized controlled trial comparing simultaneous and sequential administration of intramuscular vaccines in infants.
- Trial name
- NCT07455305
- Testing
- Simultaneous injection, Sequential injection
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Spasticity, Muscle, Cerebral Palsy
Effect of Session Frequency of rESWT on Gastrocnemius Muscle Spasticity in Children With Spastic Type Cerebral Palsy
Spasticity, defined as a velocity dependent increase in tonic stretch reflexes, is one of the most prominent motor problems that occur in patients with cerebral palsy (CP).
- Conditions
- Spasticity, Muscle, Cerebral Palsy, Child; Spastic
- Trial name
- NCT04574622
- Testing
- radial Extracorporeal Shockwave Therapy
- Where
- Indonesia
- Volunteers
- 14 people
- Sponsor
- Rizky Kusuma Wardhani
Vitamin D Deficiency
The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile
Participants in this study will be randomized to receive either oral vitamin D pills OR ultraviolet light treatment. The investigators will compare how these two methods of raising vitamin D levels will affect cholesterol levels.
- Trial name
- NCT01688102
- Testing
- Oral Vitamin D3, Ultraviolet Light
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Digestive Health, Quality of Life
Protein-Prebiotic Wellbeing Study
Healthy participants with self-reported GI complaints will consume the protein supplement that they normally use for recovery purposes after exercise during a 3-week baseline period, followed by a 3-week intervention period in…
- Trial name
- NCT05303753
- Testing
- fermented dairy protein with prebiotic fiber
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Coronary Artery Disease (CAD), Cardiac Rehab
The Effect of Cardiac Rehabilitation on Ferroptosis in Patients With Coronary Artery Disease
Coronary artery disease (CAD) remains a major global health concern and is the leading cause of cardiovascular mortality worldwide.
- Conditions
- Coronary Artery Disease (CAD), Cardiac Rehab, Ferroptosis
- Trial name
- NCT07722637
- Testing
- Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
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